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Neomycin use while Breastfeeding

Drugs containing Neomycin: Neosporin, Cortisporin Otic, Maxitrol, Triple Antibiotic, Cortisporin-TC, Antibiotic Plus Pain Relief, Cortisporin Ophthalmic Suspension, Neosporin Ophthalmic Ointment, Cortatrigen, Antibiotic Ear, Show all 85 »Neo-Poly-Dex, Cortisporin Ointment, Septa, Dexacidin, Neosporin G U Irrigant, Triple Antibiotic HC Ophthalmic Ointment, Neosporin Ophthalmic, Neosporin + Pain Relief Neo to Go!, Myciguent, Cortisporin Cream, Neosporin Plus Maximum Strength Ointment, Coly-Mycin S, Triple Antibiotic Plus, Dexasporin, Neosporin Plus Maximum Strength, Neo-Fradin, Poly-Dex, Neo-Poly-Bac, Cortomycin Eye Ointment, Lanabiotic, Mycitracin Plus Pain Reliever, Mycitracin Triple Antibiotic, Cortatrigen Modified, Otimar, Pediotic, Otocort Sterile Suspension, Otocort Sterile Solution, AK-Spore HC Otic Suspension, First Aid Triple Antibiotic with Pain Reliever, Neocidin, Cortomycin, UAD Otic, Drotic, Masporin Otic, ProCoMycin, Ocu-Cort, Statrol, Neosporin Plus, Antibiotic with Pramoxine, Poly Pred, Neotricin HC, Neo-Tab, Oti-Sone, Triple Antibiotic Ophthalmic Ointment, Cortisporin Ophthalmic Ointment, Mycifradin, Cort-Biotic, AK-Spore Ointment, Neo-Decadron Cream, Neo-Dexair, Medi-Quik, Ocu-Spore-B, Neocin, Neo-Dex, AK-Neo-Dex, NEO TO GO!, Spectrocin Plus, Tribiotic Plus, Neo-Decadron, Neo-Decadron Ocumeter, Campho-Phenique Maximum Strength, NPD Ophthalmic Ointment, Ocu-Spore-G, Neoptic, Neocidin Ophthalmic Solution, AK-Spore, Cortomycin Suspension, Neocin-PG, Ocutricin, AK-Trol, Methadex, Dexacine, Ocu-Trol, Neo-Synalar, Neo/PolyB/HC

Neomycin Levels and Effects while Breastfeeding

Summary of Use during Lactation

Although no information exists on the excretion of neomycin into milk, other aminoglycoside antibiotics are poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of aminoglycosides, but serum levels are far below those attained when treating newborn infections and systemic effects of neomycin are unlikely. Older infants would be expected to absorb even less neomycin. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis.

Oral, topical, ophthalmic or otic neomycin should result in very low levels in breastmilk and present negligible risk to the infant,[1][2] although topical application to the nipple may increase the risk of diarrhea in the infant. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

(Injection) Gentamicin, Kanamycin, Tobramycin, (Topical) Bacitracin, Clindamycin, Mupirocin, Polymyxin B

References

1. Niebyl JR. Use of antibiotics for ear, nose, and throat disorders in pregnancy and lactation. Am J Otolaryngol. 1992;13:187-92. PMID: 1503194

2. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006;24:167-97. PMID: 16677965

3. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Neomycin Identification

Substance Name

Neomycin

CAS Registry Number

1404-04-2

Drug Class

Antiinfective Agents

Antibacterial Agents

Aminoglycosides

Dermatologic Agents

Administrative Information

LactMed Record Number

197

Last Revision Date

20150310

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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