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Related terms: Complex Partial Seizure, Fits, Absence Seizure

Childhood Whooping Cough Tied to Small Rise in Epilepsy Risk

Posted 3 Nov 2015 by

TUESDAY, Nov. 3, 2015 – Whooping cough may be tied to a slightly increased risk for a young child to develop epilepsy, a new study finds. Whooping cough (pertussis) is relatively rare in the United States, however. And the absolute risk to any one child of getting epilepsy remains "low," said Dr. Meghan Fleming, a neurologist at Lenox Hill Hospital in New York City. She reviewed the findings from the new study. According to background information in the study, vaccination can prevent whooping cough, but roughly 16 million cases of the disease still occur worldwide each year. There were nearly 50,000 whooping cough cases reported in the United States in 2012, the study authors noted. In the new study, a team led by Dr. Morten Olsen of Aarhus University Hospital in Denmark looked at 4,700 Danish children with whooping cough. The children in the study were born between 1978 and 2011 and ... Read more

Related support groups: Seizures, Epilepsy, Seizure Prevention, Seizure Prophylaxis, Pertussis, Kinrix, Boostrix (Tdap), Pertussis, Acellular, Diphtheria Toxoid/Pertussis, Acellular/Poliovirus Vaccine, Inactivated/Tetanus Toxoid, Daptacel (DTaP), Tripedia (DTaP), Vaccination and Prophlaxis, Pediarix, Tetramune, Diphtheria Toxoid/Haemophilus B Conjugate (Prp-T) Vaccine/Pertussis, Acellular/Poliovirus Vaccine, Inactivated/Tetanus Toxoid, Trihibit, Diphtheria Toxoid/hepatitis B Pediatric Vaccine/pertussis, Acellular/poliovirus Vaccine, Inactivated/tetanus Toxoid, DTP Vaccine, Diphtheria Toxoid/Haemophilus B Conjugate (Hboc) Vaccine/Pertussis, Whole Cell/Tetanus Toxoid, Quadracel

Gene May Boost Death Risk for People With Mild Epilepsy

Posted 23 Oct 2015 by

FRIDAY, Oct. 23, 2015 – Researchers say they've identified a gene mutation that might increase the risk of sudden death in people with mild epilepsy. The researchers studied a four-generation family with nine members who had epilepsy caused by a mutation of the DEPDC5 gene. This form of epilepsy is considered mild. But, two of the family members suffered what is known as sudden unexpected death in epilepsy (SUDEP), which is statistically significant for the small number of people in the study, according to the researchers in the Adult Genetic Epilepsy Program of the Krembil Neuroscience Center in Toronto. But the study did not prove that the gene mutation caused the increased risk for SUDEP. SUDEP is when a person with epilepsy who is otherwise healthy dies unexpectedly and without an apparent cause. About one in 1,000 people with epilepsy die of SUDEP each year, the researchers said. ... Read more

Related support groups: Seizures, Epilepsy, Diagnosis and Investigation

Could Marijuana Chemical Help Ease Epilepsy?

Posted 9 Sep 2015 by

WEDNESDAY, Sept. 9, 2015 – A chemical found in marijuana might help prevent epilepsy seizures, but drug laws have hampered research efforts, a new study says. Cannabidiol is one of the main active chemical compounds found in pot. But it doesn't make people high, the study authors said. Cannabidiol has already been shown to prevent seizures in animal studies and in one ongoing human trial, said lead author Dr. Daniel Friedman, a neurologist and epilepsy specialist at NYU Langone Medical Center in New York City. But legally, marijuana is considered a Schedule I controlled substance. That means the U.S. Drug Enforcement Agency classifies it as a drug with "no currently accepted medical use and a high potential for abuse." That classification makes it difficult to pursue large-scale trials that could prove cannabidiol's safety and effectiveness in epilepsy, Friedman said. "Right now, the ... Read more

Related support groups: Seizures, Epilepsy, Seizure Prevention, Seizure Prophylaxis, Cannabis, Status Epilepticus

Music Therapy Might One Day Help People With Epilepsy

Posted 9 Aug 2015 by

SUNDAY, Aug. 9, 2015 – Music therapy might someday help people with epilepsy, a new study suggests. About 80 percent of epilepsy patients have temporal lobe epilepsy, in which seizures originate in the temporal lobe of the brain. Music is processed in the auditory cortex, located in the same region of the brain, which is why researchers from Ohio State University's Wexner Medical Center wanted to study the connection. The study authors said that the brains of epilepsy patients appear to react to music differently from the brains of people without the disorder. "We believe that music could potentially be used as an intervention to help people with epilepsy," Christine Charyton, adjunct assistant professor and visiting assistant professor of neurology, said in an American Psychological Association (APA) news release. Charyton plans to present the research Sunday at the APA's annual ... Read more

Related support groups: Seizures, Epilepsy, Seizure Prevention, Seizure Prophylaxis, Status Epilepticus

FDA Approves Spritam (levetiracetam) as the First 3D Printed Drug Product

Posted 4 Aug 2015 by

BLUE ASH, Ohio, August 3, 2015 – Aprecia Pharmaceuticals Company today announced that the U.S. Food and Drug Administration (FDA) has approved Spritam (levetiracetam) for oral use as a prescription adjunctive therapy in the treatment of partial onset seizures, myoclonic seizures and primary generalized tonic-clonic seizures in adults and children with epilepsy.1 Spritam utilizes Aprecia's proprietary ZipDose® Technology platform, a groundbreaking advance that uses three-dimensional printing (3DP) to produce a porous formulation that rapidly disintegrates with a sip of liquid.1 While 3DP has been used previously to manufacture medical devices, this approval marks the first time a drug product manufactured with this technology has been approved by the FDA. “By combining 3DP technology with a highly-prescribed epilepsy treatment,2 Spritam is designed to fill a need for patients who st ... Read more

Related support groups: Seizures, Epilepsy, Levetiracetam, Spritam

FDA Approves First Pill Made by 3D Printing

Posted 4 Aug 2015 by

TUESDAY, Aug. 4, 2015 – The age of 3D printing has come to the drug industry, with the U.S. Food and Drug Administration on Monday approving the first pill made with the technology. The agency approved the prescription drug Spritam (levetiracetam) as a 3D-printed pill, to be taken with other medicines for seizures in certain children and adults with epilepsy. According to a news release from Ohio-based Aprecia Pharmaceuticals, the drug is made using a 3D printing method called ZipDose Technology, which produces a porous pill that rapidly disintegrates with a sip of liquid. 3D printing has already been used to make medical devices, but Spritam is the first 3D-printed drug to be approved for sale in the United States. It is expected to be available early next year. Experts say 3D printing of pills could usher in an era where drugs can be custom-ordered, based on specific patient needs, ... Read more

Related support groups: Seizures, Keppra, Seizure Prevention, Levetiracetam, Seizure Prophylaxis, Keppra XR, Elepsia XR, Spritam

Epilepsy Linked to Risks During Childbirth, Study Finds

Posted 6 Jul 2015 by

MONDAY, July 6, 2015 – Pregnant women with epilepsy may have more than a higher risk of dying during delivery, a new study suggests. "Specifically, there were 80 deaths per 100,000 women with epilepsy versus six deaths per 100,000 in women without epilepsy," said lead researcher Sarah MacDonald, from the department of epidemiology at Harvard T.H. Chan School of Public Health in Boston. However, although the so-called "relative risk" of death during delivery among women with epilepsy was high, it's still a rare occurrence, MacDonald stressed. The researchers also found that the risk of delivery complications was higher among women with epilepsy. "We also found that women with epilepsy were at increased risk for cesarean delivery, prolonged hospital stay, preeclampsia [pregnancy-related high blood pressure], preterm labor and stillbirth," she said. Although the study found a link between ... Read more

Related support groups: Seizures, Epilepsy, Seizure Prevention, Delivery, Seizure Prophylaxis, Premature Labor, Labor Induction, Labor and Delivery including Augmentation

FDA Approves Fycompa as Adjunctive Treatment for Primary Generalized Tonic-Clonic Seizures

Posted 30 Jun 2015 by

Tokyo, June 22, 2015 – Eisai Co., Ltd. announced today that its U.S. subsidiary Eisai Inc. has received approval from the U.S. Food and Drug Administration (FDA) for an indication expansion regarding the use of its in-house developed antiepileptic agent Fycompa (perampanel hydrate) as an adjunctive treatment of primary generalized tonic-clonic (PGTC) seizures in patients with epilepsy 12 years of age and older. The FDA's decision to approve the indication expansion was based on a placebo-controlled clinical phase III study (Study 332) of Fycompa in 164 patients aged 12 years and older with PGTC seizures. In the study, a statistically significant reduction in PGTC seizure frequency was observed in the Fycompa group compared with placebo (Fycompa: -76.5%, placebo: -38.4%, p Read more

Related support groups: Seizures, Epilepsy, Seizure, Fycompa, Perampanel

Online Community Helps People Manage Epilepsy

Posted 17 Jun 2015 by

WEDNESDAY, June 17, 2015 – Being part of an online community may help people with epilepsy better manage their disease, a new study suggests. "Epilepsy is a complicated disease, and many people who live with it are not well informed about their condition and how to manage it. Formal, in-person education can be expensive and difficult to coordinate, especially when people live in rural areas. We wanted to see whether an online community could benefit people with epilepsy," study author Dr. John Hixson, of the University of California San Francisco and the San Francisco VA Medical Center, said in a news release from the journal Neurology. The research included almost 100 epilepsy patients who participated in an online forum called PatientsLikeMe. In the forum, people with epilepsy can share information and support. It also has digital tools for tracking seizures, symptoms and ... Read more

Related support groups: Seizures, Epilepsy, Seizure Prevention, Seizure Prophylaxis

FDA Medwatch Alert: Potiga (ezogabine): Drug Safety Communication - FDA Determines 2013 Labeling Adequate to Manage Risks of Retinal Abnormalities, Potential Vision Loss, and Skin Discoloration

Posted 16 Jun 2015 by

ISSUE: Based on reviews of additional safety reports from patients treated with the anti-seizure drug Potiga (ezogabine), the FDA has determined that the potential risks of vision loss due to pigment changes in the retina and of skin discoloration can be adequately managed by following the current recommendations in the Potiga labeling. To further explore any potential long-term consequences of these pigment changes, FDA has required the Potiga manufacturer, GlaxoSmithKline, to conduct a long-term observational study. FDA review of additional safety reports does not indicate that the pigment changes in the retina observed in some patients affect vision. Skin discoloration associated with the use of Potiga appears to be a cosmetic effect and does not appear to be associated with more serious adverse effects. Therefore, a modification of the Risk Evaluation and Mitigation Strategy (REMS) ... Read more

Related support groups: Seizures, Potiga, Ezogabine

FDA Approves Expanded Indication for Qudexy XR (Topiramate) for Pediatric Patients

Posted 3 Jun 2015 by

Maple Grove, MN – June 1, 2015 – Upsher-Smith Laboratories, Inc. (Upsher-Smith) announced that it has received U.S. Food and Drug Administration (FDA) approval of a supplemental new drug application (sNDA) for Qudexy XR (topiramate) extended-release capsules for use as initial monotherapy in patients two years of age and older who are experiencing partial-onset seizures (POS) or primary generalized tonic-clonic seizures. Qudexy XR capsules are the only once-daily extended-release topiramate product to have received this expanded indication and to be approved for administration by sprinkling their contents onto soft food, making them a useful option for young children who may have difficulty swallowing whole capsules or tablets. Qudexy XR is a once-daily, broad-spectrum antiepileptic drug specifically engineered to deliver a smooth pharmacokinetic profile. “The expanded indication give ... Read more

Related support groups: Seizures, Topiramate

Health Tip: Travel Safely in the Air

Posted 12 May 2015 by

-- A little preparation can help you stay healthy and safe when traveling by plane. The American Academy of Family Physicians recommends: Packing all necessary medications in a carry-on bag. Talk to your doctor about whether you should change your medication regimen while traveling. Pack some extras, in case your trip is extended. If you have a chronic illness such as epilepsy or diabetes, carry an identification card with your doctor's contact information and a list of your medications. Drink non-alcoholic, no-caffeine beverages to avoid dehydration. If you tend to have ear pain, take a decongestant before you fly, or chew gum. Stretch calves frequently, and walk around when it is safe to do so. Read more

Related support groups: Diabetes, Type 2, Seizures, Epilepsy, Diabetes, Type 1, Seizure Prevention, Dehydration, Seizure Prophylaxis, Diabetes Mellitus

High-Pitched Sounds May Trigger Seizures in Cats

Posted 28 Apr 2015 by

TUESDAY, April 28, 2015 – High-pitched sounds may trigger seizures in cats, particularly older felines, a new study says. Although many veterinarians are unaware of this connection, the louder the sound, the more severe the seizure, British researchers contend. Cat owners around the world were surveyed by scientists at University College London's School of Pharmacy, to find out if their pets had seizures or involuntary jerking motions in response to certain sounds. The researchers found hundreds of people noticed this behavior in their cats. They also found local vets had no answers for why cats reacted this way. The researchers compiled detailed information on 96 cats, including the type of seizures they had, how long they lasted, and the sound that seemed to trigger the reaction. The study, published April 27 in the Journal of Feline Medicine and Surgery, found some cats do seemingly ... Read more

Related support groups: Seizures, Keppra, Seizure Prevention, Levetiracetam, Seizure Prophylaxis, Keppra XR

Medical Groups Issue Guidelines for Treating First Seizure

Posted 20 Apr 2015 by

MONDAY, April 20, 2015 – One in 10 people worldwide will have a seizure in his or her lifetime, experts say. Now, two medical groups have issued a new guideline on how to treat them. The decision to treat a patient after a first seizure is complex because doctors must weigh the risks and benefits on an individual basis, according to the American Academy of Neurology and the American Epilepsy Society. After a review of all available evidence, the two organizations concluded that taking epilepsy drugs immediately after a first seizure may reduce the risk of more seizures. The guideline, published in the April 21 issue of the journal Neurology, will be presented this week at the annual meeting of the American Academy of Neurology, in Washington, D.C. "This is a valuable new guideline that could change the approach many doctors take to treating a first seizure and could improve patients' ... Read more

Related support groups: Seizures, Seizure Prevention, Seizure Prophylaxis

Liquid Medical Marijuana Shows Promise Against Severe Epilepsy

Posted 13 Apr 2015 by

MONDAY, April 13, 2015 – A liquid form of medical marijuana may help people with severe epilepsy that does not respond to other treatments, according to a new report. The study included 213 child and adult patients with 12 different types of severe epilepsy. Some of them had Dravet syndrome and Lennox-Gastaut syndrome, which are types of epilepsy that can cause intellectual disability and lifelong seizures. The patients took a liquid form of medical marijuana, called cannabidiol, daily for 12 weeks. Among the 137 people who completed the study, the number of seizures fell by an average of 54 percent, according to a team led by Dr. Orrin Devinsky, of New York University Langone Comprehensive Epilepsy Center in New York City. Among the 23 patients with Dravet syndrome who completed the study, the number of convulsive seizures fell by 53 percent, the investigators found. The 11 patients ... Read more

Related support groups: Seizures, Epilepsy, Seizure Prevention, Seizure Prophylaxis

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