Generic Name: azithromycin ophthalmic (a ZITH roe MYE sin off THAL mik)
Brand Names: AzaSite

What is AzaSite?

AzaSite is an eye ointment containing azithromycin, a macrolide antibiotic that fights bacteria.

AzaSite is used to treat eye infections caused by bacteria.

AzaSite may also be used for purposes not listed in this medication guide.

Important information about AzaSite

You should not use AzaSite if you are allergic to azithromycin. Do not use this medication while wearing contact lenses. AzaSite may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using AzaSite before putting your contact lenses in.

You should not wear contact lenses while you still have active symptoms of the eye infection you are treating.

Slideshow: 10 Things to Know About Antibiotic Resistance

Use AzaSite for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Serious side effects of AzaSite may include eye drainage or crusting, severe eye irritation, feeling like there is something in your eye, watery eyes, increased light sensitivity, eye redness or swelling, any signs of new infection.

Although the risk of serious side effects is low when AzaSite is used in the eyes, side effects can occur if the medicine is absorbed into your bloodstream. Stop using the medicine and get emergency medical help if you have any signs of a severe skin reaction, such as fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Before taking AzaSite

You should not use AzaSite if you are allergic to azithromycin (Zithromax).

FDA pregnancy category B. AzaSite is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether azithromycin passes into breast milk or if it could harm a nursing baby. Do not use AzaSite without telling your doctor if you are breast-feeding a baby.

See also: AzaSite pregnancy and breastfeeding warnings (in more detail)

How should I use AzaSite?

Use AzaSite exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

AzaSite is usually applied twice daily for 2 days, and then once daily for 5 more days. Wash your hands before using eye medication. Follow your doctor's instructions.

To apply the eye drops:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye.

• Use only the number of drops your doctor has prescribed.

• Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct.

• If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.

• Also wait at least 10 minutes before using any other eye drops that your doctor has prescribed.

Do not allow the tip of the dropper to touch any surface, including your eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.

Use AzaSite for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared.

Store an unopened bottle of AzaSite in the refrigerator. Do not freeze. After opening the bottle, you may keep the medication at room temperature for up to 14 days. Keep the bottle tightly closed when not in use. Protect from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking AzaSite?

Do not use this medication while wearing contact lenses. AzaSite may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using AzaSite before putting your contact lenses in.

You should not wear contact lenses while you still have active symptoms of the eye infection you are treating.

AzaSite side effects

Get emergency medical help if you have any of these signs of an allergic reaction to AzaSite: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when AzaSite is used in the eyes, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.

Stop using the medicine and get emergency medical help if you have any signs of a severe skin reaction, such as:

• fever, sore throat;

• swelling in your face or tongue, burning in your eyes; or

• skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Stop using AzaSite and call your doctor at once if you have a serious side effect such as:

• drainage or crusting of your eye;

• severe burning, stinging, itching, or other irritation after using the eye drops;

• feeling like there is something in your eye;

• watery eyes, increased light sensitivity;

• eye redness or swelling; or

• any signs of a new infection.

Less serious AzaSite side effects may include:

• blurred vision;

• stuffy nose; or

• mild stinging, burning, or irritation of your eyes.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

See also: AzaSite side effects (in more detail)

What other drugs will affect AzaSite?

It is not likely that other drugs you take orally or inject will have an effect on AzaSite used in the eyes. But many drugs can interact with each other. Tell your doctor about all medicines you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about AzaSite.