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Steroids May Help Some With Sciatica

Posted 16 Apr 2012 by Drugs.com

MONDAY, April 16 – New research suggests that epidural steroids provided better relief for some patients with sciatica, a searing pain that shoots from the lower back straight down the leg, than Enbrel, a newer type of anti-inflammatory drug. Yet the differences were "modest" and did not reach statistical significance. And while more patients reported pain relief one month after receiving epidural steroids, the relief didn't necessarily last. At six months, steroids weren't any better than Enbrel (etanercept) or a third treatment tested, injections containing saline and a local anesthetic. "We found a pretty strong suggestion that steroids were better than both of the other treatments, and the etanercept wasn't better than saline, in the short-term," said study author Dr. Steven Cohen, a professor of anesthesia at Uniformed Services University of the Health Sciences and director of ... Read more

Related support groups: Prednisone, Enbrel, Sciatica, Prednisolone, Methylprednisolone, Cortisone, Hydrocortisone, Medrol, Triamcinolone, Dexamethasone, Betamethasone, Decadron, Budesonide, Entocort, Solu-Medrol, Cortef, Entocort EC, Celestone, Depo-Medrol, Orapred

Scientists Discover Substance That Causes Pain

Posted 28 Apr 2010 by Drugs.com

WEDNESDAY, April 28 – The human body produces a substance similar to capsaicin – which makes chili peppers hot – at sites of pain, and blocking production of this substance can ease pain, a new study shows. The findings may lead to the development of non-addictive painkillers, according to the researchers at the University of Texas Health Science Center in San Antonio. In work with mice, the scientists found that a family of fatty acids called oxidized linoleic acid metabolites (OLAMs) play an important role in the biology of pain. "This is a major breakthrough in understanding the mechanisms of pain and how to more effectively treat it," senior investigator Kenneth Hargreaves, chair of the Department of Endodontics in the Dental School at the UT Health Sciences Center, said in an UT news release. "These data demonstrate, for the first time, that OLAMs constitute a new family of ... Read more

Related support groups: Pain, Back Pain, Headache, Fibromyalgia, Migraine, Muscle Pain, Neuralgia, Breakthrough Pain, Migraine Prevention, Sciatica, Neck Pain, Herniated disc, Scoliosis, Cluster Headaches, Migraine Prophylaxis, Spondylolisthesis, Frozen Shoulder, New Daily Persistent Headache, Costochondritis, Epicondylitis - Tennis Elbow

Minimally Invasive Surgery Not Better for Sciatica

Posted 7 Jul 2009 by Drugs.com

TUESDAY, July 7 – Minimally invasive surgery for the excruciating back pain that can be caused by sciatica didn't work as well as the conventional procedure in a Dutch study. "The expected treatment benefit of a faster rate of recovery from sciatica after tubular diskectomy could not be reproduced by this double-blind study," according to a report in the July 8 issue of the Journal of the American Medical Association. Orthopedic surgeons at the Medical Center Haaglanden studied 328 people who underwent surgery for sciatic pain, and found that "the overall differences in pain intensity and recovery rates favored the conventional microdiskectomy." Surgery is done to remove the portion of a disk that has ruptured and causes pain by pressing on the sciatic nerve. The older method, microdiskectomy, is done through a larger incision than that used for transmuscular tubular diskectomy, the ... Read more

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