... patient with Gemtuzumab?
When running liver function what levels of ALT and AST should we be concerned with when treating a?
- Posted:
- 6 Feb 2010 by Ammanuel
- Topics:
- acute myeloid leukemia, gemtuzumab
Details:
Added 6 Feb 2010:
When treating AML with Gemtuzumab what levels of ALT and AST should we be more concerned with?
Answers (1)
suzanne6615 Feb 2010
Common liver function tests usually involve the investigations of Transferases - usually either Alanine aminotransferase (ALT) or Aspartate aminotransferase (AST).
These enzymes normally reside inside cells so raised levels usually represent hepatocellular (liver) damage. ALT is more specific to the liver, as AST is also found in cardiac and skeletal muscle and red blood cells.
Very high levels (>1000 IU/l) suggest drug induced hepatitis e.g. Gemtuzumab
Ask your doctor for more information.
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