Will Tysabri make me fat?

21 Sep 2011

Hi, first of all, well done on the weight loss! I wish i had your will power!
Ok, so weight gain is not listed as a known side effect of tysabri. Of course people can have side effects/reactions to a drug that have not yet been reported, but i would say you are at a very low risk of gaining weight because of this med.

26 Sep 2011

Well I started on Tysabri in February this year and I have gained nearly 40lb. I had previously lost a lot of weight - about 30lb (without trying) when I was on Rebif, and had kept it off for a couple of years. I now weigh more than when I was 9 months pregnant. My diet and exercise levels haven't changed over the period. I have also been on antidepressants so it might be something to do with that. Or it might be to do with stopping Rebif. The upside is that I feel much better on Tysabri but the weight gain really gets me down.