Metolazone use while Breastfeeding

Drugs containing Metolazone: Zaroxolyn, Mykrox

Metolazone Levels and Effects while Breastfeeding

Summary of Use during Lactation

If metolazone is required by the mother, it is not a reason to discontinue breastfeeding. Intense diuresis with large doses may decrease breastmilk production.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Relevant published information on metolazone was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation.[1][2][3] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.

Alternate Drugs to Consider

Chlorothiazide, Hydrochlorothiazide

References

1. Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;277:1353-4.

2. Reiher KH. [Suppression of lactation by stimulation of diuresis]. Zentralbl Gynakol. 1963;85:188-90. PMID: 13973786

3. Stout G. Suppression of lactation. Br Med J. 1962;1:1150. Letter. PMC: PMC1958377

Metolazone Identification

Substance Name

Metolazone

CAS Registry Number

17560-51-9

Drug Class

• Antihypertensive Agents
• Thiazide Diuretics

Administrative Information

LactMed Record Number

181

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-01-24

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

• Metolazone use during Pregnancy
• Metolazone Consumer Information
• Breastfeeding Support Group
• Safe Medications during Breastfeeding
• Medicine use while Breastfeeding
• Medicine use during Pregnancy

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