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Vitamin E Deficiency Blog

Study Finds Vitamins E and C Don't Reduce Cataract Risk in Men

Posted 11 Nov 2010 by Drugs.com

THURSDAY, Nov. 11 – Long-term use of vitamin E and C supplements doesn't reduce the risk of age-related cataracts in men, a new study finds. "An estimated 20.5 million persons 40 and older in the United States show some evidence of age-related cataract," wrote study author William G. Christen, of Brigham and Women's Hospital and Harvard Medical School in Boston, and colleagues, in a news release. Because oxidative damage is a prominent feature of cataracts, he said, "one focus of nutrition research has been the link between dietary intake of nutrients with antioxidant potential, particularly vitamins E and C, and the risk of cataract." To study the effects of these vitamins, the researchers enrolled 11,545 healthy U.S. male physicians aged 50 and older. They were randomly assigned to take 400 international units (IU) of vitamin E daily or a placebo, or 500 milligrams of vitamin C on ... Read more

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Genetics May Play Role in Vitamin E Levels

Posted 20 Oct 2010 by Drugs.com

WEDNESDAY, Oct. 20 – Scientists have identified common genetic variations that may explain differences in peoples' ability to process vitamin E. Vitamin E is an antioxidant found in a number of oils, nuts and seeds as well as brightly-colored produce such as peppers, tomatoes and pumpkins. Previous research has found that vitamin E consumption has inconsistent effects on the amount of the vitamin in a person's body. It's been suspected that this is due to genetic variations. In this study, researchers led by Robert Parker of Cornell University in Ithaca, NY, looked at two versions of cytochrome P450 4F2 (CYP4F2), the enzyme that breaks down vitamin E. One variant, W12G, is more common in black Americans, and the V433M version is more common in Americans of European descent. Compared to the normal CYP4F2 enzyme, the W12G variant was better able to degrade several commonly occurring ... Read more

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