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18th Century Mummies Reveal How TB Spread Through Europe

Posted 17 days ago by Drugs.com

WEDNESDAY, April 8, 2015 – Naturally mummified bodies from an 18th century crypt in Hungary provide new insight into tuberculosis infections in Europe during that time, researchers say. The discovery could also help health officials fight future tuberculosis (TB) outbreaks, the scientists suggested. Analyses of samples taken from the bodies in the crypt in the Dominican church of Vac uncovered 14 TB genomes. The research suggests that some of the victims had several strains of TB, perhaps a common occurrence when the disease was at its peak in Europe, the researchers said. "Microbiological analyses of samples from contemporary TB patients usually report a single strain of tuberculosis per patient. By contrast, five of the eight bodies in our study yielded more than one type of tuberculosis – remarkably from one individual we obtained evidence of three distinct strains," study author ... Read more

Related support groups: Tuberculosis, Tuberculosis - Latent, Tuberculosis - Active

Decline in U.S. Tuberculosis Rates Slows: CDC

Posted 19 Mar 2015 by Drugs.com

THURSDAY, March 19, 2015 – As health officials in Kansas struggle with an outbreak of tuberculosis at a local high school, federal officials reported Thursday that the annual decline in U.S. cases is slowing. In 2014, there were slightly more than 9,400 TB cases in the United States, a rate of three cases per 100,000 people. That's about 2 percent lower than the TB rate in 2013, according to data from the U.S. Centers for Disease Control and Prevention. However, "This decline in the rate of TB was the smallest decrease in more than a decade and suggests the need for ongoing evaluation of TB elimination strategies overall and within high-risk populations," the CDC researchers wrote. According to the CDC, tuberculosis is more common in certain groups, particularly foreign-born people, who have a TB rate 13 times higher than those born in the United States. Compared to whites, the TB rate ... Read more

Related support groups: Tuberculosis, Tuberculosis - Active

Sanofi Receives FDA Approval of Priftin (rifapentine) for Latent Tuberculosis Infection

Posted 2 Dec 2014 by Drugs.com

Bridgewater, NJ – December 2, 2014 / PR Newswire / — Sanofi announced today that following a priority review, the U.S. Food and Drug Administration has approved Priftin (rifapentine) in combination with isoniazid (INH) for a new indication for the treatment of latent tuberculosis infection (LTBI) in patients two years of age and older at high risk of progression to tuberculosis (TB) disease. Priftin is an antimycobacterial that has been approved since 1998, in combination with one or more antituberculosis drugs, for the treatment of active pulmonary TB caused by Mycobacterium tuberculosis. A person with LTBI is infected with the bacteria that cause TB, but does not feel sick, have symptoms, and cannot spread the bacteria to others. More than 11 million people living in the United States have LTBI, and about five to 10 percent of those – up to more than 1 million people – will develop TB ... Read more

Related support groups: Tuberculosis - Latent, Tuberculosis - Active, Rifapentine, Priftin

Smokers Twice As Likely to Get TB

Posted 12 Jan 2010 by Drugs.com

MONDAY, Aug. 24 – Smokers are twice as likely as nonsmokers to develop active tuberculosis (TB), a new study shows. Researchers analyzed data from nearly 17,000 people who took part in Taiwan's 2001 National Health Interview Survey. They found that current smokers had a 2.73 times higher risk of active TB than nonsmokers, while the risk for people who had smoked at some point in their lives was 2.69 times greater. After adjusting for other potential factors, the researchers determined that current smokers were two times more likely to develop active TB than nonsmokers. They also found that younger smokers were more likely than smokers over age 65 to develop active TB, compared to nonsmokers. The study appears in the Sept. 1 issue of the American Journal of Respiratory and Critical Care Medicine. "The small number of TB cases in this study prevented us from examining the age-gradient of ... Read more

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