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Docusate use while Breastfeeding

Drugs containing Docusate: Colace, Doc-Q-Lace, Senna Plus, Dulcolax Stool Softener, Senna S, Surfak, DOK, Senokot S, DSS, Peri-Colace, Show all 102 »Doculase, Senexon-S, Enemeez Mini, Phillips Stool Softener, Doc-Q-Lax, Laxacin, Doculax, Dok Plus, Sennalax-S, Silace, Docu, Docuprene, Colace Micro-Enema, Promolaxin, Fleet Sof-Lax Stool Softener, Doss-Relief, Dionex, Kao-Tin, DocuSol, Correctol Softgel Extra Gentle, Dioctyn, Docusil, DocuSol Kids, Ferrous DS, Ferro-Sequels (old formulation), Enemeez Plus, Dioeze, Diocto, Perestan, DOS, Surfak Stool Softener, Ferocyl, Ferro-Caps, Ferro Basic, Phillips Gel, Fe-Stool, Vacuant, Kaopectate Stool Softener, Sulfolax, Pedia-Lax Stool Softener, Pedia-Lax Liquid Stool Softener, Ferro-DSS, Modane Plus, Dialose Plus, Octycine-250, Gentlax S, Ex-Lax Gentle Strength, SenoSol-SS, Femintrol, Feminine Lax, Unilax, Docucal-P, Doxidan Softgel Laxative Plus Stool Softener, Femilax, Ex-Lax Extra Gentle, Modane Soft, DSS Plus, DSMC Compound Plain, Aqualax Forte, Genasoft Plus, Peri-DOS, Doculax Plus, Strong Caps, Peri-DS, Octycine, Docu Soft Plus, Therevac Plus, Vacuant Plus, Docusol Plus, Doxidan, Diocto-C, Diocto-K Plus, Dioctolose, Dialose, DC-240, D-S Caps, Calube, Calcium Stool Softener, Ex-Lax Stool Softener, Genasoft, Therevac-SB, Sur-Q-Lax, Docusoft S, Docucal, Regulax SS, Sulfalax Calcium, Kasof, Aqualax, Dioctocal, Docu Soft, Dioctosoftez, Octycine-100

Docusate Levels and Effects while Breastfeeding

Summary of Use during Lactation

Docusate is minimally absorbed from the gastrointestinal tract and therefore the drug is unlikely to be found in the maternal serum or breastmilk. Laxatives that are completely unabsorbed may be preferred.[2]

Drug Levels

Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

In a randomized, blinded trial, 35 postpartum breastfeeding patients received a laxative containing docusate in a dose of 120 mg daily in addition to danthron 100 mg daily. One patient stated that diarrhea occurred in her breastfed infant.[1] The diarrhea was most likely caused by the danthron.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Bisacodyl, Magnesium Hydroxide, Psyllium, Senna

References

1. Greenhalf JO, Leonard HS. Laxatives in the treatment of constipation in pregnant and breast-feeding mothers. Practitioner. 1973;210:259-63. PMID: 4570522

2. Lewis JH, Weingold AB and the Committee of FDA-Related Matters, American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912-23. PMID: 2864852

Docusate Identification

Substance Name

Docusate

CAS Registry Number

10041-19-7

Drug Class

Gastrointestinal Agents

Laxatives

Surface-Active Agents

Administrative Information

LactMed Record Number

456

Last Revision Date

20130907

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