Why does the advil gelcap bottle label states not to drink alcohol at least 3 times?please clarify the reasons why? NSAIDs with alcohol should not be mixed.
30 Jul 2011
The following interaction exists for Advil with NSAIDs:
ibuprofen ↔ ethanol
Applies to: Advil (ibuprofen), Alcohol (contained in alcoholic beverages) (ethanol)
GENERALLY AVOID: The concurrent use of aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) and ethanol may lead to gastrointestinal (GI) blood loss. The mechanism may be due to a combined local effect as well as inhibition of prostaglandins leading to decreased integrity of the GI lining.
MANAGEMENT: Patients should be counseled on this potential interaction and advised to refrain from alcohol consumption while taking aspirin or NSAIDs.
So it can lead to bleeding in the stomach and/or intestines.
Hope this helps,
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