What happenes when u take the isosorbide dinitrate with xanax 0.25mg?

Hello,

Interactions between your selected drugs

alprazolam ↔ isosorbide dinitrate
Applies to: Xanax (alprazolam), isosorbide dinitrate
MONITOR: Many psychotherapeutic and CNS-active agents (e.g., anxiolytics, sedatives, hypnotics, antidepressants, antipsychotics, opioids, alcohol, muscle relaxants) exhibit hypotensive effects, especially during initiation of therapy and dose escalation. Coadministration with antihypertensive agents, in particular vasodilators and alpha-blockers, may result in additive effects on blood pressure and orthostasis.

MANAGEMENT: Caution is advised during coadministration of these agents. Close monitoring for development of hypotension is recommended. Patients should be advised to avoid rising abruptly from a sitting or recumbent position and to notify their physician if they experience dizziness, lightheadedness, syncope, orthostasis, or tachycardia.

Other drugs that your selected drugs interact with

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isosorbide dinitrate interacts with more than 100 other drugs.
Xanax (alprazolam) interacts with more than 300 other drugs.

Interactions between your selected drugs and food

alprazolam ↔ food
Applies to: Xanax (alprazolam)
GENERALLY AVOID: The pharmacologic activity of oral midazolam, triazolam, and alprazolam may be increased if taken after drinking grapefruit juice. The proposed mechanism is CYP450 3A4 enzyme inhibition.

MANAGEMENT: The manufacturer recommends that grapefruit juice should not be taken with oral midazolam. Patients taking triazolam or alprazolam should be monitored for excessive sedation. Alternatively, the patient could consume orange juice which does not interact with these drugs.

http://www.drugs.com/interactions-check.php?drug_list=1400-0,133-54

Take care,