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Certain Cancer Drugs May Have Fatal Side Effects: Analysis
Posted 6 Feb 2012 by Drugs.com
MONDAY, Feb. 6 – Treatment with three relatively new cancer drugs may be linked to a slightly increased risk of death, a new analysis suggests. While the risk is low, it should be taken into account by doctors and patients, according to Dana-Farber Cancer Institute scientists and colleagues. The investigators analyzed the findings of 10 clinical trials that included nearly 4,700 patients treated with sorafenib (Nexavar) for kidney and liver cancer; sunitinib (Sutent) for kidney cancer and gastrointestinal stromal tumor; or pazopanib (Votrient) for kidney cancer. These so-called "targeted" drugs are used to stop the growth or spread of cancer by blocking the vascular endothelial growth factor tyrosine kinase receptors in cancer cells, the researchers explained in a Dana-Farber news release. The analysis of the clinical trials revealed that the incidence of fatal complications was 1.5 ... Read more
Related support groups: Votrient, Sutent, Nexavar, Sunitinib, Pazopanib, Sorafenib
Mixed News on Tough-to-Treat Lung Cancer
Posted 10 Jan 2012 by Drugs.com
TUESDAY, Jan. 10 – Dutch researchers report disappointing results from an early clinical trial of the drug Nexavar (sorafenib) in fighting a tough-to-treat form of lung cancer. But, in better news, an experimental drug known as ganetespib showed promise in laboratory and animal experiments. The results of both studies were to be presented Tuesday at an American Association for Cancer Research/International Association for the Study of Lung Cancer meeting in San Diego. In recent years, researchers have made some headway in finding treatments to combat lung cancer, which often doesn't respond well to chemotherapy, explained Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society. Those treatments include drugs such as crizotinib (Xalkori) and erlotinib (Tarceva), which are most effective in tumors that contain certain genetic mutations. However, those drugs tend ... Read more
Related support groups: Lung Cancer, Tarceva, Non-Small Cell Lung Cancer, Nexavar, Xalkori, Small Cell Lung Cancer, Erlotinib, Sorafenib, Crizotinib
Cancer Patients Should Ask Doctors to Use Simple Terms
Posted 28 Sep 2011 by Drugs.com
WEDNESDAY, Sept. 28 – Cancer patients are often faced with many difficult-to-understand treatment choices that can have serious side effects and even mean the difference between life and death. That's why it's crucial that patients insist doctors use plain language in explaining the options, advised Angela Fagerlin, an associate professor of internal medicine at the University of Michigan Medical School and a researcher at the U-M Comprehensive Cancer Center. "People are making life and death decisions that may affect their survival and they need to know what they're getting themselves into. Cancer treatments and tests can be serious. Patients need to know what kind of side effects they might experience as a result of the treatment they undergo," Fagerlin said in a university news release. She and her colleagues outlined a number of tips to help patients get the information they need ... Read more
Related support groups: Cancer, Methotrexate, Provera, Breast Cancer, Lupron, Accutane, Depo-Provera, Prostate Cancer, Tamoxifen, Femara, Arimidex, Lupron Depot, Medroxyprogesterone, Claravis, Fluorouracil
Certain Cancer Drugs Don't Interfere With Flu Vaccine: Study
Posted 28 Jun 2011 by Drugs.com
TUESDAY, June 28 – Cancer patients taking the drugs sunitinib and sorafenib respond to the flu vaccine, which suggests that the drugs don't cause as much damage to the immune system as previously believed, researchers say. The small study included 40 volunteers in the Netherlands, including 16 who were treated with sunitinib and six who were treated with sorafenib. Seven patients with metastatic renal cell (kidney) cancer received neither drug, nor did 11 healthy people. When given a flu vaccine, all of the cancer patients had an antibody response similar to that of the healthy participants. The study appears in the current issue of the journal Clinical Cancer Research. "The exact incidence of influenza in patients with cancer is not known, however, it is definitely higher than in the general population," study leader Dr. Carla van Herpen, a medical oncologist at the Radboud University ... Read more
Related support groups: Sutent, Nexavar, Sunitinib, Sorafenib, Influenza Virus Vaccine, H1n1, Inactivated, Influenza Prophylaxis
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Renal Cell Carcinoma, Thyroid Cancer, Hepatocellular Carcinoma, Hepatic Tumor