Cascara Sagrada use while Breastfeeding
Drugs containing Cascara Sagrada: Caroid Laxative, Natures Remedy
Cascara Sagrada Levels and Effects while Breastfeeding
Summary of Use during Lactation
Maternal cascara intake might cause loose stools in some breastfed infants and should be avoided. Other laxatives are preferred.
After administration of 65 mg of cascara sagrada as cascara fluidextract, cascara was qualitatively detected in the breastmilk of 5 of 10 women collected over 20 hours. The sensitivity of the assay was about 1100 mg/L of cascara.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
In 2 uncontrolled studies, a total of 10 of 22 breastfed neonates appeared to have loose stools after administration of 65 mg of cascara as cascara fluidextract to their mothers.
In an observational case series, no cases of diarrhea were observed among the breastfed infants of 142 mothers who received 400 mg of cascara extract on day 3 postpartum. This result might have been because of the small amount of colostrum received by the infants of this age.
Possible Effects on Lactation
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
1. Lewis JH, Weingold AB and the Committee of FDA-Related Matters, American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912-23. PMID: 2864852
2. Tyson RM, Shrader EA, Perlman HH. Drugs transmitted through breast milk. Part I: laxatives. J Pediatr. 1937;11:824-32.
3. Duncan AS. Standardized senna as a laxative in the puerperium. A clinical assessment. Br Med J. 1957;1:439-41. PMID: 13396280
Cascara Sagrada Identification
CAS Registry Number
- Gastrointestinal Agents
LactMed Record Number
Information from the National Library of Medicine's LactMed Database.
Last Revision Date
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