Norepinephrine use while Breastfeeding

Drugs containing Norepinephrine: Levophed, Levophed Bitartrate

Norepinephrine Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the use of norepinephrine during breastfeeding. Because of its poor oral bioavailability and short half-life, any norepinephrine in milk is unlikely to affect the infant. High intravenous doses of norepinephrine might reduce milk production or milk letdown.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Relevant published information in nursing mothers was not found as of the revision date. Animal data indicate that norepinephrine can decrease serum prolactin and reduce milk production.[1] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

References

1. Thomas GB, Cummins JT, Doughton BW et al. Direct pituitary inhibition of prolactin secretion by dopamine and noradrenaline in sheep. J Endocrinol. 1989;123:393-402. PMID: 2607250

Norepinephrine Identification

Substance Name

Norepinephrine

CAS Registry Number

51-41-2

Drug Class

  • Adrenergic Agonists
  • Adrenergic Alpha-Agonists
  • Catecholamines
  • Sympathomimetics
  • Vasoconstrictor Agents

Administrative Information

LactMed Record Number

779

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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