more details: i am a female, age 49, took it for pain that ran from my hips down to my calfs, cause still unknown, occ. back pain, been an athlete all of my life so pain comes with the territory, had been on pristiq w/Tramadol for almost 2 years and did not know it was contraindicated,the depression is very bad now. been weaning off for a week. had been as high as 400 mg per day along with advil and tylenol at times...