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Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Neosporin, Maxitrol, Cortisporin Otic, Polytrim, Triple Antibiotic, Polysporin, Polysporin Ophthalmic, Cortisporin Ophthalmic Suspension, Antibiotic Ear, Antibiotic Plus Pain Relief, Show all 85 »Septa, Neosporin Ophthalmic, Neo-Poly-Dex, Polysporin Ointment, Terramycin with Polymyxin B Sulfate, Cortisporin Ointment, Polytracin Ophthalmic, Cortisporin Ophthalmic Ointment, Cortatrigen, Neosporin Ophthalmic Ointment, AK-Poly-Bac, Poly Pred, Dexacine, Otocort Sterile Solution, Cortisporin Cream, Betadine Antibiotic, Poly-Dex, Triple Antibiotic Ophthalmic Ointment, Mycitracin Triple Antibiotic, Neocin, Triple Antibiotic HC Ophthalmic Ointment, Ophthocort, Dexacidin, Tribiotic Plus, Otobiotic, Ocu-Spore-B, Mycitracin Plus Pain Reliever, UAD Otic, Neosporin Plus Maximum Strength Ointment, Pediotic, Otimar, Drotic, Cortomycin, AK-Spore HC Otic Suspension, Otocort Sterile Suspension, Masporin Otic, Cortatrigen Modified, Statrol, Antibiotic with Pramoxine, Neo-Poly-Bac, Cortomycin Eye Ointment, Terak, Neosporin Plus Maximum Strength, Neosporin Plus, Oti-Sone, Neotricin HC, Neosporin G U Irrigant, Ocu-Cort, Cort-Biotic, AK-Spore Ointment, Betadine Plus Antibiotic and Pain Reliever, Polytracin, Medi-Quik, Campho-Phenique Maximum Strength, NPD Ophthalmic Ointment, Duospore, NEO TO GO!, Triple Antibiotic Plus, Spectrocin Plus, Lanabiotic, Polycin-B, Dexasporin, Methadex, AK-Spore, Neocidin Ophthalmic Solution, Neosporin + Pain Relief Neo to Go!, Cortomycin Suspension, Neo/PolyB/HC, Ocu-Spore-G, Neoptic, AK-Trol, Ocu-Trol, Ocutricin, Neocin-PG, Neocidin

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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