Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Cortisporin Otic, Neosporin, Maxitrol, Polytrim, Triple Antibiotic, Polysporin, Cortisporin Ophthalmic Suspension, Polysporin Ointment, Polysporin Ophthalmic, Neo-Poly-Dex, Show all 84 »Neosporin Ophthalmic Ointment, Antibiotic Plus Pain Relief, Neosporin Ophthalmic, Septa, Cortisporin Ointment, Cortisporin Cream, Triple Antibiotic Ophthalmic Ointment, Dexasporin, Polytracin Ophthalmic, Triple Antibiotic HC Ophthalmic Ointment, Neosporin Plus Maximum Strength Ointment, Mycitracin Triple Antibiotic, Antibiotic Ear, Statrol, Terak, Antibiotic with Pramoxine, Pediotic, Terramycin with Polymyxin B Sulfate, AK-Spore HC Otic Suspension, Poly Pred, Dexacine, Cortomycin, Methadex, Cortisporin Ophthalmic Ointment, Polycin-B, Ocu-Cort, Otimar, Otocort Sterile Suspension, UAD Otic, Cortatrigen, Cortatrigen Modified, Masporin Otic, Ocu-Spore-B, Neocin, Drotic, Cort-Biotic, Otocort Sterile Solution, Otobiotic, Neosporin Plus, Neosporin Plus Maximum Strength, Neo-Poly-Bac, Cortomycin Eye Ointment, Neotricin HC, Neocidin, Ocutricin, Medi-Quik, AK-Spore Ointment, Neosporin G U Irrigant, Oti-Sone, Tribiotic Plus, Triple Antibiotic Plus, Campho-Phenique Maximum Strength, NPD Ophthalmic Ointment, Dexacidin, AK-Trol, Neosporin + Pain Relief Neo to Go!, AK-Poly-Bac, Polytracin, Betadine Antibiotic, Betadine Plus Antibiotic and Pain Reliever, Ophthocort, Ocu-Trol, Poly-Dex, Lanabiotic, Cortomycin Suspension, Neo/PolyB/HC, Mycitracin Plus Pain Reliever, AK-Spore, Neocidin Ophthalmic Solution, Spectrocin Plus, Neocin-PG, Neoptic, Ocu-Spore-G, Duospore

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

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