Hi every one I have been taking tramadol for 3 years now and bu-trans patches 5-20 mg a day. I wear the patch for a week and then put a new one on. I also take dosulepin 75mg at night. The dose for the tramadol has been getting bigger all the time up to 600-700 mg a day. Does anyone know if taking this much could do any long term damage and when it is time to come off them what to expect. Thanks:)