I've been on 450 mg for several years. I have had alot of agitation and am short tempered. I don't know if its me or the medicine to be honest. Otherwise this medication really saved my life. Depression got me to the point I couldn't function and my life is just fine in that department due to Wellbutrin. Anyone else have anger issues / agitataion?
28 Jul 2010
Uh, yeah. lol. I thought that was just me having a moodswing. haha. I'm diagnosed with being bipolar II and for the most part I am pretty even with my moods, especially in the spring/summer months. I am on 450mg of Wellbutrin XL and 400mg of Topamax. I used to be on Lamical and Geodon a few years ago to help with mood stabilization, but I had ECT (electro-convulsive therapy) because my depression was so difficult to treat with meds and the Dr. was looking for a way to reduce or eliminate some or all of my meds. Well, it started out as me only being on 150mg of Wellbutrin XL and 50mg of Topamax and they took me off my other 2 meds..and over the past 2 1/2 years I have went all the way back up to my max dose of Topamax and Wellbutrin and I still get depressed pretty bad occasionally and when I get agitated my fiance' says I'm pretty mean about things..like not just a little crabby.
Recently I also had to get some Klonopin for anxiety (as needed) because that part of the bipolar disorder has been starting to act up again too. I know this may no be EXACTLY like what you have gone through, but I AM on 450 mg of Wellbutrin XL, and I AM suffering from a form of depression.
29 Jul 2010
Hi Venice Gal, Wellbutrin can cause aggitation and panic attacks!!
An excellent shrink once told me that Wellbutrin is the worst anti-D for anyone who has anxiety problems, and 'tis true... from personal experience.
Talk with your doc about the aggitation you feel, perhaps an anti-D that has a calming effect might be a better option.
Wishing you the best,
23 Nov 2010
YES! I've had MANY more angry outbursts and they have been more extreme and quick. Hard to stop once they start. Interesting comments about anxiety. Also applies here. While there are unpleasant side effects that Wellbutrin doesn't have, this anger and quick/short temper is quite problematic in family life.
18 Sep 2012
Oh wow! So glad I am not the only one.
I suffer from severe anxiety. One day I started shaking and it didn't stop for a year. I was on Paxil for a while but my libido went to zero so my doc switched me to Wellbutrin. Libido back to normal but I kept having these extreme anger outbursts. The smallest things will set me off and I seriously want to break stuff.
I guess I'll have to continue to walk away from those situations but I am glad to learn that it's from the drug.
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