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Could Adaptable Bacteria Cause Repeat Urinary Tract Infections?

Posted 17 days ago by Drugs.com

WEDNESDAY, May 8 – Women suffering from recurring urinary tract infections may carry a particularly hearty strain of E. coli bacteria that flourishes in both the gut and the bladder, and can migrate back and forth despite repeated treatments, a small new study finds. Doctors believe that urinary tract infections are often caused by E. coli migrating from the gut to the urinary tract, according to study background information. But they have assumed that when the bacteria moves to the bladder, it loses its ability to flourish in the gastrointestinal tract. Now the research published May 8 in the journal Science Translational Medicine suggests some strains of E. coli may be more adaptable than previously thought. While studying a group of women who suffered from repeated episodes of urinary tract infection, the multinational team of researchers discovered strains of E. coli that can live ... Read more

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How Long Should Men's Urinary Infections Be Treated?

Posted 5 Dec 2012 by Drugs.com

WEDNESDAY, Dec. 5 – Extending antibiotic treatment for urinary tract infections in men won't lower the odds that the infection will return, compared with a shorter period of treatment, a new study finds. The best length of outpatient antibiotic treatment for women with urinary tract infection is known, but the optimum length for treatment in men is unclear. Length of antibiotic treatment is important, because therapy that's too short can lead to recurrent infection, while treatment that's too long can increase costs, promote antibiotic resistance and increase the risk of Clostridium difficile infection, the researchers noted. C. difficile, which can cause diarrhea or serious inflammation of the colon, typically occurs after taking antibiotics. This U.S. Veteran Affairs study included more than 33,000 men with an average age of 68 who received outpatient treatment for urinary tract ... Read more

Related support groups: Urinary Tract Infection, Clostridial Infection

More Proof Cranberry Juice Thwarts Infection

Posted 9 Jul 2012 by Drugs.com

MONDAY, July 9 – Cranberry juice and cranberry supplements really do help prevent urinary tract infections, a new study confirms. As many as 50 percent of women will develop at least one urinary tract infection in their lifetime, and up to 30 percent will develop recurrent urinary tract infections (UTIs), according to the experts. So researchers have long debated what role – if any – cranberries and cranberry-containing products play in preventing or treating these painful infections. For this new report, researchers from Taiwan analyzed 13 studies that compared cranberry-containing products to inactive placebo among a total of 1,616 individuals in North America and Europe. Most of the trials lasted six months. The result? These longtime folk remedies provide protection against common urinary tract infections, especially among women, women with repeat infections, children, and those ... Read more

Related support groups: Urinary Tract Infection, Cranberry, Azo-Cranberry

Uncircumcised Boys at Higher Risk for Infection: Study

Posted 9 Jul 2012 by Drugs.com

MONDAY, July 9 – Uncircumcised boys are at higher risk for urinary tract infections, common bacterial infections that can scar the kidneys if untreated, according to a new study. The Canadian researchers also found the infection risk is greater regardless of whether or not the boys have a visible urethra. Circumcision involves removal of the foreskin at the tip of the penis. For the study, published July 9 in the journal CMAJ, the researchers analyzed information on nearly 400 boys who visited an emergency room with symptoms of a urinary tract infection. Forty of these boys had not been circumcised and had a visible urethra; 269 weren't circumcised and had a partially visible or nonvisible urethra; and 84 were circumcised. "We thought that incomplete foreskin retractability with a poorly visible urethral [opening] may be associated with increased risk of urinary tract infection," the ... Read more

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Study Ties Secondhand Smoke to Bladder Irritation in Kids

Posted 20 May 2012 by Drugs.com

SUNDAY, May 20 – Parents who smoke may put their children at greater risk for bladder irritation, according to a small new study. Young children between the ages of 4 and 10 were at particular risk from exposure to secondhand smoke. Bladder irritation involves the urge to urinate, urinating more frequently and incontinence. The study revealed that exposure to secondhand smoke is linked to more severe symptoms of bladder irritation: The more exposure the children had, the worse their symptoms became. Led by Dr. Kelly Johnson, researchers from Robert Wood Johnson University Hospital and Rutgers University analyzed survey information on 45 children ranging in age from 4 to 17. All had symptoms of bladder irritation. The researchers divided the children into four groups based on the severity of their symptoms: very mild, mild, moderate or severe. Twenty-four of the children studied had ... Read more

Related support groups: Urinary Tract Infection, Smoking

Germs Behind Urinary Tract Infections Becoming More Resistant to Drugs

Posted 4 May 2012 by Drugs.com

FRIDAY, May 4 – E. coli bacteria's resistance to ciprofloxacin (Cipro), the most widely prescribed antimicrobial for urinary tract infections in the United States, increased five-fold between 2000 and 2010, according to a new study. The surveillance study of more than 12 million bacteria also found that nearly one-fourth of E. coli in 2010 were resistant to trimethoprim-sulfamethoxazole (brand name Bactrim), the second most commonly prescribed drug for urinary tract infections. The study was published in the April issue of the journal Antimicrobial Agents and Chemotherapy. E. coli accounts for 75 percent to 95 percent of urinary tract infections, which are among the most common infections in humans. Half of all women experience at least one urinary tract infection in their lifetime. E. coli antimicrobial resistance reduces the likelihood of clinical cure, increases the risk of ... Read more

Related support groups: Urinary Tract Infection, Cipro, Ciprofloxacin, Cipro IV, Cipro Cystitis Pack, Cipro XR, Proquin XR

E. Coli in Chicken Linked to Urinary Tract Infections

Posted 15 Feb 2012 by Drugs.com

WEDNESDAY, Feb. 15 – Scientists have long believed that urinary tract infections are typically caused by a person's own E. coli bacteria, but a new Canadian study suggests the bacteria may more often than not come from chickens. Yes, chickens. As many as 85 percent of urinary tract infections are caused by E. coli, according to the report in the March issue of Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention. Researchers compared the genetic fingerprints of E. coli from these infections to that of E. coli from chicken, beef and pork. And they found a match: chicken. What's more, they report that the infections probably came directly from the chickens, not from human contamination during food processing. "Chicken may be a reservoir for the E. coli that cause infections like urinary tract infections," said study author Amee Manges, who is ... Read more

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Science Probes How Probiotic Yogurts Affect Your Gut

Posted 26 Oct 2011 by Drugs.com

WEDNESDAY, Oct. 26 – Researchers have put the health promises of popular probiotic yogurts to the test and found they may alter the way in which food is metabolized. But whether that means probiotic foods and supplements can improve your health remains to be seen, they said. "Federal regulatory agencies are increasingly interested in evaluating all the health claims being made by probiotic food manufacturers," said study co-author Dr. Jeffrey Gordon, a biologist and director of the Center for Genome Sciences at Washington University School of Medicine, in St. Louis. "So what we did was try to develop a model for the human gut that can give us a way to measure the effects." What they saw, Gordon said, "is that adding a few billion of these microbial organisms to a gut community already containing tens of trillions of bacteria can, in fact, influence the metabolism of food ingredients. ... Read more

Related support groups: Diarrhea, Urinary Tract Infection, Irritable Bowel Syndrome, Eczema, Bladder Cancer

Antibiotics Beat Cranberries at Fighting Urinary Tract Infections in Study

Posted 25 Jul 2011 by Drugs.com

MONDAY, July 25 – Many women swear by cranberry juice or capsules for the treatment and prevention of urinary tract infections, but new Dutch research indicates that antibiotics may be more effective even if they contribute to a greater risk for antibiotic resistance. "Cranberries are less effective in the prevention, but do not result in resistant microorganisms," said study author Dr. Suzanne Geerlings, an infectious diseases expert at the Academic Medical Center in Amsterdam. "Women with recurrent UTIs [urinary tract infections] do not like taking antibiotics for a long period because they know [about] the resistance problem. I think that doctors have to discuss the results of this study with the individual patients to make the best choice." About half of all women will experience a UTI at some point in their lives, and 30 percent of women will develop recurrent UTIs. Escherichia ... Read more

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New Treatment for Urinary Tract Infections Called Promising

Posted 16 Apr 2011 by Drugs.com

FRIDAY, April 15 – Many women suffer from chronic urinary tract infections, but now a new treatment using a probiotic may provide lasting relief for some, a preliminary trial indicates. Urinary tract infections frequently recur and affect 2 percent to 3 percent of all women. The depletion of vaginal Lactobacillus crispatus, a type of bacteria, is linked with these painful infections, suggesting that replenishing the bacteria may be helpful. "The problem with urinary tract infection we are facing is antibiotic resistance," said researcher Dr. Thomas M. Hooton, a professor of clinical medicine at the University of Miami Miller School of Medicine. "So there is as push to develop non-antibiotic methods to prevent and treat infections," he added. Women who have recurring urinary tract infection have alterations in their vaginal bacteria. "There tends to be a reduction in Lactobacillus ... Read more

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Breast-Feeding for 6 Months May Prevent Infant Infections

Posted 28 Sep 2010 by Drugs.com

TUESDAY, Sept. 28 – Children who derive all their nutrition from breast-milk during their first six months of life are less prone to a host of common infections, new Greek research says. And when infection strikes, the ensuing illness is typically less severe among children who are exclusively breast-fed (having ingested no substitute formula) in their first half year, the study authors stated. The research, led by Emmanouil Galanakis from the department of pediatrics at the University of Crete in Heraklion, Greece, is published in the Sept. 28 online edition of the Archives of Disease in Childhood. In 2004, Galanakis and his colleagues looked at the feeding patterns and infection rates among nearly 1,000 Greek infants from birth to 1 year of age. All the infants had received their routine vaccinations and all were deemed to have access to high-quality health care. The study authors ... Read more

Related support groups: Urinary Tract Infection, Otitis Media, Upper Respiratory Tract Infection, Oral Thrush, Conjunctivitis, Gastroenteritis

Progress Made Toward Vaccine for Urinary Infections

Posted 2 Feb 2010 by Drugs.com

FRIDAY, Sept. 18 – A vaccine to prevent urinary tract infections shows early promise in tests on mice, according to University of Michigan researchers. For two decades, researchers have been trying to develop a vaccine to prevent urinary tract infections, which afflict about 53 percent of women and 14 percent of men at least once in their lives, according to background information in a university news release. The researchers screened more than 5,000 bacterial proteins and identified three strong candidates to use in a vaccine to fight Escherichia coli, the cause of most uncomplicated urinary tract infections. The new vaccine, administered in the nose, alerts the immune system to iron receptors on the surface of bacteria that play a major role in the spread of urinary tract infection. When tested in mice, the vaccine prevented infection and produced key types of immunity. The study ... Read more

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Foodborne E. Coli Suspected in Urinary Tract Infections

Posted 17 Dec 2009 by Drugs.com

WEDNESDAY, Dec. 16 – E. coli bacteria in food – commonly linked to food poisoning and the stomach pain and diarrhea that result – might also be the cause of some urinary tract infections. Researchers have found the same strains of the bacteria in chicken from stores and restaurants and in women with the infections. There's no evidence that the germs were transmitted directly to the women through the food they ate, although that's possible. Still, the findings are the first to suggest a possible link between the food supply and urinary tract infections, said Amee R. Manges, an assistant professor at McGill University in Montreal and lead author of a report on the discovery. It is published in the January issue of Emerging Infectious Diseases. "This may be happening more frequently then we expected," Manges said. In addition, she said, the transmission through food could boost the ... Read more

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CDC Study Links 2 Antibiotics to Birth Defects

Posted 1 Dec 2009 by Drugs.com

MONDAY, Nov. 2 – Taking antibiotics during pregnancy does not raise the risk for most birth defects, though there are some exceptions, new research has found. Penicillin, which is the most commonly used antibiotic during pregnancy, as well as erythromycin, cephalosporins and quinolones, other widely prescribed antibiotics, were not associated with increased risk for about 30 different birth defects. However, the study found that two types of antibiotics were linked with a higher risk for several birth defects: nitrofurantoins and sulfonamides, sometimes called "sulfa drugs," which are prescribed for urinary tract and other infections. Women whose children had anencephaly, a fatal malformation of the skull and brain, were three times more likely to have taken sulfonamides, the study found. Sulfonamides were also tied to an increased risk for such heart defects as hypoplastic left heart ... Read more

Related support groups: Urinary Tract Infection, Bactrim, Bactrim DS, Nitrofurantoin, Macrobid, Septra, Macrodantin, Septra DS, Cotrimoxazole, Sulfamethoxazole/Trimethoprim, Sulfatrim, SMZ-TMP DS, Sulfatrim Pediatric, Cotrim DS, Bactrim Pediatric, Cotrim, Bactrim IV, Bethaprim, Co-trimoxazole, Uroplus DS

Finding May Lead to New Drugs for Urinary Infections

Posted 20 Feb 2009 by Drugs.com

FRIDAY, Feb. 20 – Potential targets for new drugs to fight the bacteria that cause many urinary tract infections have been identified by U.S. researchers. Two molecules called yersiniabactin and salmochelin enable E. coli to steal iron from their hosts, which makes it easier for the bacteria to survive and reproduce. Identifying the two molecules – called siderophores – could help lead to the development of antibiotics that target pathogenic E. coli strains without harming beneficial bacteria in the gut. The findings appear in the Feb. 20 issue of PLoS Pathogens. "When we treat an infection with antibiotics, it's like dropping a bomb – nearly everything gets wiped out, regardless of whether it's helpful or harmful. We'd like to find ways to target the bad bacteria and leave the good bacteria alone, and these siderophores are a great lead in that direction," study author Jeff ... Read more

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Bladder Infection, Kidney Infections, Pyelonephritis, Urinary Acidification, Urinary Alkalinization, Bacterial Infection

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