What is the role of phenol in Vi polysacchride vaccine against typhoid?

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29 Nov 2009

The typhoid vaccine is produced by heating a strain of salmonella typhi and then adding phenol, holding and then freeze drying the vaccine. This process inactivates the salmonella typhi strain.

The heat kills the salmonella and the phenol preserves it so that it can be reconstituted and given by injection when required.

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