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Clotrimazole use while Breastfeeding

Drugs containing Clotrimazole: Lotrisone, Canesten, Mycelex, Lotrimin AF Athlete's Foot Cream, Mycelex Troche, Clotrimazole Troche, Lotrimin AF Jock Itch Cream, Clotrimazole-7, Gyne-Lotrimin, Clotrimazole-3, Show all 21 »Desenex Antifungal Cream, Lotrimin AF For Her Athlete's Foot Cream, Mycelex OTC, Femcare, Canesten 6 Day Pessary, Gyne-Lotrimin 3 Day, FungiCURE Pump Spray, Canesten 3, Abtrim, Abtrim Pessaries, Canesten 1

Clotrimazole Levels and Effects while Breastfeeding

Summary of Use during Lactation

Because clotrimazole has poor oral bioavailability, it is unlikely to adversely affect the breastfed infant, including topical application to the nipples. It has been used orally in infants with thrush, sometimes successfully after nystatin has failed.[1] Any excess cream or ointment should be removed from the nipples before nursing. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Fluconazole, Miconazole, Nystatin

References

1. Johnstone HA, Marcinak JF. Candidiasis in the breastfeeding mother and infant. J Obstet Gynecol Neonatal Nurs. 1990;19:171-3. PMID: 2319366

2. Noti A, Grob K, Biedermann M et al. Exposure of babies to C(15)-C(45) mineral paraffins from human milk and breast salves. Regul Toxicol Pharmacol. 2003;38:317-25. PMID: 14623482

Clotrimazole Identification

Substance Name

Clotrimazole

CAS Registry Number

23593-75-1

Drug Class

  • Antifungal Agents

Administrative Information

LactMed Record Number

346

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

See Also...

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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