Magnesium Hydroxide use while Breastfeeding

Drugs containing Magnesium Hydroxide: Maalox, Mylanta, Milk of Magnesia, Phillips' Milk of Magnesia, Maalox Plus, Mintox, Pepcid Complete, Maalox Antacid Antigas Regular Strength, Almacone, Rulox, Show all 81 »Maalox Advanced Maximum Strength, Rolaids Regular Strength, Gelusil, Mi-Acid, Dulcolax Milk of Magnesia, Alamag, Rolaids Extra Strength, Acid Reducer + Antacid Dual Action, Aspirin Buffered, Maalox Max, Arthritis Pain Formula, Tempo, Flanax Antacid Liquid, Mylanta Gelcap, Haley's M-O, Dual Action Complete, Mylanta Ultra, Maalox Plus Extra Strength, Mylanta Supreme, Magaant, Maldroxal, Ex-Lax Milk of Magnesia, Di-Gel Lemon, Zegerid with Magnesium Hydroxide, Milantex, Mintox Maximum Strength, Mylanta Maximum Strength, Mylanta Maximum Strength Cherry, Maalox Max Wild Berry, Tums Dual Action, Acid Controller Complete Dual Action, Fast Acting Mylanta, Mi-Acid Double Strength, Rolaids Multi-Symptom, Masanti Supreme, Di-Gel Mint, Advanced Formula Di-Gel, Pedia-Lax Chewable Tablets, Mintox Extra Strength, Phillips' Haleys M-O, Mylagen-II, ConRx AR, Mintox Tablets, Milantex Maximum Strength, Maalox Advanced Regular Strength, Mylanta DS Fast Acting, Mylanta Fast Acting, Maalox TC, Rulox 1, Aspir-Mox, Magnaprin, Aspir-Mox IB, FIRST Mouthwash BLM, Mylanta Ultimate Strength, Maalox HRF, Masanti DS, Masanti, Uni-Lan II, Uni-Lan, Urban, Urban DS, Aldroxicon I, Maldroxal Plus, Di-Gel, Rulox Plus, Mi-Acid II, Alamag Plus, Almacone-2, Mintox Plus, Mylagen, Aldroxicon II

Magnesium Hydroxide Levels and Effects while Breastfeeding

Summary of Use during Lactation

A study on the use of magnesium hydroxide during breastfeeding found no adverse reactions in breastfed infants. Intravenous magnesium increases milk magnesium concentrations only slightly. Oral absorption of magnesium by the infant is poor, so maternal magnesium hydroxide is not expected to affect the breastfed infant's serum magnesium. Magnesium hydroxide can be taken during breastfeeding and no special precautions are required.

Drug Levels

Maternal Levels. Ten women with pre-eclampsia were given 4 grams of magnesium sulfate intravenously followed by 1 gram per hour until 24 hours after delivery. While the average serum magnesium was 35.5 mg/L in treated women compared to 18.2 mg/L in 5 untreated controls, colostrum magnesium levels at the time of discontinuation of the infusion was 64 mg/L in treated women and 48 mg/L in the controls. By 48 hours after discontinuation, colostrum magnesium levels were only slightly above control values and by 72 hours they were virtually identical to controls.[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Fifty mothers who were in the first day postpartum received 15 mL of either mineral oil or an emulsion of mineral oil and magnesium hydroxide equivalent to 900 mg of magnesium hydroxide, although the exact number who received each product was not stated. Additional doses were given on subsequent days if needed. None of the breastfed infants were noted to have any markedly abnormal stools, but all of the infants also received supplemental feedings.[2]

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Bisacodyl, Docusate, Psyllium, Sodium Picosulfate, Sodium Phosphate

References

1. Cruikshank DP, Varner MW, Pitkin RM. Breast milk magnesium and calcium concentrations following magnesium sulfate treatment. Am J Obstet Gynecol. 1982;143:685-8. PMID: 7091241

2. Baldwin WF. Clinical study of senna administration to nursing mothers. Can Med Assoc J. 1963;89:566-7.

Magnesium Hydroxide Identification

Substance Name

Magnesium Hydroxide

CAS Registry Number

1309-42-8

Drug Class

Administrative Information

LactMed Record Number

463

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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