rhmsjsssCan you help me with the conversion of Oxycodone IR (5mg tab) to Hydrocodone/Apap 10/325mg tab? How much Oxycodone will I have to take to make an equal dose in Hydrocodone?
What is the dose conversion between Oxycodone and Hydrocodone?
- Posted:
- 21 Nov 2006 by rhmsjsss
- Topics:
- hydrocodone, oxycodone
Details:
Answers (4)
Cats Meow
oxyaaron
arcanoidcyst16
29 Mar 2011
Well it is different in my case because 2 of the 7.5mg vicoden work better in terms of pain relief than 2 of the 5mg oxycodone instant release and yes they still make those without the tylenol in it?I know it is very strange.I have been looking everywhere trying to find out why the vicoden seem stronger to me than the oxy and the only conclusion I have found is that.Once vicoden enters your liver it turns into hydromorphone.Which might I add is stronger than both hydrocodone and oxy put together.But like I said it is just a hypothesis.
danzana
2 Mar 2012
The oxy works alot faster,and gives you energy.On the other hand hydrocodone works longer and doesnt give you the speediness boost of energy that can be very addictive of which you feel with oxycodone.The strongest and cleanest cheapest form of pain meds is Morphine>We have built in receptors in our brains made just for Morphine
amylynn07431 Dec 2010
I can explain it to you without the extended release conversion. 7.5 mg of hydrocodone is equivalent to 5mg of oxycodone. The other difference with extended release tablets is the way it's absorbed in your body. The outer layer coating allows a pill to be released slower to last longer but the "pain relieving" effect should still equal the same pain relieving equivalent as I mentioned above. Good Luck to you, I hope that you feel better soon. I'm someone who suffers in chronic/continuous pain and is prescribed Percocet 10/325 for pain.
aslkdfjh26 Nov 2011
7.5 mg of hydrocodone equals 5 mg of oxycodone. At least that's as close as you can get to equal analgesic dosage. Hydrocodone does metabolise into hydromorphone, which is what binds to the opiate receptors in the cns. Hydrocodone has no pharmacological action on its own. Oxycodone on the other hand, provides pharmacological action of its own. Oxycodone does metabolise into oxymorphone, but it is only a minor metabolite. Finally, as far as time release or whatever was brought up, neither the 5 mg formulation of oxycodone nor the 7.5 mg formulation of hydrocodone have a time release mechanism. If your going to take the time to answer questions, at least make sure your information is accurate.(sorry for the essay)
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above^ is wrong. oxycodone is roughly 1.5-2 times stronger then hydrocodone. most would say 5mg hydrocodone would be equal to 7.5mg oxycodone.
Don't ya just love know it alls?
Yes, especially when he doesn't know what he's talking about. Oxy is 1.5-2 times stronger then morphine, not hydrocodone.
My answer was correct, but a little on the high side, but within published equalivancies, its actually closer to 10mgs.
hrmmm... if Oxy is 1.5 times stronger, than 5mg of Oxy would roughly have the same effect as 7.5mg of Hydro. Not the reverse.
Best,
Mike
*than* should have been *then*
If no one is willing to do the kind of research that people like Maso do and then give a proper and definite answer that is correct, why answer at all? People need to get their research right before posting answers, if i don't know something for certain, i don't post it. Everyone should be the same in that dept., let's not confuse people looking for answers.
and this was the answer i was speaking of, meant to point that out.
Not Mike's the other that was "a little off in the figuring" can't afford to be "off" in our figures when it comes to people taking drugs. Sorry guys but this pisses me off.
one more thing: is someone here confusing oxycodone with oxycontin?
Not the same drug. Comparisons to morphine can be made with contin, not usually done with codone.
It is the same drug! Oxycontin is just oxycodone extended release. Comparisons can be made with any drug (in the same class), they have to be, that's how doctors are able to titrate their patients when Rx'ing one drug to another.
I take oxycodone and I had been on hydros. The oxycodone is stronger and will help you more.
Hi, I just like to post this accurate information. You can find it youself at differecebetween.net. Whatever u do is ur buisness as long as u aint hurting nobody... Take care everbody-
•Oxycodone hydrochloride is an opioid painkiller. It can be found in a number of prescription medications. When it is available by itself, it is available in the form of oxycontin. Oxycodone is also found in combination with other ingredients on a number of prescription medications e.g. Percocet.
•The main difference between the two relates to the onset of action. Oxycontin is a time released drug. This means that it acts over a period of time. Usually, oxycodone medications need to be taken every four to six hours. However, Oxycontin continues acting for at least 12 hours. That is why it needs to be taken only twice a day.
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You may come across certain articles that categorize oxycodone as a generic name for oxycontin because it is the active substance in the medication. However, it would be incorrect to say that because oxycodone is an active ingredient in other medications also. Most experts prefer calling oxycontin ‘oxycodone extended release’
THANK YOU "research first". I believe you have given the exact information I was looking for. Again, thank you.
Research,
Your answer makes good sense but its off the topic of which drug is stronger Hydro ( vicodin) vs Oxycodone ( or oxy based products)
I believe it is generally agreed that Oxycodone is stronger than Hydrocodone probably by 1.5 times is a fair guess but the biggest difference between the 2 are in the physics makeup of the two which is quite complicated
you have it backwards. 5mg hydro = 7.5mg oxy
Wish it were so easy to determine equivalent dosing. There is significant variation in Kappa and mu opiod receptor concentrations in a population. Oxycodone tends to bind Kappa to a greater degree than hydrocodone.. also bioavailability is different for each depending on my factors unique to the individual. but it is generally agreed that oxycodone is 1.5 to 2x more potent on average but this can vary to a great degree. Some will even find the strong Kappa binding of oxycodone dysphoric to the point of discontinuation. If it can control the pain hydrocodone is generally more uniform in effect.. just wish the non-acetaminophen formulations were used more often due to hepatic toxicity.