Octreotide use while Breastfeeding

Drugs containing Octreotide: Sandostatin, Sandostatin LAR Depot

Octreotide Levels and Effects while Breastfeeding

Summary of Use during Lactation

The excretion of octreotide into breastmilk has not been studied. However, because it is poorly absorbed orally and has been safely administered directly to infants by injection, it is unlikely to adversely affect the breastfed infant. One breastfed infant apparently experienced no adverse effects during maternal use of octreotide. Until more data are available, octreotide should be used in nursing mothers with careful infant monitoring, especially if the infant is under 2 months of age.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

One mother was treated for acromegaly during pregnancy and postpartum with octreotide (dose not stated). She breastfed (extent not stated) her infant for 4 months with no apparent problems noted in the infant.[1]

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

References

1. Colao A, Merola B, Ferone D, Lombardi G. Acromegaly. J Clin Endocrinol Metab. 1997;82:2777-81. PMID: 9284694

Octreotide Identification

Substance Name

Octreotide

CAS Registry Number

83150-76-9

Drug Class

Antineoplastic Agents, Hormonal

Gastrointestinal Agents

Administrative Information

LactMed Record Number

818

Last Revision Date

20130907

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