Loperamide use while Breastfeeding
Drugs containing Loperamide: Imodium, Imodium A-D, Anti-Diarrheal, Imodium Multi-Symptom Relief, Diamode, Pepto Diarrhea Control, Kaopectate 1-D, Up and Up Anti-Diarrheal Solution, Neo-Diaral, Imotil, Show all 13 »
Loperamide Levels and Effects while Breastfeeding
Summary of Use during Lactation
Use of loperamide during breastfeeding is unlikely to affect the infant.
Drug Levels
Maternal Levels. Loperamide has not been studied during breastfeeding, but the loperamide prodrug, loperamide oxide, has been studied in a dosage of 2 doses of 4 mg given 12 hours apart to 6 women 18 to 47 hours after delivery. Median loperamide milk concentrations were 0.18 mcg/L at 12 hours after the first dose, 0.27 mcg/L at 6 hours after the second dose, and 0.19 mcg/L at 24 hours after the second dose.[1]
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Possible Effects on Lactation
Relevant published information was not found as of the revision date.
References
1. Nikodem VC, Hofmeyr GJ. Secretion of the antidiarrhoeal agent loperamide oxide in breast milk. Eur J Clin Pharmacol. 1992;42:695-6. PMID: 1623917
Loperamide Identification
Substance Name
CAS Registry Number
53179-11-6
Drug Class
Administrative Information
LactMed Record Number
424
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
2010-12-07
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
See Also...
- Loperamide use during Pregnancy
- Loperamide Consumer Information
- Breastfeeding Support Group
- Safe Medications during Breastfeeding
- Medicine use while Breastfeeding
- Medicine use during Pregnancy
Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.
