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Viagra May Help Children With Rare Blood Pressure Disorder

Posted 25 Oct 2011 by Drugs.com

TUESDAY, Oct. 25 – New research suggests that the active ingredient in the erectile dysfunction drug Viagra, which was initially developed as a treatment for heart disease, could help children with a rare condition called pulmonary arterial hypertension. The drug, which is expensive to take regularly and has side effects, is already approved to treat the condition in adults. And some pediatricians use it to treat children, said Dr. Thomas Kulik, senior associate in cardiology at Children's Hospital Boston. But it has not yet received U.S. Food and Drug Administration approval for that purpose. Pulmonary arterial hypertension, a rare condition, causes abnormally high blood pressure in the arteries that lead to the lungs. It can be inherited, accompany some forms of heart disease or occur for no known reason, Kulik said. The disease can limit the ability to exercise and lead to heart ... Read more

Related support groups: Viagra, Cialis, Pulmonary Hypertension, Sildenafil, Tadalafil, Revatio, Adcirca

Accidental Medication Poisonings in Kids on the Rise

Posted 16 Sep 2011 by Drugs.com

FRIDAY, Sept. 16 – Despite ongoing prevention efforts, a growing number of young children are being accidentally poisoned with medications, according to new research. The study, which was based on data reported to the American Association of Poison Control Centers between 2001 and 2008, found that medication poisoning among children aged 5 and under increased by 22 percent, although the number of children in the United States in this age group rose by only 8 percent during the study period. "The problem of pediatric poisoning in the U.S. is getting worse, not better," Dr. Randall Bond, of Cincinnati Children's Hospital Medical Center, said in a hospital news release. In conducting the study, which is scheduled for publication in the Journal of Pediatrics, the researchers reviewed information on over 544,000 children who landed in the emergency department due to medication poisoning ... Read more

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New Uses Found for Old Drugs

Posted 17 Aug 2011 by Drugs.com

WEDNESDAY, Aug. 17 – Many drugs already approved to combat certain illnesses may also be helpful in treating a slew of other seemingly unrelated health problems, a new study indicates. Researchers from the Stanford University School of Medicine used computers to pair drugs with all illnesses for which they might be beneficial. They argued their findings make the case for drug repositioning – or the use of existing drugs to boost progress on the development of new treatments – for other serious conditions. One high-profile example of how a drug can be used to treat conditions for which it was not originally intended involves Viagra. This medication was first developed to treat heart problems. It turned out that Viagra is also effective in treating erectile dysfunction as well as a lung disorder called pulmonary hypertension. The researchers from Stanford, however, sought to predict ... Read more

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Many Men Over 75 Still Sexually Active: Study

Posted 6 Dec 2010 by Drugs.com

MONDAY, Dec. 6 – Life for men aged 75 or older doesn't mean an end to sex, according to an Australian study. The researchers found that almost a third of these older men were sexually active at least once a year – including about 1 in 10 men aged 90 to 95. What's more, many older men who are sexually active say they'd love to be having more sex. Others are forgoing sex due to health issues, low testosterone levels or simply a lack of partners. The study, based on a survey of Australian men aged 75-95, most of whom were married or living with a partner, found that younger seniors were busiest of all: 40 percent of those aged 75-79 said they'd had sex in the past 12 months. But even among those aged 90-95, 11 percent reported sexual activity with someone else over the prior year. "Although many people, including some clinicians, continue to believe that sexual activity is not important ... Read more

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Pediatricians Want to Restrict Ads for Tobacco, Booze, Viagra

Posted 27 Sep 2010 by Drugs.com

MONDAY, Sept. 27 – The American Academy of Pediatrics doesn't want children exposed to tobacco ads at all, and wants to limit their exposure to alcohol marketing and advertisements for erectile dysfunction drugs and other prescription medications. Those are just a few of the recommendations in its new policy statement, "Children, Adolescents, Substance Abuse, and the Media," published in the October issue of Pediatrics. "Although parents, schools and the federal government are trying to get children and teenagers to 'just say no' to drugs, more than $25 billion worth of cigarette, alcohol and prescription drug advertising is effectively working to get them to 'just say yes' to smoking, drinking and other drugs," wrote the policy's authors. Every year, more than 400,000 people in the United States die from smoking-related illness, according to the policy statement. And, more than ... Read more

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Drugs Like Viagra Linked to Higher Rates of STDs

Posted 6 Jul 2010 by Drugs.com

MONDAY, July 5 – Middle-aged and older men who take erectile dysfunction drugs such as Viagra are more likely to have sexually transmitted diseases, a new study of more than 1.4 million men finds. Researchers at Massachusetts General Hospital and the University of Southern California say the fault lies not with the drugs but rather the high risk behaviors of the men who request them. And doctors should counsel these patients about safe sex practices, they said. Small studies of men who have sex with men have associated the use of ED drugs with higher risk behaviors and increased rates of STDs, but this report, published in the July 6 issue of the Annals of Internal Medicine, is said to be the first to examine the relationship between ED drugs and STD risk in a large, representative sample of privately insured older men. The researchers had no way of knowing how many of the men were ... Read more

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Viagra Linked to Hearing Loss

Posted 19 May 2010 by Drugs.com

WEDNESDAY, May 19 – The erectile dysfunction drug Viagra, and possibly other similar medications, may prompt long-term hearing loss among users, a new study suggests. In the May 18 issue of the Archives of Otolaryngology – Head and Neck Surgery, researchers from the University of Alabama at Birmingham discuss evidence supporting an association between the onset of hearing problems and Viagra. The medication is one of the so-called class of phosphodiesterase type 5 inhibitors (PDE-5i), which also includes Cialis and Levitra. The finding follows the 2007 decision by the U.S. Food and Drug Administration to adjust labeling for such medications to more prominently display warnings about hearing loss risks. The move stemmed from reports that year regarding sudden hearing loss among users of these drugs. "It appears from these findings that the current government warning regarding hearing ... Read more

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Viagra May Aid Those With Lung Fibrosis

Posted 18 May 2010 by Drugs.com

TUESDAY, May 18 – People with a serious lung disease that causes progressive scarring of the lung tissue might get some relief from sildenafil, the drug used in Viagra, a new study finds. The disease, called idiopathic pulmonary fibrosis, causes the lungs to become increasingly thick and stiff, reducing the ability to breathe. There's no known cause, and there's little in the way of treatment, researchers say. Most people with the disease live just three to five years after diagnosis. "There are about 150,000 patients in the United States and about 5 million worldwide with the disease," said lead researcher, Dr. David A. Zisman, from the Sansum Clinic in Santa Barbara, Calif. He cited Jerry Lewis, Evel Knievel and Robert Goulet as celebrities who had the disease, which he said has "no proven therapy, except lung transplantation, and survival is quite limited." His research team decided ... Read more

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Impotence Drugs May Aid Brain Tumor Treatment

Posted 12 May 2010 by Drugs.com

WEDNESDAY, May 12 – A drug already approved for the treatment of erectile dysfunction may actually help boost the effectiveness of treatments for brain tumors tied to both lung and breast cancer, research shows. The finding stems from an animal study that indicated that leading erectile dysfunction medications sildenafil (Viagra) and vardenafil (Levitra) can enable the chemotherapy drug Herceptin to more easily penetrate the so-called blood-brain barrier that must be breached in order to successfully target cancer that has spread to the brain. Although the blood-brain barrier is a naturally occurring mechanism designed to protect the brain from exposure to dangerous substances, in the case of cancer treatment it can significantly impede drug delivery, particularly of large-molecule drugs, such as Herceptin. However, erectile dysfunction drugs appear to increase the barrier's ... Read more

Related support groups: Viagra, Levitra, Brain Tumor, Sildenafil, Revatio, Vardenafil

Fake Drugs Bought on the Web Pose Big Health Risks

Posted 29 Jan 2010 by Drugs.com

FRIDAY, Jan. 29 – People who buy prescription medications over the Internet, especially drugs purporting to treat erectile dysfunction, are playing Russian roulette with their lives, a new study contends. At best the drugs won't help you and at worst they could kill you, the review article said. "You may be wasting your money or you may actually be hurting yourself," said Dr. Margaret E. Wierman, professor of medicine at the University of Colorado at Denver and chief of endocrinology at the Denver VA Medical Center, who was not involved with the study. Counterfeit Internet drugs are a mushrooming problem. Seizures of fake drugs in Europe quadrupled between 2005 and 2007. And the number of investigations undertaken by the U.S. Food and Drug Administration increased by a factor of eight between 2000 and 2006, according to the study, published in the International Journal of Clinical ... Read more

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Guidelines Urge Use of Erectile Dysfunction Drugs

Posted 2 Dec 2009 by Drugs.com

THURSDAY, Oct. 22 – Doctors should prescribe oral phosphodiesterase type 5 (PDE-5) inhibitor drugs, such as Viagra, Cialis and Levitra, for men with erectile dysfunction, unless the patient is on nitrate therapy, according to a clinical practice guideline issued by the American College of Physicians. The type of erectile dysfunction (ED) drug prescribed should be based on the individual preferences of patients, including cost of medication, ease of use and types of side effects, the authors noted. "The evidence is insufficient to compare the effectiveness or adverse effects of different PDE-5 inhibitors for the treatment of ED because there were only a few head-to-head trials," guideline lead author Dr. Amir Qaseem, senior medical associate with the ACP, said in a news release. Qaseem and colleagues analyzed the findings of 130 studies that evaluated PDE-5 inhibitors alone or combined. ... Read more

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Viagra Helpful for Children With Heart Defect

Posted 1 Dec 2009 by Drugs.com

TUESDAY, Nov. 17 – The erectile dysfunction drug sildenafil, commonly known as Viagra, boosts the heart's pumping ability in children and young adults who've had the Fontan operation to correct single-ventricle heart defects, researchers report. In the Fontan operation, doctors direct venous blood directly to the pulmonary arteries, bypassing the heart. The procedure is the third surgery in staged reconstruction for children with single-ventricle defects, explained the researchers from the Children's Hospital of Philadelphia in a news release from the American Heart Association. The study included 27 children and young adults who'd undergone the Fontan operation an average of 11 years earlier. The patients, average age 15, were given either a placebo or 20 milligrams of sildenafil three times daily for six weeks. That was followed by six weeks of no drug or placebo, and then the ... Read more

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FDA Medwatch Alert: Viagra (sildenafil)

Posted 18 Oct 2007 by Drugs.com

[Posted 10/18/2007] FDA informed healthcare professionals of reports of sudden decreases or loss of hearing following the use of PDE5 inhibitors Viagra, Levitra, Cialis for the treatment of erectile dysfunction, and Revatio for the treatment of pulmonary arterial hypertension. In some cases, the sudden hearing loss was accompanied by tinnitus and dizziness. Medical follow-up on these reports was often limited which makes it difficult to determine if the loss of hearing was related to the use of one of the drugs, an underlying medical condition or other risk factors for hearing loss, a combination of these factors or other factors. The PRECAUTIONS and ADVERSE REACTIONS sections of the approved product labeling for Viagra, Levitra, and Cialis were revised. FDA is working with the manufacturer to revise the labeling for Revatio.[October 18, 2007 - Viagra Information page - FDA] Read more

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FDA Medwatch Alert: Viagra (Sildenafil citrate)

Posted 8 Jul 2005 by Drugs.com

[Posted 07/08/2005] FDA notified healthcare professionals of updated labeling for Cialis, Levitra and Viagra to reflect a small number of post-marketing reports of sudden vision loss, attributed to NAION (non arteritic ischemic optic neuropathy), a condition where blood flow is blocked to the optic nerve. FDA advises patients to stop taking these medicines, and call a doctor or healthcare provider right away if they experience sudden or decreased vision loss in one or both eyes. Patients taking or considering taking these products should inform their health care professionals if they have ever had severe loss of vision, which might reflect a prior episode of NAION. Such patients are at an increased risk of developing NAION again. At this time, it is not possible to determine whether these oral medicines for erectile dysfunction were the cause of the loss of eyesight or whether the ... Read more

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Viagra Trial for Sickle Cell Lung Problems Halted

Posted 28 Jul 2009 by Drugs.com

TUESDAY, July 28 – The first clinical trial of a treatment for pulmonary hypertension in adults with sickle cell anemia has been stopped because of severe side effects in some participants. The trial involved sildenafil – marketed as Viagra when it is used to treat erectile dysfunction and Revatio when used for pulmonary arterial hypertension, or high blood pressure in the lungs. "This was a very big disappointment," said Dr. Mark Gladwin, lead investigator of the study, which was sponsored by the U.S. National Heart, Lung, and Blood Institute. "We were very excited about this drug. It has a very high safety profile and has worked in every form of pulmonary hypertension. The preliminary data showed a lowering in pulmonary hypertension in sickle cell patients." Pulmonary hypertension affects as many as 30 percent of people with sickle cell disease. "It's the highest risk of death, so ... Read more

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