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FDA Approves Odomzo (sonidegib) for Locally Advanced Basal Cell Carcinoma

Posted 6 days ago by Drugs.com

July 24, 2015 – The U.S. Food and Drug Administration today approved Odomzo (sonidegib) to treat patients with locally advanced basal cell carcinoma that has recurred following surgery or radiation therapy, or who are not candidates for surgery or radiation therapy. Skin cancer is the most common cancer and basal cell carcinoma accounts for approximately 80 percent of non-melanoma skin cancers. Basal cell carcinoma starts in the top layer of the skin (called the epidermis) and usually develops in areas that have been regularly exposed to the sun and other forms of ultraviolet radiation. According to the National Cancer Institute, the number of new cases of non-melanoma skin cancer appears to be increasing every year. Locally advanced basal cell skin cancer refers to basal cancers that have not spread to other parts of the body, but cannot be curatively treated with local treatments, ... Read more

Related support groups: Basal Cell Carcinoma, Skin Cancer, Sonidegib, Odomzo

New Skin Cancer Drug Odomzo Approved by FDA

Posted 6 days ago by Drugs.com

FRIDAY, July 24, 2015 – A new drug to treat the most common form of skin cancer has been approved by the U.S. Food and Drug Administration. Odomzo (sonidegib) was cleared to treat locally advanced basal cell carcinoma in patients who cannot undergo surgery or radiation therapy, or whose skin cancer has returned after surgery or radiation therapy. Skin cancer is the most common type of cancer, and basal cell carcinoma accounts for about 80 percent of non-melanoma skin cancers. Locally advanced basal cell skin cancer has not spread to other parts of the body, but cannot be cured with surgery or radiation. Odomzo is a once-a-day pill designed to suppress a molecular pathway that is active in basal cell cancers, according to the FDA. The drug's approval was based on a clinical trial that included 66 patients who took 200 milligrams (mg) of Odomzo a day and 128 patients who took 800 mg a ... Read more

Related support groups: Basal Cell Carcinoma, Skin Cancer, Sonidegib, Odomzo

Odomzo Approved for Recurring Basal Cell Carcinoma

Posted 6 days ago by Drugs.com

FRIDAY, July 24, 2015 – Odomzo (sonidegib) has been approved by the U.S. Food and Drug Administration to treat basal cell carcinoma skin cancer that has returned despite surgery or radiation. The treatment is sanctioned for people who are not candidates for additional surgery or radiation. Basal cell carcinoma accounts for about 80 percent of skin cancers that are not melanoma, a more deadly form of the disease. Basal cell starts in the top layer of skin, usually in areas that are most exposed to the sun, the agency said Friday in a news release. The once-daily pill is designed to inhibit a process that promotes the growth of cancerous lesions. The drug's label includes a boxed warning that it may cause death or severe birth defects in a growing fetus. Women who may become pregnant should verify pregnancy status before taking the drug. And both males and females who take Odomzo are ... Read more

Related support groups: Basal Cell Carcinoma, Skin Cancer, Sonidegib, Odomzo

U.S. Oncologists Decry High Cost of Cancer Drugs

Posted 10 days ago by Drugs.com

THURSDAY, July 23, 2015 – Soaring costs for cancer drugs are hurting patient care in the United States, a group of top oncologists claim. "High cancer-drug prices are affecting the care of patients with cancer and our health care system," Dr. Ayalew Tefferi, a hematologist at Mayo Clinic in Rochester, Minn., said in a Mayo news release. Tefferi and his colleagues made a number of recommendations on how to address the problem in a commentary published July 23 in the Mayo Clinic Proceedings. Allowing Medicare to negotiate drug prices is one of the suggestions the team of 118 leading cancer experts offered as a possible solution. Along with their recommendations, the group also expressed support for a patient-based grassroots movement on change.org that is demanding action on the issue. "The average gross household income in the U.S. is about $52,000 per year. For an insured patient with ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Lupron, Accutane, Prostate Cancer, Medroxyprogesterone, Tamoxifen, Arimidex, Lupron Depot, Femara, Tretinoin, Gleevec, Fluorouracil, Rituxan, Colorectal Cancer, Zoladex, Lung Cancer

New Dumb-But-Deadly Trend: Sunburn 'Art'

Posted 17 days ago by Drugs.com

THURSDAY, July 16, 2015 – Sunburns are painful and potentially cancer-causing, but that hasn't stopped them from becoming an increasingly popular means of artistic expression. Experts are now speaking out against "sunburn art," a new social media trend in which people use stencils or strategically applied sunblock to create a do-it-yourself temporary sunburn tattoo on their bodies. Participants then take pictures of their creations and post them on sites such as Twitter and Facebook. The trend is worrisome enough that the Skin Cancer Foundation has issued an official position on sunburn art, warning of the health risks associated with tanned or sunburned skin. "Sunburns cause DNA damage to the skin, accelerate skin aging, and increase your lifetime skin cancer risk," the statement reads. "In fact, sustaining five or more sunburns in youth increases lifetime melanoma risk by 80 percent. ... Read more

Related support groups: Basal Cell Carcinoma, Sunburn, Skin Cancer, Melanoma, Melanoma - Metastatic, Squamous Cell Carcinoma, History - Skin Cancer

Indoor Tanning Rates Decline As Cancer Warnings Mount

Posted 1 Jul 2015 by Drugs.com

WEDNESDAY, July 1, 2015 – Heeding warnings about increased cancer risks, a growing number of American adults are saying no to indoor tanning, a new government analysis suggests. The percentage of adults who frequented indoor tanning salons dropped from 5.5 percent in 2010 to slightly over 4 percent in 2013, according to results of the National Health Interview Survey, a poll of more than 59,000 adults. "Roughly 2 million fewer adults are engaging in indoor tanning, which is definitely encouraging, given the associated health risks," noted study author Gery Guy Jr., a health economist with the division of cancer prevention and control at the U.S. Centers for Disease Control and Prevention. "The bad news is that even with this reduction, there's still about 10 million adults who continue to indoor tan, which clearly indicates that more efforts are needed to get the message across that ... Read more

Related support groups: Basal Cell Carcinoma, Sunburn, Skin Cancer, Melanoma, Melanoma - Metastatic, Squamous Cell Carcinoma, History - Skin Cancer

Graphic Warnings May Work Best to Keep Women From Tanning Beds

Posted 11 Jun 2015 by Drugs.com

THURSDAY, June 11, 2015 – Disturbing images of skin cancer are more likely to make young women reconsider indoor tanning than the text-only warnings currently required by U.S. regulators, a new study suggests. According to a team at Georgetown University Medical Center in Washington, D.C., nearly 30 percent of young, white women in the United States use indoor tanning each year, and half of them use indoor tanning 10 times or more a year. "In terms of a public health issue, indoor tanning is a perfect storm – young people, primarily women, indoor tan, which raises their risk of potentially deadly skin cancer. Yet, there are few prevention efforts targeting young adult women," lead researcher Darren Mays, an assistant professor of oncology at Georgetown Lombardi Comprehensive Cancer Center, said in a center news release. Currently, the U.S. Food and Drug Administration requires indoor ... Read more

Related support groups: Basal Cell Carcinoma, Sunburn, Skin Cancer, Melanoma, Melanoma - Metastatic, Squamous Cell Carcinoma, Photoaging of the Skin, Dermatoheliosis, History - Skin Cancer

Online Searches for 'Skin Cancer' Go Up in Summer

Posted 10 Jun 2015 by Drugs.com

WEDNESDAY, June 10, 2015 – When summer hits the United States and sunseekers mobilize, online searches for "skin cancer" rise, a new study shows. However, it's not clear if the higher search rates mean more cancers are being detected early, said researchers reporting online June 10 in JAMA Dermatology. Researchers led by Dr. Kyle Amber, of MacNeal Hospital in Berwyn, Ill., tracked Google searches for the terms "skin cancer" and "melanoma" in the United States between 2010 and 2014. They found a spike in these types of Web searches during the summer, and that summertime bump remained relatively stable over the entire study period, the team said. Nevada had the highest number of searches for skin cancer, while Pennsylvania had the highest number of searches for melanoma, Amber's group said. The finding might be of use in the war against UV ray exposure and related skin cancers, the ... Read more

Related support groups: Basal Cell Carcinoma, Skin Cancer, Melanoma, Melanoma - Metastatic, Squamous Cell Carcinoma, History - Skin Cancer

Health Tip: Protect Against Skin Cancer

Posted 9 Jun 2015 by Drugs.com

-- A routine regimen of protection can help prevent you from getting skin cancer. The American Academy of Dermatology suggests: Cover all exposed skin with a broad-spectrum sunscreen with SPF of at least 30 every day, even when cold or cloudy. Make sure you use enough sunscreen. Be sure to cover the tops of your ears and feet, the back of your neck and, if balding, the top of your head. Stay in the shade between 10 a.m. and 2 p.m., when the sun is strongest. Wear sunglasses, a wide-brimmed hat, long pants and a long-sleeved shirt. Be particularly careful around water and snow, since reflection can make the sun's rays more intense. Read more

Related support groups: Basal Cell Carcinoma, Skin Cancer, Melanoma, Melanoma - Metastatic, Squamous Cell Carcinoma, History - Skin Cancer

Most Americans Still Not Using Sunscreen

Posted 19 May 2015 by Drugs.com

TUESDAY, May 19, 2015 – Most Americans still don't regularly use sunscreen to help prevent exposure to the sun's cancer-causing rays, a new study reveals. When used as recommended, sunscreen has been shown to reduce risk for all types of skin cancer and prevent or delay signs of aging, the researchers explained. But their 2013 survey found only 14 percent of men and 30 percent of women regularly use sunscreen both on their face and other exposed skin. The study also showed that more than 40 percent of men and 27 percent of women never use sunscreen on their face or other areas of exposed skin when outdoors for an hour or more. Women are probably ahead of the game since many face creams contain sun protection factor (SPF), said Dawn Holman, a behavioral scientist at the U.S. Centers for Disease Control and Prevention and lead author of the study. But even if they are more knowledgeable ... Read more

Related support groups: Basal Cell Carcinoma, Sunburn, Skin Cancer, Melanoma, Melanoma - Metastatic, Squamous Cell Carcinoma, History - Skin Cancer

Too Many Americans Neglect Backs in Skin Cancer Prevention

Posted 4 May 2015 by Drugs.com

MONDAY, May 4, 2015 – A new survey finds that many people in the United States are forgetting their backs when they try to be forward-thinking about skin cancer prevention. Experts at the American Academy of Dermatology, which sponsored the survey, note that the back is a common site for melanoma, a potentially deadly skin cancer. However, of the more than 1,000 Americans polled, over a third said they rarely or never apply sunscreen to their backs when they're in the sun. Almost half (43 percent) also said that they never or rarely ask anyone to assist applying sunscreen to their backs. Men weren't as willing as women to apply sunscreen to their backs or ask someone else for help, and they were twice as likely to be uncomfortable about the whole idea. Overall, 40 percent of men and 33 percent of women surveyed said they rarely or never apply sunscreen to their backs. One expert said ... Read more

Related support groups: Basal Cell Carcinoma, Sunburn, Skin Cancer, Melanoma, Squamous Cell Carcinoma, Photoaging of the Skin, Dermatoheliosis, History - Skin Cancer

Skin Cancer Rates Rise for Hispanic, Asian Women

Posted 20 Mar 2015 by Drugs.com

FRIDAY, March 20, 2015 – While most white people who develop skin cancer are older men, the reverse is true in Asian and Hispanic populations, a new study suggests. Researchers contend that shifting preferences for tanning among Asians and Hispanics in the United States – along with the belief that their darker skin protects them from the sun's harmful rays – may be contributing to rising skin cancer rates in both groups. "I think the main point we were trying to bring home is that ethnic skin is not really thought of as at risk for skin cancer, but all ethnicities need to be mindful and diligent about getting their skin checked and protecting themselves from the sun," said study author Dr. Arisa Ortiz, an assistant clinical professor of dermatology at University of California, San Diego (UCSD). The study is to be presented Friday at the American Academy of Dermatology's annual ... Read more

Related support groups: Skin Cancer

Sun's Damage Lingers Long After Dark

Posted 19 Feb 2015 by Drugs.com

THURSDAY, Feb. 19, 2015 – Skin damage caused by ultraviolet (UV) radiation continues long after you get out of the sun, even in the dark, a new study says. Researchers explain that UV light from the sun or tanning beds can damage DNA in melanocytes. Melanocytes are cells in the skin that make the substance called melanin. Melanin gives skin its color. Damage to melanocytes is a major cause of skin cancer, according to the researchers. It was thought that melanin protected the skin by blocking UV light, but this study found that melanin has both protective and harmful effects. Researchers exposed mouse and human melanocytes to UV radiation. In melanocytes with melanin, DNA damage occurred not only immediately, but also hours after UV exposure ended. In melanocytes that didn't have melanin, the damage occurred only during UV exposure. "If you look inside adult skin, melanin does protect ... Read more

Related support groups: Sunburn, Skin Cancer, Photoaging of the Skin, Dermatoheliosis

Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds

Posted 18 Dec 2014 by Drugs.com

THURSDAY, Dec. 18, 2014 – Common painkillers, including ibuprofen, might slightly reduce your risk of developing a form of skin cancer, researchers say. Use of ibuprofen (Advil, Motrin) and naproxen (Aleve) appear to reduce the risk of squamous cell skin cancer by 15 percent, the researchers concluded after reviewing nine prior studies. Squamous cell skin cancer is usually caused by sun exposure. These painkillers "have potential as part of a skin cancer-prevention strategy," said review co-author Catherine Olsen, a senior research officer with QIMR Berghofer Medical Research Institute in Brisbane, Queensland, Australia. But Olsen and other experts aren't ready to recommend popping these or other nonsteroidal anti-inflammatory drugs (NSAIDs) to prevent skin cancer. For one thing, these drugs are associated with risks of their own. "Don't rely on aspirin or other nonsteroidal ... Read more

Related support groups: Ibuprofen, Naproxen, Advil, Aleve, Motrin, Skin Cancer, Vicoprofen, Advil PM, Naprosyn, Vimovo, Treximet, Advil Cold and Sinus, Squamous Cell Carcinoma, Naprelan, Naprelan '375', Hydrocodone/Ibuprofen, Anaprox, Motrin PM, Duexis, Ibuprofen PMR

Flying Time Could Raise Skin Cancer Risks for Pilots

Posted 18 Dec 2014 by Drugs.com

WEDNESDAY, Dec. 17, 2014 – Airline pilots get as much exposure to cancer-causing UV rays in an hourlong flight as they would during 20 minutes in a tanning bed, new research finds. The study, led by Dr. Martina Sanlorenzo, from the University of California, San Francisco, found that airplane windshields do not completely block harmful ultraviolet-A (UV-A) rays from the sun. This type of radiation can boost the risk of deadly melanomas, the researchers noted. Based on the findings, "we strongly recommend the use of sunscreens and periodical skin checks for pilots and cabin crew," the authors wrote in the Dec. 17 online issue of JAMA Dermatology. In the study, Sanlorenzo's team measured the amount of UV-A radiation in the pilot seat at ground level and at various altitudes during flight. The exposure was measured in San Jose, Calif., and in Las Vegas at about midday in April. Pilots ... Read more

Related support groups: Skin Cancer

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