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Medicines Are Biggest Culprit in Fatal Allergic Reactions: Study

Posted 10 Oct 2014 by Drugs.com

THURSDAY, Oct. 9, 2014 – Although food allergies have garnered a lot of attention lately, a new study reports that medications are actually the biggest cause of sudden deaths related to allergy. Over a little more than a decade, nearly 60 percent of the allergy-related deaths were caused by medications, while less than 7 percent were caused by food allergies, the study found. "Medications can be dangerous," said study researcher Dr. Elina Jerschow, director of the Drug Allergy Center at Montefiore Medical Center and assistant professor of medicine at Albert Einstein College of Medicine, in New York City. While research from other countries has reported medications as a major culprit in anaphylaxis-related deaths, Jerschow said, the problem has been less defined in the United States. One reason is that there is no national registry for anaphylaxis deaths, she said. The study was ... Read more

Related support groups: Provera, Amoxicillin, Doxycycline, Depo-Provera, Methotrexate, Penicillin, Bactrim, Cephalexin, Clindamycin, Metronidazole, Azithromycin, Lupron, Cipro, Accutane, Ciprofloxacin, Levaquin, Augmentin, Flagyl, Zithromax, Keflex

Cancer Chemotherapy Tied to Slight Rise in Risk for Leukemia

Posted 14 Feb 2013 by Drugs.com

THURSDAY, Feb. 14 – Chemotherapy can be a lifesaver for thousands of cancer patients, but a new study suggests that it might slightly raise the odds for a type of leukemia later in life. Over the past 30 years, the risk for acute myeloid leukemia (AML) has increased for patients who underwent chemotherapy for certain forms of cancer, particularly non-Hodgkin lymphoma, the new study found. On the other hand, the researchers from the U.S. National Cancer Institute said other cancer survivors may have a reduced risk for AML due to a change in chemotherapy agents that occurred decades ago. One expert not connected to the study stressed that cancer patients need to put the findings into perspective. "It's important to realize that the risk of developing acute myeloid leukemia related to prior chemotherapy is small and increases with the number of chemotherapy treatments given over time," ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Lupron, Accutane, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Gleevec, Fluorouracil, Rituxan, Zoladex, Tretinoin, Claravis, Votrient, Tarceva, Avastin

Cancer Patients Should Ask Doctors to Use Simple Terms

Posted 28 Sep 2011 by Drugs.com

WEDNESDAY, Sept. 28 – Cancer patients are often faced with many difficult-to-understand treatment choices that can have serious side effects and even mean the difference between life and death. That's why it's crucial that patients insist doctors use plain language in explaining the options, advised Angela Fagerlin, an associate professor of internal medicine at the University of Michigan Medical School and a researcher at the U-M Comprehensive Cancer Center. "People are making life and death decisions that may affect their survival and they need to know what they're getting themselves into. Cancer treatments and tests can be serious. Patients need to know what kind of side effects they might experience as a result of the treatment they undergo," Fagerlin said in a university news release. She and her colleagues outlined a number of tips to help patients get the information they need ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Lupron, Accutane, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Arimidex, Lupron Depot, Femara, Gleevec, Renal Cell Carcinoma, Lung Cancer, Fluorouracil, Rituxan, Zoladex, Tretinoin

Novartis International AG (CH) - FDA approves Tasigna for newly diagnosed chronic myeloid leukemia patients, data demonstrate major advance over Glivec

Posted 21 Jun 2010 by Drugs.com

Basel, June 17, 2010 - Following a priority review, the US Food and Drug Administration (FDA) has approved Tasigna (nilotinib) for the treatment of adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase. With this approval, Tasigna becomes the first new therapeutic option for newly diagnosed patients since the introduction of Glivec (imatinib)*, providing a major advance for patients with this blood cancer. The US approval was based on results of the ENESTnd (Evaluating Nilotinib Efficacy and Safety in Clinical Trials of Newly Diagnosed Ph+ CML Patients) Phase III clinical trial, which were published today in The New England Journal of Medicine (NEJM). "With the faster and deeper responses we are seeing with Tasigna, newly diagnosed CML patients will have a new and more effective treatment option," said Hervé Hoppenot, ... Read more

Related support groups: Chronic Myelogenous Leukemia (CML), Tasigna

Tasigna Approval Widened to Include Early Stages of Rare Leukemia

Posted 19 Jun 2010 by Drugs.com

FRIDAY, June 18 – The anti-cancer drug Tasigna (nilotinib) has received new approval from the U.S. Food and Drug Administration to include people in the early stages of a rare blood cancer called Philadelphia chromosome positive chronic phase chronic myeloid leukemia (Ph+CP-CML), the agency said in a news release. The disease, linked to a genetic abnormality, progresses slowly and affects the blood and bone marrow. Tasigna is thought to block a signal that causes leukemic cells to develop. The drug was approved in October 2007 for people in the disease's later stages. Users of Tasigna, however, are at greater risk of an abnormal heart rhythm disorder called QT prolongation. The FDA said earlier this year it sanctioned an updated medication guide and other strategies to inform patients and doctors of the drug's risks. The most common side effects reported during clinical testing ... Read more

Related support groups: Tasigna

Newer Drugs Beat Gleevec in Head-to-Head Trials

Posted 7 Jun 2010 by Drugs.com

SATURDAY, June 5 – Two new drugs, dasatinib (Sprycel) and nilotinib (Tasigna), appear better than imatinib (Gleevec) in treating patients with newly diagnosed chronic myeloid leukemia and should be considered as first-line treatments, two new studies show. The findings, which should change clinical practice, are to be presented Saturday at the American Society of Clinical Oncology annual meeting in Chicago and were simultaneously published online June 5 in the New England Journal of Medicine. "Both next-generation inhibitors of BCR-ABL [dasatinib and nilotinib] are superior to Gleevec in treating chronic myeloid leukemia when compared head-to-head after one year of follow-up," said Dr. Charles L. Sawyers, chair of the Human Oncology and Pathogenesis Program at the Howard Hughes Medical Institute at Memorial Sloan-Kettering Cancer Center in New York City and author of an accompanying ... Read more

Related support groups: Chronic Myelogenous Leukemia (CML), Gleevec, Tasigna, Sprycel, Dasatinib, Nilotinib, Imatinib

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Chronic Myelogenous Leukemia (CML)

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