how does this improve memory loss and overall mental balance
Vitamin B12 Deficiency - memory loss?
- Posted:
- 19 Nov 2009 by iamcurious
- Topics:
- vitamin b12, vitamins, vitamin b12 deficiency
Details:
Responses (1)
suzanne662 Dec 2009
The above statement is not quite true.
More large clinical trials of vitamin B12 supplementation are needed to assess whether vitamin B12 has an effect on memory loss (dementia) and cognitive function.
This from http://dietary-supplements.info.nih.gov/factsheets/vitaminb12.asp
"... Dementia and cognitive function
Researchers have long been interested in the potential connection between vitamin B12 deficiency and dementia [47,69]. A deficiency in vitamin B12 causes an accumulation of homocysteine in the blood [6] and might decrease levels of substances needed to metabolize neurotransmitters [70]. Observational studies show positive associations between elevated homocysteine levels and the incidence of both Alzheimer's disease and dementia [6,47,71]. Low vitamin B12 status has also been positively associated with cognitive decline [72].
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Shielding the Brain and Nerves
In animal and test-tube studies, Methylcobalamin has been shown to protect nerve cells against a wide variety of hostile environmental situations, including lack of vital cellular fuel, thiamine deficiency (which normally causes degeneration of the nervous system), oxygen starvation, and exposure to toxins like methylmercury, botulin, or nitroprusside, and the excitotoxic nerotransmitter glutamate. And the cyanocobalamin form of B12 in your multivitamin? When tested directly, it's usually been found that regular B12 supplements don't provide the neuroprotective and neuroregenerative benefits of Methylcobalamin.
Alzheimer's Disease
Expand this post...
Two trials have between them found that giving Methylcobalamin to people with Alzheimer's disease or related dementias (like Pick's disease) leads patients to have better interaction with other people and with the world around them, while improving mood and relieving neurological symptoms. The evaluation by the patients' familes and physicians was also improved. The findings in these trials on intellectual functioning were inconsistent: some scales showed improvements, but others did not. Both of these trials, however, used relatively low doses of Methylcobalamin.