Primaquine use while Breastfeeding
Primaquine Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the use of primaquine during breastfeeding. If it is required, the mother and infant should be tested for G6PD deficiency before primaquine is given to a woman who is breastfeeding. It may be used in breastfeeding mothers and infants with normal G6PD levels.[1]
In general, very small amounts of antimalarial drugs are excreted in the breast milk of lactating women. Because the quantity of antimalarial drugs transferred in breast milk is insufficient to provide adequate protection against malaria, infants who require chemoprophylaxis must receive the recommended dosages of antimalarial drugs.[2]
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
References
1. Shealy K. Chapter 7. International travel with infants and young children. In. Centers for Disease Control and Prevention. CDC Health Information for International Travel 2010. Atlanta: U.S. Department of Health and Human Services, Public Health Service. 2009. http://wwwnc.cdc.gov/travel/yellowbook/2010/chapter-7/travel-and-breastfeeding.aspx#1889
2. Arguin PM, Steele SF. Chapter 2. The pre-travel consultation. Malaria. In. Centers for Disease Control and Prevention. CDC Health Information for International Travel 2010. Atlanta: U.S. Department of Health and Human Services, Public Health Service. 2009. http://wwwnc.cdc.gov/travel/yellowbook/2010/chapter-2/malaria.aspx
Primaquine Identification
Substance Name
CAS Registry Number
90-34-6
Drug Class
- Anti-Infective Agents
- Antimalarials
Administrative Information
LactMed Record Number
801
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2010-03-23
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Primaquine use during Pregnancy
- Primaquine Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.


