Answers (1)
14 Nov 2011
Zanaflex (tizanidine) shows up in your system as tizanidine and its metabolites (none of which are active). Tizanidine is extensively metabolized,
with the two major metabolites of tizanidine having been
identified as DS-200-717 (metabolite 3, guanidine, [(5-chloro-4-(2-
imidazolin-4-on-2-ylamino)-2,1,3-benzothiazdiazole] and DS-201-
341 (metabolite 4, amide, [5-chloro-4-(guanidino)-2,1,3-benzothiazdiazole]).
http://dmd.aspetjournals.org/content/27/2/201.full.pdf
Pharmacokinetics, Metabolism and Excretion
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