What if I have other medical problems , should I take this medication?

The only known interaction is between Lisinopril and Savella, which may cause a decrease in blood pressure. Otherwise it does not have any interactions with your other medicines. I would say it would be safe to take so long as your blood pressure is monitored.

Effects of interaction stated below:

Many psychotherapeutic and CNS-active agents (e.g., anxiolytics, sedatives, hypnotics, antidepressants, antipsychotics, opioids, alcohol, muscle relaxants) exhibit hypotensive effects, especially during initiation of therapy and dose escalation. Coadministration with antihypertensive agents, in particular vasodilators and alpha-blockers, may result in additive effects on blood pressure and orthostasis.

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MANAGEMENT: Caution is advised during coadministration of these agents. Close monitoring for development of hypotension is recommended. Patients should be advised to avoid rising abruptly from a sitting or recumbent position and to notify their physician if they experience dizziness, lightheadedness, syncope, orthostasis, or tachycardia.

http://www.drugs.com/interactions-check.php