Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Neosporin, Cortisporin Otic, Maxitrol, Polytrim, Triple Antibiotic, Polysporin, Neo-Poly-Dex, Neosporin Ophthalmic, Cortisporin Ophthalmic Suspension, Septa, Show all 82 »Antibiotic Ear, Neosporin Ophthalmic Ointment, Antibiotic Plus Pain Relief, Triple Antibiotic Ophthalmic Ointment, Cortisporin Ointment, Terramycin with Polymyxin B Sulfate, Betadine Antibiotic, Polysporin Ointment, Neosporin G U Irrigant, AK-Poly-Bac, Polysporin Ophthalmic, Triple Antibiotic Plus, Otocort Sterile Solution, Methadex, Polytracin Ophthalmic, Mycitracin Triple Antibiotic, Cortisporin Ophthalmic Ointment, Cortomycin, Otocort Sterile Suspension, Neo/PolyB/HC, Terak, Antibiotic with Pramoxine, Cortisporin Cream, Neoptic, AK-Trol, Dexacidin, Neocin, Neosporin + Pain Relief Neo to Go!, Neosporin Plus Maximum Strength Ointment, Masporin Otic, Cort-Biotic, Oti-Sone, Cortatrigen, Cortatrigen Modified, Pediotic, AK-Spore HC Otic Suspension, UAD Otic, Otimar, Otobiotic, Poly Pred, Cortomycin Eye Ointment, Neotricin HC, Ocu-Cort, Neosporin Plus, Neosporin Plus Maximum Strength, Drotic, Statrol, Triple Antibiotic HC Ophthalmic Ointment, Neo-Poly-Bac, Neocidin, Ocu-Spore-B, Poly-Dex, Dexasporin, Dexacine, Ocu-Trol, Polycin-B, Campho-Phenique Maximum Strength, Betadine Plus Antibiotic and Pain Reliever, Duospore, Polytracin, NPD Ophthalmic Ointment, Spectrocin Plus, Cortomycin Suspension, Tribiotic Plus, Medi-Quik, Ophthocort, Mycitracin Plus Pain Reliever, Neocidin Ophthalmic Solution, Lanabiotic, Ocu-Spore-G, Neocin-PG, Ocutricin

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

• Antiinfective Agents, Local
• Antibacterial Agents

Administrative Information

LactMed Record Number

550

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2011-01-31

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

• Polymyxin B ophthalmic Consumer Information
• Polymyxin b sulfate Consumer Information
• Breastfeeding Support Group
• Safe Medications during Breastfeeding
• Medicine use while Breastfeeding
• Medicine use during Pregnancy

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.