Primaquine use while Breastfeeding

Primaquine Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the use of primaquine during breastfeeding. If it is required, the mother and infant should be tested for G6PD deficiency before primaquine is given to a woman who is breastfeeding. It may be used in breastfeeding mothers and infants with normal G6PD levels.[1]

In general, very small amounts of antimalarial drugs are excreted in the breast milk of lactating women. Because the quantity of antimalarial drugs transferred in breast milk is insufficient to provide adequate protection against malaria, infants who require chemoprophylaxis must receive the recommended dosages of antimalarial drugs.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Chloroquine, Mefloquine

References

1. Arguin PM, Tan KR. Chapter 3. Infections diseases related to travel. Malaria. In, Centers for Disease Control and Prevention. CDC Health Information for International Travel 2014. New York: Oxford University Press. 2014. http://wwwnc.cdc.gov/travel/yellowbook/2014/chapter-3-infectious-diseases-related-to-travel/malaria

Primaquine Identification

Substance Name

Primaquine

CAS Registry Number

90-34-6

Drug Class

  • Anti-Infective Agents
  • Antimalarials

Administrative Information

LactMed Record Number

801

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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