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Urinary Tract Infection Blog

Related terms: Acute Bacterial Cystitis, Catheter-Associated Urinary Tract Infection (UTI), Chronic Urinary Tract Infection (UTI), Cystitis, acute bacterial, Infection, Urinary Tract, UTI, Catheter-Associated Urinary Tract Infection, Chronic Urinary Tract Infection, Urinary Infection

Combination Antibiotic Zerbaxa Approved

Posted 9 hours ago by Drugs.com

MONDAY, Dec. 22, 2014 – The combination antibiotic Zerbaxa (ceftolozane/tazobactam) has been approved by the U.S. Food and Drug Administration to treat adults with complicated abdominal infections and complicated urinary tract infections. The approval for abdominal infections was approved in combination with another drug, metronidazole, the agency said in news release. The approval for urinary tract infection includes infection of the kidney. Zerbaxa is the fourth antibiotic to be FDA-approved in 2014, following approval of Dalvance (dalbavancin), Sivextro (tedizolid) and Orbactiv (oritavancin). The drug's label includes a warning about decreased effectiveness among people with kidney impairment, the FDA said. The most common side effects reported during clinical testing included nausea, diarrhea, headache and fever. Zerbaxa is marketed by Cubist Pharmaceuticals, based in Lexington, ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection

FDA Approves Zerbaxa (ceftolozane/tazobactam) for Complicated Intra-Abdominal/Urinary Tract Infections

Posted 3 days ago by Drugs.com

December 19, 2014 – The U.S. Food and Drug Administration today approved Zerbaxa (ceftolozane/tazobactam), a new antibacterial drug product, to treat adults with complicated intra-abdominal infections (cIAI) and complicated urinary tract infections (cUTI). Zerbaxa is a combination product containing ceftolozane, a cephalosporin antibacterial drug, and tazobactam, a beta-lactamase inhibitor. Zerbaxa is used to treat cUTI, including kidney infection (pyelonephritis). It is used in combination with metronidazole to treat cIAI. Zerbaxa is the fourth new antibacterial drug approved by the FDA this year. The agency approved Dalvance (dalbavancin) in May, Sivextro (tedizolid) in June and Orbactiv (oritavancin) in August. “The FDA approval of several new antibacterial drugs this year demonstrates the agency’s commitment to increasing the availability of treatment options for patients and phy ... Read more

Related support groups: Urinary Tract Infection, Intraabdominal Infection

Childhood Urinary Tract Infection May Bring Lasting Harm to Kidneys

Posted 6 Aug 2014 by Drugs.com

TUESDAY, Aug. 5, 2014 – Urinary tract infections are the most common serious bacterial infections in young children, and almost one of every eight kids who gets one will end up with scarring on the kidneys and an increased risk of kidney failure later in life. Identifying those kids early is critical, and researchers now report that a combination of three factors – high fever, detection of kidney abnormalities via ultrasound and identification of the type of bacteria involved – spots such patients as accurately as a very unpleasant catheter-based test does. "We found that you more or less can predict the children who are at higher risk by looking at three different things when they come in," said study author Dr. Nader Shaikh, an assistant professor at the University of Pittsburgh and a pediatrician at the Children's Hospital of Pittsburgh. In the past, doctors used a combination ... Read more

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'Sterile' Urine May Be a Myth

Posted 19 May 2014 by Drugs.com

MONDAY, May 19, 2014 – Many people have heard that human urine is devoid of germs, but a new study seems to question that idea. "Doctors have been trained to believe that urine is germ-free," Dr. Linda Brubaker, dean of Loyola University Chicago Stritch School of Medicine, said in a university news release. "These findings challenge this notion." Brubaker's team analyzed urine samples from 90 women. It found bacteria both in the urine of healthy women as well as the urine of women with overactive bladder. However, the germs were different between the two groups, the researchers said. "The presence of certain bacteria in women with overactive bladder may contribute to overactive bladder symptoms," lead investigator Evann Hilt, a second-year master's student, theorized in the news release. But only more study can confirm whether those bacterial differences are "clinically relevant for ... Read more

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Urine Tests Don't Always Confirm Urinary Infections, Study Finds

Posted 13 Nov 2013 by Drugs.com

WEDNESDAY, Nov. 13 – When doctors suspect a patient has a urinary tract infection, they often request a urine sample so they can test for the presence of bacteria. Now, new research suggests this step may be unnecessary. Nearly one-quarter of women who had signs of a urinary tract infection – a burning feeling when urinating or feeling an urgent need to pee – had no evidence of bacteria in their urine or in their bladders, the study found. And although a number of urine culture tests found a variety of different bacteria, only one bug – Escherichia coli – was found in both the urine test and the bladder. These findings suggest that today's lab tests may not be refined enough to detect very small quantities of bacteria in the bladder. It's also possible that the symptoms may not be caused by a bladder infection, but instead may be caused by an infection in the urethra, the tube that ... Read more

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Urinary Tract Infection Often Puts Older Men in Hospital

Posted 18 Oct 2013 by Drugs.com

FRIDAY, Oct. 18 – Although urinary tract infections (UTIs) are much more common among women, older men who develop the condition are more likely to be hospitalized as a result, researchers have found. In addition, the urologists from Henry Ford Hospital pointed out that health care costs are 10 times higher when patients with UTIs need to be admitted to the hospital for treatment. They concluded that being able to predict which patients are most likely to be hospitalized could reduce these medical expenses. "We found that those patients who were hospitalized for treatment of urinary tract infections were most often older men, as well as those with serious kidney infections. They were also more likely to be seen at urban teaching hospitals, and/or treated in ZIP codes with higher median incomes," the study's lead author, Dr. Jesse Sammon, a researcher at Henry Ford's Vattikuti Urology ... Read more

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How Estrogen May Help Prevent Urinary Tract Infections After Menopause

Posted 20 Jun 2013 by Drugs.com

THURSDAY, June 20 – Estrogen treatment delivered vaginally may help prevent repeat urinary tract infections in postmenopausal women, new laboratory research suggests. Urinary tract infections are common among women, with one-quarter experiencing recurring infections. And age-related changes increase the likelihood of these infections developing after menopause, when estrogen production plummets. Until now, taking antibiotics prophylactically – to ward off recurrent urinary tract infections – has been the gold standard for these women, said Thomas Hannan, a research instructor in pathology and immunology at Washington University School of Medicine in St. Louis. "But antibiotic resistance is increasing, and some women are resistant to everything we have," Hannan said. "We need other options. We need non-antibiotic options." This study, published in the June 19 issue of the journal ... Read more

Related support groups: Urinary Tract Infection, Postmenopausal Symptoms, Vagifem, Estrace Vaginal Cream, Estring, Premarin Vaginal, Ogen Vaginal Cream, Dienestrol, Ortho Dienestrol

Can You Skip Antibiotics for Urinary Tract Infection?

Posted 4 Jun 2013 by Drugs.com

TUESDAY, June 4 – Some women with symptoms of a urinary tract infection may be able to skip the antibiotics typically prescribed and have their symptoms improve or clear, according to a new Dutch study. "In healthy people, many mild infections can be cured spontaneously," said study leader Dr. Bart Knottnerus, a researcher at the Academic Medical Center of the University of Amsterdam. A U.S. expert, however, had a number of cautions about the findings, including the small number of women studied. For the research, published May 31 in the journal BMC Family Practice, Knottnerus recruited women from 20 general medical practices in and around the Netherlands from 2006 to 2008. Women who had contacted their doctor complaining of frequent urination, painful urination or both were asked if they would be willing to delay antibiotics – but only if their symptoms had been present for no longer ... Read more

Related support groups: Urinary Tract Infection, Bladder Infection, Kidney Infections, Prevention of Bladder infection, Cystitis Prophylaxis, Pyelonephritis

Could Adaptable Bacteria Cause Repeat Urinary Tract Infections?

Posted 8 May 2013 by Drugs.com

WEDNESDAY, May 8 – Women suffering from recurring urinary tract infections may carry a particularly hearty strain of E. coli bacteria that flourishes in both the gut and the bladder, and can migrate back and forth despite repeated treatments, a small new study finds. Doctors believe that urinary tract infections are often caused by E. coli migrating from the gut to the urinary tract, according to study background information. But they have assumed that when the bacteria moves to the bladder, it loses its ability to flourish in the gastrointestinal tract. Now the research published May 8 in the journal Science Translational Medicine suggests some strains of E. coli may be more adaptable than previously thought. While studying a group of women who suffered from repeated episodes of urinary tract infection, the multinational team of researchers discovered strains of E. coli that can live ... Read more

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How Long Should Men's Urinary Infections Be Treated?

Posted 5 Dec 2012 by Drugs.com

WEDNESDAY, Dec. 5 – Extending antibiotic treatment for urinary tract infections in men won't lower the odds that the infection will return, compared with a shorter period of treatment, a new study finds. The best length of outpatient antibiotic treatment for women with urinary tract infection is known, but the optimum length for treatment in men is unclear. Length of antibiotic treatment is important, because therapy that's too short can lead to recurrent infection, while treatment that's too long can increase costs, promote antibiotic resistance and increase the risk of Clostridium difficile infection, the researchers noted. C. difficile, which can cause diarrhea or serious inflammation of the colon, typically occurs after taking antibiotics. This U.S. Veteran Affairs study included more than 33,000 men with an average age of 68 who received outpatient treatment for urinary tract ... Read more

Related support groups: Urinary Tract Infection, Clostridial Infection

More Proof Cranberry Juice Thwarts Infection

Posted 9 Jul 2012 by Drugs.com

MONDAY, July 9 – Cranberry juice and cranberry supplements really do help prevent urinary tract infections, a new study confirms. As many as 50 percent of women will develop at least one urinary tract infection in their lifetime, and up to 30 percent will develop recurrent urinary tract infections (UTIs), according to the experts. So researchers have long debated what role – if any – cranberries and cranberry-containing products play in preventing or treating these painful infections. For this new report, researchers from Taiwan analyzed 13 studies that compared cranberry-containing products to inactive placebo among a total of 1,616 individuals in North America and Europe. Most of the trials lasted six months. The result? These longtime folk remedies provide protection against common urinary tract infections, especially among women, women with repeat infections, children, and those ... Read more

Related support groups: Urinary Tract Infection, Cranberry, Azo-Cranberry

Uncircumcised Boys at Higher Risk for Infection: Study

Posted 9 Jul 2012 by Drugs.com

MONDAY, July 9 – Uncircumcised boys are at higher risk for urinary tract infections, common bacterial infections that can scar the kidneys if untreated, according to a new study. The Canadian researchers also found the infection risk is greater regardless of whether or not the boys have a visible urethra. Circumcision involves removal of the foreskin at the tip of the penis. For the study, published July 9 in the journal CMAJ, the researchers analyzed information on nearly 400 boys who visited an emergency room with symptoms of a urinary tract infection. Forty of these boys had not been circumcised and had a visible urethra; 269 weren't circumcised and had a partially visible or nonvisible urethra; and 84 were circumcised. "We thought that incomplete foreskin retractability with a poorly visible urethral [opening] may be associated with increased risk of urinary tract infection," the ... Read more

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Study Ties Secondhand Smoke to Bladder Irritation in Kids

Posted 20 May 2012 by Drugs.com

SUNDAY, May 20 – Parents who smoke may put their children at greater risk for bladder irritation, according to a small new study. Young children between the ages of 4 and 10 were at particular risk from exposure to secondhand smoke. Bladder irritation involves the urge to urinate, urinating more frequently and incontinence. The study revealed that exposure to secondhand smoke is linked to more severe symptoms of bladder irritation: The more exposure the children had, the worse their symptoms became. Led by Dr. Kelly Johnson, researchers from Robert Wood Johnson University Hospital and Rutgers University analyzed survey information on 45 children ranging in age from 4 to 17. All had symptoms of bladder irritation. The researchers divided the children into four groups based on the severity of their symptoms: very mild, mild, moderate or severe. Twenty-four of the children studied had ... Read more

Related support groups: Urinary Tract Infection, Smoking

Germs Behind Urinary Tract Infections Becoming More Resistant to Drugs

Posted 4 May 2012 by Drugs.com

FRIDAY, May 4 – E. coli bacteria's resistance to ciprofloxacin (Cipro), the most widely prescribed antimicrobial for urinary tract infections in the United States, increased five-fold between 2000 and 2010, according to a new study. The surveillance study of more than 12 million bacteria also found that nearly one-fourth of E. coli in 2010 were resistant to trimethoprim-sulfamethoxazole (brand name Bactrim), the second most commonly prescribed drug for urinary tract infections. The study was published in the April issue of the journal Antimicrobial Agents and Chemotherapy. E. coli accounts for 75 percent to 95 percent of urinary tract infections, which are among the most common infections in humans. Half of all women experience at least one urinary tract infection in their lifetime. E. coli antimicrobial resistance reduces the likelihood of clinical cure, increases the risk of ... Read more

Related support groups: Urinary Tract Infection, Cipro, Ciprofloxacin, Cipro IV, Cipro XR, Proquin XR, Cipro Cystitis Pack

E. Coli in Chicken Linked to Urinary Tract Infections

Posted 15 Feb 2012 by Drugs.com

WEDNESDAY, Feb. 15 – Scientists have long believed that urinary tract infections are typically caused by a person's own E. coli bacteria, but a new Canadian study suggests the bacteria may more often than not come from chickens. Yes, chickens. As many as 85 percent of urinary tract infections are caused by E. coli, according to the report in the March issue of Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention. Researchers compared the genetic fingerprints of E. coli from these infections to that of E. coli from chicken, beef and pork. And they found a match: chicken. What's more, they report that the infections probably came directly from the chickens, not from human contamination during food processing. "Chicken may be a reservoir for the E. coli that cause infections like urinary tract infections," said study author Amee Manges, who is ... Read more

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Bladder Infection, Kidney Infections, Pyelonephritis, Urinary Acidification, Urinary Alkalinization, Bacterial Infection

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