My husband has heart problems but has appreciated some improvement in heart function - EF now up to 50-55%. He has taken 2 rounds of Afinitor and we are told his cancer is stable. Sutent has now been suggested to address advanced renal cell carcinoma. We are clearly concerned about cardiac consquences and I was curious what other patients have experienced as it relates to reduced heart function.
8 Jul 2010
SUTENT is indicated for the treatment of gastrointestinal stromal tumor after disease progression on or intolerance to imatinib mesylate.
Advanced Renal Cell Carcinoma
SUTENT is also indicated for the treatment of advanced renal cell carcinoma.
The most common adverse reactions ( ≥ 20%) in patients with GIST or MRCC are fatigue, asthenia, diarrhea, nausea, mucositis/stomatitis, vomiting, dyspepsia, abdominal pain, constipation, hypertension, rash, hand-foot syndrome, skin discoloration, altered taste, anorexia, and bleeding. The potentially serious adverse reactions of left ventricular dysfunction, QT interval prolongation, hemorrhage, hypertension, and adrenal function.
My best wishes from a caring individual.
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