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Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Neosporin, Cortisporin Otic, Polytrim, Maxitrol, Polysporin, Triple Antibiotic, Cortisporin Ophthalmic Suspension, Antibiotic Plus Pain Relief, Polysporin Ointment, Neosporin Ophthalmic Ointment, Show all 87 »Antibiotic Ear, Terramycin with Polymyxin B Sulfate, Polysporin Ophthalmic, Neo-Poly-Dex, Cortatrigen, Dexacidin, Cortisporin Ointment, Triple Antibiotic HC Ophthalmic Ointment, Cortisporin Cream, Cortisporin Ophthalmic Ointment, Dexacine, Neosporin Ophthalmic, Neo-Poly-Bac, Betadine Antibiotic, Triple Antibiotic Ophthalmic Ointment, Otobiotic, Mycitracin Triple Antibiotic, Drotic, AK-Spore, Dexasporin, AK-Poly-Bac, Ophthocort, Neosporin + Pain Relief Neo to Go!, Triple Antibiotic Plus, Mycitracin Plus Pain Reliever, Neosporin Plus Maximum Strength Ointment, Lanabiotic, Otocort Sterile Solution, Antibiotic with Pramoxine, Cortatrigen Modified, Otimar, Masporin Otic, AK-Spore HC Otic Suspension, Ocu-Cort, Cortomycin Eye Ointment, Neocin, Cortomycin, Pediotic, Otocort Sterile Suspension, Statrol, Neotricin HC, Neosporin G U Irrigant, Terak, Ocutricin, Neosporin Plus Maximum Strength, UAD Otic, Cort-Biotic, Poly Pred, Oti-Sone, Neosporin Plus, Neoptic, Betadine Plus Antibiotic and Pain Reliever, Polytracin, First Aid Triple Antibiotic with Pain Reliever, ProCoMycin, Campho-Phenique Maximum Strength, Duospore, Neocidin, Spectrocin Plus, NEO TO GO!, AK-Spore Ointment, Polytracin Ophthalmic, Polycin-B, Medi-Quik, NPD Ophthalmic Ointment, Ocu-Spore-G, Tribiotic Plus, Neocidin Ophthalmic Solution, Septa, Cortomycin Suspension, Neocin-PG, Ocu-Spore-B, Methadex, AK-Trol, Ocu-Trol, Poly-Dex, Neo/PolyB/HC

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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