Skip to Content

What could be the the effects of melatonin (3mg) and zolpidem (5 mg) taken together?

Question is Closed
Report Favorite

Answers (1)


11 Apr 2010

You would definitely go to sleep but there would be no need to take the melatonin alongside the Ambien (zolpidem).I am prescribed 10mg Ambien for insomnia and have absolutely never needed to add anything to it to make it stronger or work better b/c it is so potent by itself. Melatonin is a mild and natural sleep-aid whereas Zolpidem is a strong narcotic one.If 5mg isnt giving you the help that you need then I strongly suggest you talk to your Dr about moving to 10mg tablets instead of adding or mixing different sleep-aids or ask him/her if you could take 2 tablets instead of just the one??

Votes: +1
christineATU 11 Apr 2010

Excellent advice mom! Hope your ailments are improving.

wwpeterson 11 Apr 2010

Thank you for your response mom of 7. 10mg of zolpidem was very effective for about 4 hrs. then I was awake. Seems 3mg melatonin and only half dosage of zolpidem gives me 6 to 7 hrs. Or at least if I wake up I can immediately go back to sleep for couple of hrs. I did not want to combine meds then find myself driving a car or doing laundry in my sleep as cautioned on the zolpidem packaging. My physical reaction to narcotic based drugs is not always as positive as with other people so I keep their usage to a minimum. Appreciate all the input and experiences of others.

Anonymous 11 Apr 2010

Had to giggle about the doing laundry or driving while on it.My husband HATES when I take Ambien b/c Ive been known to wander around aimlessly making elephant ears from scratch like you get from the fair or just doing kooky things like that.It causes short term amnesia so I tend to do things and not even remember them the next morning.But everyone else does and Im so embarrassed.Lol So are you saying you try to only take a small amt of it and add other sleep-aids with it so that you dont get the full crazy effect of it?

wwpeterson 12 Apr 2010

Yep! That's is just what I'm saying... not so much ambien, only 5mg., and I sleep longer with a little melatonin. I haven't seen any evidence of my doing anything crazy or "sleep walking" yet but did see this warning on the packaging. Also, I don't take ambien every night. Maybe only 4 times a week max. Trying to keep away from dependence. When I don't take ambien I take 4-5mg of melatonin with one extra strength tylenol.

Anonymous 12 Apr 2010

LOL you dont do anything crazy THAT YOU KNOW ABOUT!! LOL Im kidding. I dont take Ambien every day either.I take Trazadone which is prescription but it just makes my whole body so tired that I gladly go to bed.And I havent been known to do anything stupid wile taking it.Infact,I only take Ambien if Ive been up for a couple days and need instant sleep.I havent gotten addicted to either one but I give you kudos for making efforts not to get addicted.

Further Information

Search for questions

Still looking for answers? Try searching for what you seek or ask your own question.

Similar questions

Melatonin - is good for 11y boy?

i call hes doc. and she said the melatonin 3mg is good for him and my son is 11y old he dring the melatonin today i fell scar

3 answers 28 Sep 2009

25mg of melatonin..4hrs later still awake..can I take more??

The first time I took melatonin, I took 1mg the first night and fell asleep fairly quickly. The next night I had to take 3mg. Now, months later, ...

12 answers 10 Sep 2012

Can you take melatonin and oxycodone?

I take Melatonin, 3mg nightly. Have severe arm pain from rotator cuff injury.

1 answer 5 Mar 2013

Does melatonin stopped working after awhile?

I was taking melatonin for several months and it worked great. Then, it stopped working and I began having insomnia. Im also on Impramine, an ...

2 answers 2 May 2014