Magnesium Hydroxide use while Breastfeeding

Drugs containing Magnesium Hydroxide: Maalox, Milk of Magnesia, Mylanta, Phillips' Milk of Magnesia, Maalox Plus, Mintox, Maalox Advanced Maximum Strength, Pepcid Complete, Maalox Max, Gelusil, Show all 81 »Rolaids Regular Strength, Mi-Acid, Rolaids Extra Strength, Maldroxal, Milantex, Arthritis Pain Formula, Almacone, Alamag, Dulcolax Milk of Magnesia, Ex-Lax Milk of Magnesia, Almacone-2, Mylanta Ultra, Dual Action Complete, Mylanta Supreme, Di-Gel, Rulox, Mylanta Maximum Strength Cherry, Pedia-Lax Chewable Tablets, Acid Reducer + Antacid Dual Action, Maalox Antacid Antigas Regular Strength, Maalox TC, Aldroxicon I, FIRST Mouthwash BLM, Masanti DS, Alamag Plus, Magaant, Mintox Plus, Phillips' Haleys M-O, Tums Dual Action, Maalox Max Wild Berry, Mylanta Maximum Strength, Zegerid with Magnesium Hydroxide, Haley's M-O, Acid Controller Complete Dual Action, Mi-Acid Double Strength, Advanced Formula Di-Gel, Di-Gel Mint, Mintox Maximum Strength, Rolaids Multi-Symptom, Masanti Supreme, Di-Gel Lemon, Mylanta Gelcap, Fast Acting Mylanta, Mi-Acid II, Mylanta Ultimate Strength, Mintox Tablets, Maalox Advanced Regular Strength, Flanax Antacid Liquid, Milantex Maximum Strength, Maalox HRF, Rulox 1, Aspirin Buffered, Magnaprin, Aspir-Mox, Aspir-Mox IB, ConRx AR, Mylanta Fast Acting, Mylanta DS Fast Acting, Maldroxal Plus, Urban DS, Maalox Plus Extra Strength, Aldroxicon II, Tempo, Urban, Uni-Lan II, Mylagen, Masanti, Mylagen-II, Rulox Plus, Uni-Lan, Mintox Extra Strength

Magnesium Hydroxide Levels and Effects while Breastfeeding

Summary of Use during Lactation

A study on the use of magnesium hydroxide during breastfeeding found no adverse reactions in breastfed infants. Intravenous magnesium increases milk magnesium concentrations only slightly. Oral absorption of magnesium by the infant is poor, so maternal magnesium hydroxide is not expected to affect the breastfed infant's serum magnesium. Magnesium hydroxide can be taken during breastfeeding and no special precautions are required.

Drug Levels

Maternal Levels. Ten women with pre-eclampsia were given 4 grams of magnesium sulfate intravenously followed by 1 gram per hour until 24 hours after delivery. While the average serum magnesium was 35.5 mg/L in treated women compared to 18.2 mg/L in 5 untreated controls, colostrum magnesium levels at the time of discontinuation of the infusion was 64 mg/L in treated women and 48 mg/L in the controls. By 48 hours after discontinuation, colostrum magnesium levels were only slightly above control values and by 72 hours they were virtually identical to controls.[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Fifty mothers who were in the first day postpartum received 15 mL of either mineral oil or an emulsion of mineral oil and magnesium hydroxide equivalent to 900 mg of magnesium hydroxide, although the exact number who received each product was not stated. Additional doses were given on subsequent days if needed. None of the breastfed infants were noted to have any markedly abnormal stools, but all of the infants also received supplemental feedings.[2]

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Bisacodyl, Docusate, Psyllium, Sodium Picosulfate, Sodium Phosphate

References

1. Cruikshank DP, Varner MW, Pitkin RM. Breast milk magnesium and calcium concentrations following magnesium sulfate treatment. Am J Obstet Gynecol. 1982;143:685-8. PMID: 7091241

2. Baldwin WF. Clinical study of senna administration to nursing mothers. Can Med Assoc J. 1963;89:566-7.

Magnesium Hydroxide Identification

Substance Name

Magnesium Hydroxide

CAS Registry Number

1309-42-8

Drug Class

Antacids

Cathartics

Gastrointestinal Agents

Magnesium Compounds

Administrative Information

LactMed Record Number

463

Last Revision Date

20130907

Disclaimer

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