When I was taking Elavil 25mg a day for migarine headache my headaches went away, now my Dr. is given me xanax 0.25 twice a day for anxiety and i am starting to have headaches again. Can i take these two drugs and still function through out the day?
5 Jun 2011
well the xaxax is for anxiety, i don't know why he would prescribe that with the elavil if it was working?
Here is some reading.
Interactions between your selected drugs
amitriptyline ↔ alprazolam
Applies to: Elavil (amitriptyline), Xanax (alprazolam)
MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.
MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Ambulatory patients should be counseled to avoid hazardous activities requiring mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
Other drugs that your selected drugs interact with
Elavil (amitriptyline) interacts with more than 500 other drugs.
Xanax (alprazolam) interacts with more than 300 other drugs.
Interactions between your selected drugs and food
alprazolam ↔ food
Applies to: Xanax (alprazolam)
GENERALLY AVOID: The pharmacologic activity of oral midazolam, triazolam, and alprazolam may be increased if taken after drinking grapefruit juice. The proposed mechanism is CYP450 3A4 enzyme inhibition.
MANAGEMENT: The manufacturer recommends that grapefruit juice should not be taken with oral midazolam. Patients taking triazolam or alprazolam should be monitored for excessive sedation. Alternatively, the patient could consume orange juice which does not interact with these drugs.
Hope this helps.
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