Spiriva HandiHaler Blog
Join the 'Spiriva HandiHaler' group to help and get support from people like you.
FDA Medwatch Alert: Tiotropium (marketed as Spiriva HandiHaler)
Posted 3+ months ago by Drugs.com
[UPDATE 10/07/2008] FDA informed healthcare professionals that FDA has reviewed preliminary data from UPLIFT (Understanding the Potential Long-Term Impacts on Function with Tiotropium), a large, 4-year, placebo controlled clinical trial with Spiriva HandiHaler in approximately 6000 patients with chronic obstructive pulmonary disease. The preliminary results reported by Boehringer Ingelheim to the FDA showed that there was no increased risk of stroke with tiotropium bromide compared to placebo.
Two recent publications reported increased risk for mortality and/or cardiovascular events in patients who received tiotropium or inhaled anticholinergics. Both studies examined cardiovascular outcomes.
FDA expects to receive the complete report for UPLIFT in November Read more...
Related support groups: Spiriva, Spiriva HandiHaler
Spiriva Safe, Effective for COPD Patients
Posted 3+ months ago by Drugs.com
SUNDAY, Oct. 5 – For patients suffering from chronic obstructive pulmonary disease (COPD), tiotropium (Spiriva) improves lung function and quality of life but does not significantly slow progression of the disease, a new study finds.
Spiriva and a similar drug, Atrovent, are the most commonly prescribed once-daily treatments for COPD, a respiratory illness that's the fourth largest killer in the United States. Recently, studies have associated these medications with a 58 percent increased risk of heart attack, stroke and other cardiovascular problems. Read more...
Related support groups: Spiriva, Spiriva HandiHaler
Leading COPD Drugs Tied to Stroke, Heart Attack
Posted 3+ months ago by Drugs.com
TUESDAY, Sept. 23 – Common drugs prescribed for chronic obstructive pulmonary disease (COPD) are associated with an increased risk of heart attack, stroke and other cardiovascular problems, researchers report.
These inhaled anticholinergic agents, such as Spiriva and Atrovent, are the most commonly prescribed once-daily treatment for COPD, a respiratory illness that's the fourth largest killer in the United States. Read more...
Related support groups: Atrovent, Atrovent HFA, Spiriva, Spiriva HandiHaler, Chronic Obstructive Pulmonary Disease
FDA Medwatch Alert: Tiotropium (marketed as Spiriva HandiHaler)
Posted 3+ months ago by Drugs.com
[Posted 03/18/2008] Boehringer Ingelheim and FDA notified healthcare professionals that ongoing safety monitoring has identified a possible increased risk of stroke in patients who take Spiriva. This product contains tiotropium bromide and is used to treat bronchospasm associated with chronic obstructive pulmonary disease. Boehringer Ingelheim reported to the FDA that it has conducted an analysis of the safety data from 29 placebo controlled clinical studies (“pooled analysis”). Based on data from these studies, the preliminary estimates of the risk of stroke are 8 patients per 1000 patients treated for one year with Spiriva, and 6 patients per 1000 patients treated for one year with placebo. This means that the estimated excess risk of any type of stroke due to Spiriva i Read more...
Related support groups: Spiriva, Spiriva HandiHaler
FDA Medwatch Alert: Spiriva (tiotropium bromide inhalation powder) and Foradil (formoterol fumarate inhalation powder) Capsules
Posted 3+ months ago by Drugs.com
[Posted 02/29/2008] FDA informed healthcare professionals and consumers of the correct way to use Spiriva and Foradil inhalation powder capsules. FDA and the American Association of Poison Control Center’s (AAPCC) National Poison Data System have received many reports of patients swallowing Spiriva and Foradil capsules rather than placing the capsules in the inhalation devices. Both products are to be used in the HandiHaler (Spiriva) and Aerolizer (Foradil) devices to deliver the medicine to the lungs to improve breathing in patients with asthma, and in individuals affected by chronic obstructive lung disease and bronchitis. Both products will not treat a patient's breathing condition if the contents of a capsule are swallowed rather than inhaled. Healthcare professionals should disc Read more...
Related support groups: Foradil Aerolizer, Spiriva, Spiriva HandiHaler
Ask a Question
You may also be interested in...
Related Condition Support Groups
Chronic Obstructive Pulmonary Disease, Maintenance
