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Polymyxin B use while Breastfeeding

Drugs containing Polymyxin B: Neosporin, Cortisporin Otic, Polytrim, Maxitrol, Polysporin, Triple Antibiotic, Cortisporin Ophthalmic Suspension, Antibiotic Plus Pain Relief, Neosporin Ophthalmic Ointment, Neo-Poly-Dex, Show all 85 »Terramycin with Polymyxin B Sulfate, Antibiotic Ear, Polysporin Ointment, Polysporin Ophthalmic, Cortatrigen, Neosporin Ophthalmic, Cortisporin Ointment, Dexacine, Cortisporin Ophthalmic Ointment, Cortisporin Cream, Otobiotic, Antibiotic with Pramoxine, Polycin-B, Betadine Antibiotic, Ophthocort, Ocu-Trol, AK-Poly-Bac, Drotic, Pediotic, AK-Spore, Dexacidin, Triple Antibiotic Plus, Mycitracin Plus Pain Reliever, Mycitracin Triple Antibiotic, Triple Antibiotic Ophthalmic Ointment, Polytracin Ophthalmic, Lanabiotic, Neotricin HC, Triple Antibiotic HC Ophthalmic Ointment, Cortatrigen Modified, Otimar, Otocort Sterile Suspension, Otocort Sterile Solution, Masporin Otic, Cortomycin, UAD Otic, Neocidin, AK-Spore HC Otic Suspension, Ocu-Cort, Neosporin Plus, Neosporin Plus Maximum Strength, Poly Pred, Terak, Cortomycin Eye Ointment, Neo-Poly-Bac, Oti-Sone, AK-Spore Ointment, Statrol, Neosporin G U Irrigant, Cort-Biotic, Neo/PolyB/HC, Campho-Phenique Maximum Strength, NEO TO GO!, Tribiotic Plus, NPD Ophthalmic Ointment, Dexasporin, Betadine Plus Antibiotic and Pain Reliever, Polytracin, Neosporin Plus Maximum Strength Ointment, Neosporin + Pain Relief Neo to Go!, Spectrocin Plus, Duospore, Methadex, AK-Trol, Neocidin Ophthalmic Solution, Cortomycin Suspension, Ocu-Spore-B, Neocin, Ocu-Spore-G, Neoptic, Poly-Dex, Medi-Quik, Septa, Neocin-PG, Ocutricin

Polymyxin B Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Clindamycin, Mupirocin

References

1. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Polymyxin B Identification

Substance Name

Polymyxin B

CAS Registry Number

1404-26-8

Drug Class

Antiinfective Agents, Local

Antibacterial Agents

Administrative Information

LactMed Record Number

550

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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