Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Cortisporin Otic, Neosporin, Polytrim, Maxitrol, Polysporin, Cortisporin Ophthalmic Suspension, Triple Antibiotic, Terramycin with Polymyxin B Sulfate, Neosporin Ophthalmic, Neosporin Ophthalmic Ointment, Show all 84 »Cortisporin Ointment, Antibiotic Plus Pain Relief, Polysporin Ophthalmic, Neo-Poly-Dex, Polysporin Ointment, Polytracin Ophthalmic, Neoptic, Cortisporin Cream, AK-Spore HC Otic Suspension, Dexacidin, Betadine Antibiotic, Dexasporin, Septa, Triple Antibiotic HC Ophthalmic Ointment, Methadex, Antibiotic with Pramoxine, Statrol, Poly-Dex, Pediotic, Oti-Sone, Polycin-B, Neocin, Poly Pred, Neosporin + Pain Relief Neo to Go!, Otimar, Neo-Poly-Bac, Cortatrigen Modified, Otocort Sterile Suspension, Drotic, Cortomycin Eye Ointment, Cortomycin, Masporin Otic, Otocort Sterile Solution, Cort-Biotic, Neosporin Plus Maximum Strength, Neotricin HC, Neosporin Plus, Ocu-Cort, Terak, Neosporin G U Irrigant, Otobiotic, Cortatrigen, Antibiotic Ear, Neo/PolyB/HC, Cortisporin Ophthalmic Ointment, UAD Otic, Neocidin Ophthalmic Solution, Polytracin, Medi-Quik, Duospore, Betadine Plus Antibiotic and Pain Reliever, Ophthocort, Mycitracin Triple Antibiotic, AK-Poly-Bac, Spectrocin Plus, Lanabiotic, Triple Antibiotic Plus, Neosporin Plus Maximum Strength Ointment, Tribiotic Plus, AK-Spore Ointment, Triple Antibiotic Ophthalmic Ointment, Ocu-Spore-G, Neocidin, Neocin-PG, Mycitracin Plus Pain Reliever, AK-Spore, Ocutricin, NPD Ophthalmic Ointment, Campho-Phenique Maximum Strength, Ocu-Spore-B, AK-Trol, Dexacine, Ocu-Trol, Cortomycin Suspension

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

  • Antiinfective Agents, Local
  • Antibacterial Agents

Administrative Information

LactMed Record Number

550

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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