what is it mechanism of action?
8 Sep 2009
Oxytocin is a polypeptide hormone of the posterior lobe of the pituitary gland.
Oxytocin exerts a selective stimulant and rhythmic contraction action on the smooth muscle of the uterus, especially near the end of pregnancy. It increases the frequency of existing contractions and raises the tone of the uterine musculature. Depending on dose, uterine motility may be increased moderately or increased to a sustained tetanic contraction. Oxytocin also has an antidiuretic effect which increases water reabsorption from the glomerular filtrate.
For more information on oxytocin see http://www.drugs.com/pro/oxytocin.html
- Oxytocin Information for Consumers
- Oxytocin Information for Healthcare Professionals (includes dosage details)
- Side Effects of Oxytocin (detailed)
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It has been added as a hazardous drugs by NIOSH - our hospital pharmacists want the L&D nurses to glove when admixing, spiking or handling IV ...