Bendroflumethiazide use while Breastfeeding

Drugs containing Bendroflumethiazide: Corzide, Rauzide, Rondameth, Flumezide, Corzide 80/5, Corzide 40/5, Naturetin-5, Naturetin-10, Naturetin

Bendroflumethiazide Levels and Effects while Breastfeeding

Summary of Use during Lactation

If bendroflumethiazide is required by the mother, it is not a reason to discontinue breastfeeding. Intense diuresis with large doses of bendroflumethiazide can decrease breastmilk production, especially during the neonatal period. Shorter-acting diuretics in low doses are preferred over bendroflumethiazide.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Possible Effects on Lactation

Bendroflumethiazide has been used to suppress lactation in oral doses of 5 mg twice daily for 5 days,[1] and in doses of 10 mg in the morning and 5 mg in the afternoon.[2] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of potent diuretics on established, ongoing lactation.

Alternate Drugs to Consider

Chlorothiazide, Hydrochlorothiazide

References

1. Healy M. Suppressing lactation with oral diuretics. Lancet. 61;1:1353-4.

2. Stout G. Suppression of lactation. Br Med J. 62;1:1150. Letter. PMC: PMC1958377

Bendroflumethiazide Identification

Substance Name

Bendroflumethiazide

CAS Registry Number

73-48-3

Drug Class

Administrative Information

LactMed Record Number

27

Information from the National Library of Medicine's LactMed Database.

Last Revision Date

2013-09-07

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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