Can you help me with the conversion of Oxycodone IR (5mg tab) to Hydrocodone/Apap 10/325mg tab? How much Oxycodone will I have to take to make an equal dose in Hydrocodone?
26 Nov 2011
7.5 mg of hydrocodone equals 5 mg of oxycodone. At least that's as close as you can get to equal analgesic dosage. Hydrocodone does metabolise into hydromorphone, which is what binds to the opiate receptors in the cns. Hydrocodone has no pharmacological action on its own. Oxycodone on the other hand, provides pharmacological action of its own. Oxycodone does metabolise into oxymorphone, but it is only a minor metabolite. Finally, as far as time release or whatever was brought up, neither the 5 mg formulation of oxycodone nor the 7.5 mg formulation of hydrocodone have a time release mechanism. If your going to take the time to answer questions, at least make sure your information is accurate.(sorry for the essay)
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