Dyphylline use while Breastfeeding

Drugs containing Dyphylline: COPD, Dilor, Dilex-G 400, Lufyllin, Dy-G, Dyflex-G, Dyphylline GG ES, Dilor-G, Panfil G, LGG, Show all 27 »Dyfilin GG, D-G, Dyline GG, Dilex-G 200, Jay-Phyl, Dyphyllin-GG, Dyphyl GG, Dilor-400, Lufyllin-400, Neothylline, Dylix, Lufyllin-EPG, Lufyllin-GG, Difil G, Dyphylline GG, Dilex-G, Difil-G Forte

Dyphylline Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because of the relatively high levels in milk and a previous report with theophylline, occasional stimulant effects in infants should be anticipated in breastfed infants. No severe adverse reactions are expected. Amounts in milk can be minimized by avoiding breastfeeding for 3 to 4 hours after a dose.

Drug Levels

Maternal Levels. After intramuscular administration of a single 5 mg/kg dose of dyphylline, peak milk levels usually occurred between 2 and 4 hours after the dose in 20 subjects. Peak milk levels averaged 24.3 mg/L.[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Albuterol, Aminophylline, Theophylline

References

1. Jarboe CH, Cook LN, Malesic I, Fleischaker J. Dyphylline elimination kinetics in lactating women: blood to milk transfer. J Clin Pharmacol. 1981;21:405-10. PMID: 7309903

Dyphylline Identification

Substance Name

Dyphylline

CAS Registry Number

479-18-5

Drug Class

Administrative Information

LactMed Record Number

590

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

Hide
(web5)