28 Mar 2010
Sulphasalazine (sulfazine) is coverted in the body to mesalamine (asacol) and it is this drug which exerts its therapeutic action.
This is from http://www.drugs.com/pro/asacol.html
"... Mesalamine is thought to be the major therapeutically active part of the sulfasalazine molecule in the treatment of ulcerative colitis. Sulfasalazine is converted to equimolar amounts of sulfapyridine and mesalamine by bacterial action in the colon. The usual oral dose of sulfasalazine for active ulcerative colitis is 3 to 4 grams daily in divided doses, which provides 1.2 to 1.6 grams of mesalamine to the colon."
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He asked the Dr. to lower the intake.Was told No.Please advice.
3 answers • 18 Dec 2009
1 answer • 5 Oct 2011
I have a colitis condition, Sulfazine does appear to help but I always seem to have my sleep interrupted. Is this common? Michael
3 answers • 2 Feb 2012
I have been on the above regimen for several years and have successfully avoided flareups of my ulcerative colitis. However, I am try to find the ...
0 answers • 7 May 2012
I am on asacol ec 400 have been on it for 1- 1/2 months and have had hair loss.I have type 2 diabetes.
1 answer • 21 Jun 2012