Abatacept use while Breastfeeding

Drugs containing Abatacept: Orencia

Abatacept Levels and Effects while Breastfeeding

Summary of Use during Lactation

Abatacept is a large protein molecule with a molecular weight of 92,000. Only small amounts at most would be expected to enter breastmilk. No information is available on the use of abatacept during breastfeeding, so an alternate drug may be preferred, especially while nursing a newborn or preterm infant.[1][2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

(Rheumatoid Arthritis) Auranofin, Gold Sodium Thiomalate, Hydroxychloroquine, Infliximab, Methotrexate, Penicillamine, Sulfasalazine

References

1. Ostensen M. Management of early aggressive rheumatoid arthritis during pregnancy and lactation. Expert Opin Pharmacother. 2009;10:1469-79. PMID: 19505214

2. Keeling SO, Oswald AE. Pregnancy and rheumatic disease: "by the book" or "by the doc". Clin Rheumatol. 2009;28:1-9. PMID: 18987777

Abatacept Identification

Substance Name

Abatacept

CAS Registry Number

332348-12-6

Drug Class

Antirheumatic Agents

Administrative Information

LactMed Record Number

893

Last Revision Date

20130907

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Disclaimer: This information is not intended as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. Use of this website signifies your agreement to the Terms of Use and Online Privacy Policy.

Hide
(web4)