Metolazone use while Breastfeeding
Drugs containing Metolazone: Zaroxolyn, Mykrox
Metolazone Levels and Effects while Breastfeeding
Summary of Use during Lactation
If metolazone is required by the mother, it is not a reason to discontinue breastfeeding. Intense diuresis with large doses may decrease breastmilk production.
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information on metolazone was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation. The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.
Alternate Drugs to Consider
1. Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;277:1353-4.
2. Reiher KH. [Suppression of lactation by stimulation of diuresis]. Zentralbl Gynakol. 1963;85:188-90. PMID: 13973786
3. Stout G. Suppression of lactation. Br Med J. 1962;1:1150. Letter. PMC: PMC1958377
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Last Revision Date
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.