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Acesulfame use while Breastfeeding

Acesulfame Levels and Effects while Breastfeeding

Summary of Use during Lactation

No well-controlled data are available on the extent of passage of acesulfame into breastmilk. However, acesulfame has been found in variable concentrations in the breastmilk of nursing mothers who report consuming artificially sweetened beverages and sweetener packets in the past 24 hours. Even some mothers who reported not consuming artificial sweeteners have small amounts of acesulfame in their breastmilk. Some authors suggest that women may wish to limit the consumption of nonnutritive sweeteners while breastfeeding because their effect on the nursing infants are unknown.[1]

Drug Levels

Maternal Levels. Twenty lactating women completed background questionnaires about breastfeeding and the intake of nonnutritive sweeteners in the prior 24 hours. Each then donated a milk sample that was analyzed for the presence of nonnutritive sweeteners. Sweetener intake was primarily from diet sodas and sweetener packets. Of the 14 women who reported intake of a nonnutritive sweetener, 9 had acesulfame detectable in their breastmilk in concentrations ranging from 0.01 to 2.22 mg/L. In addition, 4 of the 6 women reporting no nonnutritive sweetener intake also had milk acesulfame levels ranging from 0.02 to 0.09 mg/L, probably from hidden sources in food.[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Aspartame, Saccharin, Sucralose

References

1. Sylvetsky AC, Gardner AL, Bauman V et al. Nonnutritive sweeteners in breast milk. J Toxicol Environ Health A. 2015;78:1029-32. PMID: 26267522

Acesulfame Identification

Substance Name

Acesulfame

CAS Registry Number

33665-90-6

Drug Class

Artificial Sweeteners

Sweetening Agents

Administrative Information

LactMed Record Number

632

Last Revision Date

20151001

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

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