What are the cardiac consequences experienced with use of sutent?

8 Jul 2010

Hello,

SUTENT is indicated for the treatment of gastrointestinal stromal tumor after disease progression on or intolerance to imatinib mesylate.
Advanced Renal Cell Carcinoma

SUTENT is also indicated for the treatment of advanced renal cell carcinoma.

The most common adverse reactions ( ≥ 20%) in patients with GIST or MRCC are fatigue, asthenia, diarrhea, nausea, mucositis/stomatitis, vomiting, dyspepsia, abdominal pain, constipation, hypertension, rash, hand-foot syndrome, skin discoloration, altered taste, anorexia, and bleeding. The potentially serious adverse reactions of left ventricular dysfunction, QT interval prolongation, hemorrhage, hypertension, and adrenal function.

My best wishes from a caring individual.

8 Jul 2010

thanks for the input - each recommended treatment is unchartered waters and trying to learn about each helps combat the fear of the unknown.