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Related terms: Catatonic Schizophrenia, Disorganized Schizophrenia, Paranoid Schizophrenia, Residual Schizophrenia, Schizophrenia, catatonic, Schizophrenia, disorganized, Schizophrenia, paranoid, Schizophrenia, residual, Schizophrenia, undifferentiated, Undifferentiated Schizophrenia

Scientists Uncover Clues to Origins of Schizophrenia

Posted 15 days ago by Drugs.com

WEDNESDAY, Jan. 27, 2016 – Some people might develop schizophrenia when a normal process of brain development goes haywire in adolescence and early adulthood, Harvard researchers report. Everyone undergoes what is called "synaptic pruning" as they move into adulthood, explained study author Steven McCarroll, director of genetics for the Broad Institute's Stanley Center for Psychiatric Research and an associate professor of genetics at Harvard Medical School in Boston. It's how extra brain cells and synapses (the junctions where nerve signals cross from one brain cell to the next) are eliminated in the cerebral cortex, to increase the efficiency of function, he said. But a gene that contributes to synaptic pruning may increase a person's risk of schizophrenia if certain mutations cause things to go wrong, McCarroll and his colleagues explained. "Somehow, this biological process becomes ... Read more

Related support groups: Schizophrenia, Schizoaffective Disorder, Diagnosis and Investigation

Mouse Study May Offer Clues to Mysteries of Schizophrenia

Posted 6 Jan 2016 by Drugs.com

WEDNESDAY, Jan. 6, 2016 – Results of experiments with mice may help shed light on some of the harder-to-treat symptoms of schizophrenia in humans, a new study suggests. Schizophrenia is a severe mental illness that affects about one in every 100 adults worldwide, according to background notes with the study. Researchers at Columbia University Medical Center in New York City found that the loss of certain cells in a previously unexplored area of the brain's memory center may be linked with the disabling disease. Specifically, the investigators said a decrease in the number of so-called inhibitory neurons in a tiny area of the hippocampus may play a role in stubborn symptoms such as social withdrawal, low levels of motivation and emotional problems. It's long been thought that schizophrenia originates in the hippocampus, the brain region that handles memory. Nearly every part of the ... Read more

Related support groups: Schizophrenia, Schizoaffective Disorder

Bullying Can Leave Lasting Mental Scars

Posted 9 Dec 2015 by Drugs.com

WEDNESDAY, Dec. 9, 2015 – Bullying can lead to lasting psychological effects for both victims and tormentors, researchers report. More than 20 percent of children who have suffered bullying are prone to depression serious enough to require medical help by their late 20s, researchers from Finland said. "Frequent victimization at age 8 is associated with adult psychiatric disorders needing treatment," said lead researcher Dr. Andre Sourander, a professor in the department of child psychiatry at the University of Turku. Besides depression, researchers found that bullying or being bullied were associated with psychosis, anxiety, and drug and alcohol abuse. "We need to understand the importance of early peer and school experiences for children," Sourander said. "We should integrate a mental health perspective to anti-bullying campaigns, because early intervention can prevent long-term ... Read more

Related support groups: Depression, Anxiety, Generalized Anxiety Disorder, Bipolar Disorder, Panic Disorder, Anxiety and Stress, Opiate Dependence, Obsessive Compulsive Disorder, Opiate Withdrawal, Major Depressive Disorder, Schizophrenia, Mania, Borderline Personality Disorder, Schizoaffective Disorder, Paranoid Disorder, Drug Dependence, Psychosis, Alcohol Dependence, Agitation, Alcohol Withdrawal

Drug Helps Those With Tough-to-Treat Schizophrenia: Study

Posted 25 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 25, 2015 – The drug clozapine reduces symptoms in schizophrenia patients who don't benefit from other antipsychotic medications, a new study indicates. The finding, culled from an analysis of Medicaid data on more than 6,200 patients with treatment-resistant schizophrenia, was published recently in the American Journal of Psychiatry. "These results give clinicians important guidance for how to help an extremely vulnerable group of people," said study author Dr. T. Scott Stroup, a professor of psychiatry at Columbia University Medical Center in New York City and a research psychiatrist at New York State Psychiatric Institute. "By helping individuals with treatment-resistant schizophrenia get effective treatment sooner, we can expect better outcomes," Stroup said in a Columbia news release. Antipsychotic drugs relieve symptoms in most people with schizophrenia, but up to ... Read more

Related support groups: Seroquel, Abilify, Schizophrenia, Risperdal, Latuda, Zyprexa, Risperidone, Schizoaffective Disorder, Geodon, Saphris, Seroquel XR, Quetiapine, Psychosis, Agitation, Olanzapine, Invega, Psychiatric Disorders, Clozapine, Aripiprazole, Clozaril

Almost 1 in 10 Americans Has Lifelong Drug Problem

Posted 18 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 18, 2015 – Nearly one in 10 Americans has some type of lifelong drug use disorder, a new federal government survey finds. But only a quarter of them get the treatment they need, researchers said. The findings stem from a large U.S. National Institutes of Health survey. It's the first survey based on updated mental health guidelines that set a higher bar for diagnosing drug addiction than previous guidelines. "But the seriousness and persistence of the situation doesn't appear to have changed all that drastically since our last look at this," said study lead author Bridget Grant. "What we see," Grant added, "is that a little over 23 million Americans are directly affected with a lifelong problem. And many more are affected when you consider that the issue involves not just the user but also the user's family and social network. And on top of that we also see that ... Read more

Related support groups: Depression, Anxiety, Generalized Anxiety Disorder, Bipolar Disorder, Panic Disorder, Anxiety and Stress, Opiate Dependence, Obsessive Compulsive Disorder, Major Depressive Disorder, Social Anxiety Disorder, Schizophrenia, Mania, Borderline Personality Disorder, Schizoaffective Disorder, Paranoid Disorder, Drug Dependence, Psychosis, Agitation, Psychiatric Disorders, Dysthymia

Brain Differences May Explain Why Some With Schizophrenia Hallucinate

Posted 17 Nov 2015 by Drugs.com

TUESDAY, Nov. 17, 2015 – Researchers believe they've identified brain structure differences that increase the risk of hallucinations in people with schizophrenia. "Hallucinations are very complex phenomena that are a hallmark of mental illness and, in different forms, are also quite common across the general population," said study first author Jane Garrison, from the University of Cambridge in England. "There is likely to be more than one explanation for why they arise, but this finding seems to help explain why some people experience things that are not actually real," she said in a university news release. The researchers analyzed brain scans of schizophrenia patients and people without the mental illness. They found that schizophrenia patients with hallucinations had structural differences in a certain part of the brain compared to patients who did not hallucinate and people ... Read more

Related support groups: Schizophrenia, Schizoaffective Disorder

Computer-Based Psychotherapy Not as Effective as Standard Care

Posted 12 Nov 2015 by Drugs.com

THURSDAY, Nov. 12, 2015 – Computer-assisted cognitive behavioral therapy probably won't replace standard person-to-person therapy any time soon, new research suggests. The British study found that people did not follow through on computer-assisted therapy. Fewer than one in five completed six computer sessions, the researchers reported. Cognitive behavioral therapy – a form of talk therapy – is an effective treatment for depression. However, in-person therapy is not always available, so computer-assisted therapy was developed as a substitute. But until now, the effectiveness of computer-assisted therapy hadn't been studied. The study included almost 700 British patients with depression who were randomly assigned to receive either standard care from their doctor or standard care with one of two computer-assisted therapy packages – one a commercial product and the other a free online ... Read more

Related support groups: Depression, Anxiety, Generalized Anxiety Disorder, Bipolar Disorder, Panic Disorder, Anxiety and Stress, Obsessive Compulsive Disorder, Post Traumatic Stress Disorder, Major Depressive Disorder, Social Anxiety Disorder, Schizophrenia, Mania, Borderline Personality Disorder, Schizoaffective Disorder, Paranoid Disorder, Psychosis, Agitation, Psychiatric Disorders, Dysthymia, Seasonal Affective Disorder

Too Few Psychiatric Patients Screened for Diabetes: Study

Posted 11 Nov 2015 by Drugs.com

WEDNESDAY, Nov. 11, 2015 – Despite guidelines, diabetes screening rates are low among adults with severe mental illness who take antipsychotic medications, researchers find. In a new California study, fewer than one-third of mental health patients were screened for type 2 diabetes, despite an elevated risk for the disorder, the researchers reported in the Nov. 9 online edition of the journal JAMA Internal Medicine. Treatment with antipsychotic drugs contributes to this risk, the researchers explained. This class of drugs includes clozapine (Clozaril), olanzapine (Zyprexa) and risperidone (Risperdal), among others. Anyone taking them should undergo diabetes screening every year, the American Diabetes Association says. These drugs often cause weight gain, a contributing factor to type 2 diabetes, the study authors noted in a journal news release. "To improve care for persons with serious ... Read more

Related support groups: Depression, Anxiety, Generalized Anxiety Disorder, Bipolar Disorder, Panic Disorder, Diabetes, Type 2, Anxiety and Stress, Obsessive Compulsive Disorder, Attention Deficit Hyperactivity Disorder (ADHD), Post Traumatic Stress Disorder, Major Depressive Disorder, Social Anxiety Disorder, Schizophrenia, Mania, Borderline Personality Disorder, Paranoid Disorder, Psychosis, Binge Eating Disorder, Agitation, Psychiatric Disorders

People With Schizophrenia Face Much Higher Risk of Early Death

Posted 28 Oct 2015 by Drugs.com

WEDNESDAY, Oct. 28, 2015 – American adults with schizophrenia face a much higher risk of an early death, particularly from heart and lung diseases associated with smoking, a new study finds. The rise in risk "is evident in early adulthood and persists into later life. Especially high risks of mortality were observed from diseases for which tobacco use is a key risk factor," concluded a team led by Dr. Mark Olfson, of Columbia University in New York City. The issue is a familiar one, said one expert who reviewed the new findings. "Individuals with mental illnesses like schizophrenia and bipolar disorder die, on average, approximately two decades early, and primarily from cardiovascular disease and other preventable chronic illnesses," said Dr. Michael Compton, chair of psychiatry at Lenox Hill Hospital in New York City. In the study, Olfson's team looked at data from more than 1 million ... Read more

Related support groups: Diabetes, Type 2, Cancer, Chronic Obstructive Pulmonary Disease, Schizophrenia, Pneumonia

Brain Inflammation May Be Linked to Schizophrenia

Posted 16 Oct 2015 by Drugs.com

FRIDAY, Oct. 15, 2015 – Researchers say they've found a link between brain inflammation and schizophrenia. British investigators used PET scans to assess immune cell activity in the brains of 56 people. Some had schizophrenia, some were at risk for the mental disorder, and others had no symptoms or risk of the disease. The results showed that immune cells are more active in the brains of people with schizophrenia and those at risk for the disease. "Our findings are particularly exciting because it was previously unknown whether these cells become active before or after onset of the disease," lead author Peter Bloomfield, of the Medical Research Council's Clinical Sciences Center at Imperial College London, said in a college news release. "Now we have shown this early involvement, mechanisms of the disease and new medications can hopefully be uncovered," he added. The findings could ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Risperdal, Latuda, Zyprexa, Risperidone, Schizoaffective Disorder, Geodon, Saphris, Seroquel XR, Oppositional Defiant Disorder, Quetiapine, Psychosis, Agitation, Olanzapine, Haldol, Agitated State, Invega

FDA Approves Aristada (aripiprazole lauroxil) for Schizophrenia

Posted 6 Oct 2015 by Drugs.com

October 6, 2015 – On October 5, the U.S. Food and Drug Administration approved Aristada (aripiprazole lauroxil) extended release injection to treat adults with schizophrenia. Aristada is administered by a health care professional every four to six weeks using an injection in the arm or buttocks. Schizophrenia is a chronic, severe and disabling brain disorder affecting about one percent of Americans. Typically, symptoms are first seen in adults younger than 30 years of age and include hearing voices, believing other people are reading their minds or controlling their thoughts, and being suspicious or withdrawn. “Long-acting medications to treat schizophrenia can improve the lives of patients,” said Mitchell Mathis, M.D., director of the Division of Psychiatry Products in the FDA’s Center for Drug Evaluation and Research. “Having a variety of treatment options and dosage forms availab ... Read more

Related support groups: Schizophrenia, Aripiprazole, Aristada

ERs Often 'Safety Net' Care for People With Schizophrenia: CDC

Posted 23 Sep 2015 by Drugs.com

WEDNESDAY, Sept. 23, 2015 – A new report finds that, too often, under-medicated Americans suffering from schizophrenia end up seeking care in the nation's hospital emergency rooms. The report, issued Wednesday by the U.S. Centers for Disease Control and Prevention, found that between 2009 and 2011, over 382,000 visits to ERs were recorded for people aged 18 to 64 with schizophrenia. Many of these cases involved people on Medicaid who were either homeless or living in places such as nursing homes or group homes, the researchers said. Emergency departments "may serve as a safety net for schizophrenic patients not otherwise receiving care," said Dr. Michael Albert and Linda McCaig, both of whom work at the CDC's National Center for Health Statistics (NCHS). Mental health expert Dr. Michael Birnbaum said the new findings were "not surprising." "Unfortunately many people with mental illness ... Read more

Related support groups: Seroquel, Abilify, Lithium, Schizophrenia, Risperdal, Latuda, Zyprexa, Risperidone, Schizoaffective Disorder, Geodon, Saphris, Seroquel XR, Quetiapine, Psychosis, Olanzapine, Haldol, Invega, Clozapine, Haloperidol, Compazine

Vraylar Approved for Schizophrenia, Bipolar Disorder

Posted 22 Sep 2015 by Drugs.com

FRIDAY, Sept. 18, 2015 – Vraylar (cariprazine) has been approved by the U.S. Food and Drug Administration to treat two forms of mental illness among adults, schizophrenia and bipolar disorder. Schizophrenia is a chronic, severe disorder affecting some 1 percent of people in the United States. Symptoms, which typically begin in adults under age 30, commonly include hearing voices or seeing images that aren't real. Warning signs also may include believing other people are reading their minds or controlling their thoughts, suspicion and withdrawal, the agency said in a news release. Bipolar disorder, sometimes called manic-depression, commonly includes symptoms such as alternating periods of depression and mania, or "highs," characterized by irritability, restlessness, talking quickly, impulsive behavior and decreased need for sleep, the FDA said. The drug – a capsule taken once a day – ... Read more

Related support groups: Bipolar Disorder, Schizophrenia, Vraylar, Cariprazine

Drug May Calm Agitation in Alzheimer's Patients

Posted 22 Sep 2015 by Drugs.com

TUESDAY, Sept. 22, 2015 – A drug that combines a cough suppressant with a heart medication might offer a safer option for calming the agitation that commonly affects people with Alzheimer's disease, an early clinical trial suggests. The study, of 220 Alzheimer's patients, found that the drug – called Nuedexta – generally eased agitation symptoms over 10 weeks. And it did not worsen patients' problems with memory, thinking and judgment, researchers reported in the Sept. 22/29 issue of the Journal of the American Medical Association. As Alzheimer's disease progresses, people often go through periods of agitation that can range from restlessness and pacing to aggressive behavior like yelling, fighting and destroying objects. If those issues can be managed without medication, that's always best, said Dr. Sam Gandy, a professor of neurology and psychiatry at Mount Sinai Hospital, in New ... Read more

Related support groups: Bipolar Disorder, Seroquel, Abilify, Schizophrenia, Risperdal, Latuda, Zyprexa, Risperidone, Schizoaffective Disorder, Geodon, Saphris, Seroquel XR, Quetiapine, Alzheimer's Disease, Agitation, Olanzapine, Agitated State, Invega, Clozapine, Aripiprazole

FDA Approves Vraylar (cariprazine) for Schizophrenia and Bipolar Disorder

Posted 20 Sep 2015 by Drugs.com

September 17, 2015 – The U.S. Food and Drug Administration today approved Vraylar (cariprazine) capsules to treat schizophrenia and bipolar disorder in adults. “Schizophrenia and bipolar disorder can be disabling and can greatly interfere with day-to-day activities,” said Mitchell Mathis, M.D., director of the Division of Psychiatry Products in the FDA’s Center for Drug Evaluation and Research. “It is important to have a variety of treatment options available to patients with mental illnesses so that treatment plans can be tailored to meet a patient’s individual needs.” Schizophrenia is a chronic, severe and disabling brain disorder affecting about one percent of Americans. Typically, symptoms are first seen in adults younger than 30 years of age and include hearing voices or seeing things that are not there, believing other people are reading their minds or controlling their thoughts ... Read more

Related support groups: Bipolar Disorder, Schizophrenia, Vraylar, Cariprazine

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