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Combination Treatment May Help Depressed Alcoholics

Posted 15 Mar 2010 by Drugs.com

MONDAY, March 15 – Combined treatment with the antidepressant Zoloft (sertraline) and the alcoholism drug naltrexone improves the likelihood that people with both major depression and alcohol dependence will be able to stop drinking, U.S. researchers report. Their 14-week study of 170 patients found that 54 percent of those who received the combined treatment were able to stop drinking, compared with 21 to 28 percent for patients who received a placebo, Zoloft only, or naltrexone only. The patients who received the combined treatment also went for a longer period of time before they started drinking again – 61 days compared with 15 days for patients in the other groups. The findings may prove an important advance in the treatment of patients with alcohol dependence and depression, said the University of Pennsylvania researchers. "When depression and alcohol dependence occur together, ... Read more

Related support groups: Zoloft, Naltrexone, Alcohol Dependence, Alcoholism, Vivitrol, Revia

Addiction Meds May Help Gamblers

Posted 10 Dec 2009 by Drugs.com

THURSDAY, Dec. 10 – Drugs used to treat substance addictions could prove effective in treating pathological gambling, U.S. researchers say. They tested medications designed to decrease urges and increase inhibitions in two groups of male and female pathological gamblers: those driven by urge (they gamble when the desire becomes too strong to control) and those who don't have normal inhibition of impulsive behaviors (they're unable to control the desire to gamble even when the urges are minimal or nonexistent). The first group – those driven by urge – responded well to medications that block the brain opioid system (such as naltrexone) or certain receptors for the neurotransmitter glutamate (such as memantine). Gamblers with a family history of the problem responded especially well to the opioid blocker, the study found. The second group – those unable to control any impulse to ... Read more

Related support groups: Naltrexone, Namenda, Vivitrol, Revia, Memantine

Addiction Drug May Help Ease Fibromyalgia

Posted 17 Apr 2009 by Drugs.com

FRIDAY, April 17 – Low doses of an inexpensive drug called naltrexone – already used for years to treat drug addiction – helped reduce pain and fatigue in women with the painful disorder fibromyalgia, a new study has found. "Physicians have been using this off-label for a while," said study co-author Jarred Younger, an instructor in anesthesia and pain medicine at Stanford University School of Medicine. The findings were published online April 17 in the journal Pain Medicine. Fibromyalgia is a chronic ailment, marked by musculoskeletal pain and sensitivity to being touched. Some experts say it may affect up to 4 percent of the population. Three prescription drugs are also on the market to treat fibromyalgia, Younger said. But, he added, "the three drugs don't solve the problem for everyone. Some don't respond to any of these drugs." Younger said he got the idea to study naltrexone ... Read more

Related support groups: Fibromyalgia, Revia

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Opiate Dependence, Alcohol Dependence, Trichotillomania, Fibromyalgia