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Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Neosporin, Cortisporin Otic, Polytrim, Maxitrol, Triple Antibiotic, Polysporin, Antibiotic Plus Pain Relief, Antibiotic Ear, Neo-Poly-Dex, Cortisporin Ophthalmic Suspension, Show all 90 »Triple Antibiotic Ophthalmic Ointment, Polysporin Ophthalmic, Terramycin with Polymyxin B Sulfate, Polytracin Ophthalmic, Neosporin + Pain Relief Neo to Go!, Septa, AK-Poly-Bac, Neosporin Ophthalmic, Polysporin Ointment, Otimar, Pediotic, Neosporin Ophthalmic Ointment, Cortisporin Ointment, Betadine Antibiotic, Antibiotic with Pramoxine, Ophthocort, Terak, Polycin, Triple Antibiotic HC Ophthalmic Ointment, Otocort Sterile Suspension, Lanabiotic, Neosporin Plus Maximum Strength, Cortomycin Suspension, Cortisporin Ophthalmic Ointment, Neo/PolyB/HC, Neosporin Plus Maximum Strength Ointment, AK-Spore, Neocidin Ophthalmic Solution, Cortomycin, Ocu-Spore-G, Cortatrigen Modified, Otobiotic, Cortisporin Cream, Statrol, Neosporin G U Irrigant, Poly Pred, Neosporin Plus, Oti-Sone, Cort-Biotic, Masporin Otic, Drotic, Otocort Sterile Solution, Neoptic, Cortatrigen, UAD Otic, AK-Spore HC Otic Suspension, NPD Ophthalmic Ointment, Ocu-Spore-B, Neocin, Ocutricin, Neo-Polycin HC, Medi-Quik, Tribiotic Plus, Mycitracin Triple Antibiotic, AK-Spore Ointment, Neocidin, Ocu-Cort, Neo-Poly-Bac, Neotricin HC, ProCoMycin, Neo-Polycin, First Aid Triple Antibiotic with Pain Reliever, NEO TO GO!, Mycitracin Plus Pain Reliever, Methadex, Dexasporin, Dexacidin, AK-Trol, Dexacine, Poly-Dex, Ocu-Trol, Cortomycin Eye Ointment, Campho-Phenique Maximum Strength, Triple Antibiotic Plus, Spectrocin Plus, Polycin-B, Duospore, Betadine Plus Antibiotic and Pain Reliever, Polytracin, Neocin-PG

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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