Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Neosporin, Maxitrol, Cortisporin Otic, Polytrim, Triple Antibiotic, Polysporin, Polysporin Ointment, Cortisporin Ophthalmic Suspension, Polysporin Ophthalmic, Neo-Poly-Dex, Show all 84 »Terramycin with Polymyxin B Sulfate, Antibiotic Plus Pain Relief, Cortisporin Ointment, Neosporin Ophthalmic, Polytracin Ophthalmic, Antibiotic Ear, Septa, Otocort Sterile Solution, Neosporin Ophthalmic Ointment, AK-Poly-Bac, Ocu-Spore-G, Dexacidin, Ocu-Trol, Lanabiotic, Cortomycin Eye Ointment, Mycitracin Plus Pain Reliever, Otobiotic, Statrol, Ophthocort, AK-Trol, Poly-Dex, Pediotic, Cortisporin Ophthalmic Ointment, Neosporin + Pain Relief Neo to Go!, Ocu-Spore-B, Cortisporin Cream, Triple Antibiotic HC Ophthalmic Ointment, Neosporin Plus Maximum Strength Ointment, Poly Pred, Mycitracin Triple Antibiotic, Antibiotic with Pramoxine, Neosporin Plus, AK-Spore HC Otic Suspension, Masporin Otic, Drotic, Cortomycin, Neo-Poly-Bac, Cortatrigen Modified, Terak, UAD Otic, Neosporin Plus Maximum Strength, Oti-Sone, Ocu-Cort, Cort-Biotic, Cortatrigen, Otocort Sterile Suspension, Neosporin G U Irrigant, Otimar, AK-Spore, Betadine Antibiotic, Polytracin, Betadine Plus Antibiotic and Pain Reliever, Neocin, Ocutricin, Duospore, Medi-Quik, Spectrocin Plus, Triple Antibiotic Plus, Tribiotic Plus, Polycin-B, AK-Spore Ointment, Campho-Phenique Maximum Strength, Neoptic, Neocin-PG, Neocidin Ophthalmic Solution, Cortomycin Suspension, Neo/PolyB/HC, Neocidin, Triple Antibiotic Ophthalmic Ointment, NPD Ophthalmic Ointment, Dexasporin, Methadex, Dexacine, Neotricin HC

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

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