Fosfomycin use while Breastfeeding

Drugs containing Fosfomycin: Monurol

Fosfomycin Levels and Effects while Breastfeeding

Summary of Use during Lactation

Limited information indicates that fosfomycin produces low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months.

Drug Levels

Maternal Levels. After 1 to 2 grams of fosfomycin given by injection, colostrum levels in 2 women were 4.8 mg/L and milk levels were 3.6 mg/L.[1][2] Further details of the studies were not given.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Nitrofurantoin, Norfloxacin, Trimethoprim

References

1. Gallego A, Rodriguez A, Mata A. Fosfomycin: pharmacological studies. Drugs Today (Barc). 1974;10 (Suppl):161-8.

2. Kirby WMM. Pharmacokinetics of fosfomycin. Chemotherapy. 1977;23 (Suppl 1):141-51. PMID: 832510

Fosfomycin Identification

Substance Name

Fosfomycin

CAS Registry Number

23155-02-4

Drug Class

Antibacterial Agents

Antiinfective Agents, Urinary

Administrative Information

LactMed Record Number

478

Last Revision Date

20130907

Disclaimer

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Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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