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CDC Issues New TB Treatment Guidelines
Posted 8 Dec 2011 by Drugs.com
THURSDAY, Dec. 8 – New guidelines on treating so-called "latent" tuberculosis infection in the United States should significantly shorten and simplify the course of the therapy from about 9 months to 3 months, according to the U.S. Centers for Disease Control and Prevention. The new guidelines for public health officials and health care providers – which are based on expert opinion and the results of three clinical trials – are a "game changer" for the treatment of TB in the United States, according to CDC Director Dr. Thomas Frieden. Latent TB infection occurs when a person is infected with TB bacteria but does not yet have symptoms and so cannot transmit the bacteria to others. However, if the bacteria becomes active, the person will develop the disease and can also spread it to others. Certain people, including those with weakened immune systems, are more likely to progress from ... Read more
Related support groups: Isoniazid, Tuberculosis, Tuberculosis -- Latent, Priftin, Rifapentine, Nydrazid
New TB Vaccine Passes Safety Trial
Posted 8 Apr 2009 by Drugs.com
WEDNESDAY, April 8 – An experimental tuberculosis vaccine called MVA85A proved safe in a small phase I clinical trial. The study included 12 people with latent tuberculosis infection, which, when re-activated, can cause full-blown TB. It's believed that about a third of the world's population has this latent infection. The participants, who had no other complicating factors, such as hepatitis or HIV, were given the vaccine and then followed for a year. The researchers concluded that the vaccine was safe, did not produce any immunopathology and was immunogenic in the patients. Some participants had side effects that included fever, headache, fatigue and mild concerns at the site of the vaccination. The findings appear in the April 15 issue of the American Journal of Respiratory and Critical Care Medicine. This study could be an important step forward in efforts to introduce a new ... Read more
Related support groups: Tuberculosis -- Prophylaxis, Tuberculosis -- Latent
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