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Renal Cell Carcinoma News (Page 2)

Related terms: Adenocarcinoma of renal cells, Cancer, Hypernephroma, Cancer, Kidney, Cancer, Renal, Cancer, Renal Cell Carcinoma, Hypernephroma, Kidney Cancer, Renal Cancer

Novel Drugs Show Early Promise Against Several Cancers

Posted 4 Jun 2012 by Drugs.com

SATURDAY, June 2 – Two related "immunotherapy" drugs show early evidence of being able to thwart a variety of tough-to-treat, advanced cancers. About one-quarter of patients with advanced melanoma, kidney or lung cancer saw their tumors shrink when taking one of the two drugs, researchers reported Saturday. But the findings are extremely preliminary. Phase 1 studies such as this aren't designed to look at tumor shrinkage at all, but simply to establish dosage. And the therapies produced some serious side effects. While seeing results in a study such as this is "exciting," said Dr. Len Lichtenfeld, deputy chief medical officer at the American Cancer Society, "this was not the focus of the study." The two experimental drugs are antibodies that target two proteins in a key pathway of the immune system. "Cancers seem to have co-opted this pathway to enable them to fly below the radar of ... Read more

Related support groups: Cancer, Lung Cancer, Renal Cell Carcinoma, Melanoma, Skin Cancer

Kidney Cancer Patients Fare Better With Tumor Removal Only

Posted 17 Apr 2012 by Drugs.com

TUESDAY, April 17 – Kidney cancer patients who have only the tumor removed, not the entire kidney, have higher survival rates, a new study finds. The research involved more than 7,000 Medicare patients with early-stage kidney cancer who underwent surgery to remove either the entire organ (radical nephrectomy) or only the tumor and a small margin of healthy tissue around it (partial nephrectomy). After an average follow-up of five years, 25 percent of patients who had a partial nephrectomy had died, compared with 42 percent of those who had a radical nephrectomy, researchers at the University of Michigan Comprehensive Cancer Center reported. The study appears in the April 18 issue of the Journal of the American Medical Association. "For patients who are candidates for partial nephrectomy, it should be the preferred treatment option. We found that patients who were younger or had ... Read more

Related support groups: Renal Cell Carcinoma

Immune-Based Drug Combo Might Extend Cancer Survival

Posted 2 Apr 2012 by Drugs.com

MONDAY, April 2 – Cancer patients who receive a combination of low-dose interleukin-2 and retinoic acid after conventional therapy seem to live longer than those who don't get the combination. These new study findings, slated for presentation this week at the annual meeting of the American Association for Cancer Research in Chicago, were seen across individuals with many different forms of advanced malignancies, including breast, lung and colon cancers. Retinoic acid is derived from vitamin A. Interleukin-2, a compound that fortifies the immune system, is approved at high doses to treat "metastatic" melanoma and kidney cancer. Metastatic means that a cancer has spread. The study showed that "these biological compounds may work at low doses. Bigger doses are not always better," said lead author Dr. Francesco Recchia, director of the oncology department at Civilian Hospital in Avezzano, ... Read more

Related support groups: Cancer, Breast Cancer, Lung Cancer, Colorectal Cancer, Renal Cell Carcinoma, Non-Small Cell Lung Cancer, Melanoma, Pancreatic Cancer, Ovarian Cancer, Small Cell Lung Cancer, Melanoma - Metastatic, Gastric Cancer

Inlyta Approved for Advanced Kidney Cancer

Posted 30 Jan 2012 by Drugs.com

FRIDAY, Jan. 27 – Inlyta (axitinib) has been approved by the U.S. Food and Drug Administration to treat advanced renal cell carcinoma in people who haven't responded to another drug. Renal cell carcinoma is a form of kidney cancer that begins in tissue that lines the kidney's small tubes. Inlyta blocks proteins that help fuel tumor growth in this area, the FDA said in a news release. Six medications had been sanctioned previously for advanced kidney cancer, the agency said. In a study of 723 people with the advanced form of kidney cancer, the most common side effects of Inlyta included diarrhea, high blood pressure, fatigue, loss of appetite, nausea, loss of voice, weight loss, weakness and constipation. Among some patients, Inlyta also caused significant bleeding, which in some cases proved fatal. The FDA also warned that people with high blood pressure should make sure the problem is ... Read more

Related support groups: Renal Cell Carcinoma

FDA Approves Inlyta for Advanced Renal Cell Carcinoma

Posted 27 Jan 2012 by Drugs.com

FRIDAY, January 27, 2012 – The U.S. Food and Drug Administration today approved Inlyta (axitinib) to treat patients with advanced kidney cancer (renal cell carcinoma) who have not responded to another drug for this type of cancer. Renal cell carcinoma is a type of kidney cancer that starts in the lining of very small tubes in the kidney. Inlyta works by blocking certain proteins called kinases that play a role in tumor growth and cancer progression. Inlyta is a pill that patients take twice a day. “This is the seventh drug that has been approved for the treatment of metastatic or advanced kidney cell cancer since 2005,” said Richard Pazdur, M.D., director of the Office of Hematology and Oncology Products in the FDA’s Center for Drug Evaluation and Research. “Collectively, this unprecedented level of drug development within this time period has significantly altered the treatment parad ... Read more

Related support groups: Renal Cell Carcinoma

Cancer Patients Should Ask Doctors to Use Simple Terms

Posted 28 Sep 2011 by Drugs.com

WEDNESDAY, Sept. 28 – Cancer patients are often faced with many difficult-to-understand treatment choices that can have serious side effects and even mean the difference between life and death. That's why it's crucial that patients insist doctors use plain language in explaining the options, advised Angela Fagerlin, an associate professor of internal medicine at the University of Michigan Medical School and a researcher at the U-M Comprehensive Cancer Center. "People are making life and death decisions that may affect their survival and they need to know what they're getting themselves into. Cancer treatments and tests can be serious. Patients need to know what kind of side effects they might experience as a result of the treatment they undergo," Fagerlin said in a university news release. She and her colleagues outlined a number of tips to help patients get the information they need ... Read more

Related support groups: Cancer, Provera, Depo-Provera, Methotrexate, Breast Cancer, Accutane, Lupron, Prostate Cancer, Tamoxifen, Medroxyprogesterone, Arimidex, Femara, Tretinoin, Lupron Depot, Gleevec, Fluorouracil, Lung Cancer, Rituxan, Colorectal Cancer, Renal Cell Carcinoma

NSAID Painkillers Linked to Risk of Kidney Cancer

Posted 12 Sep 2011 by Drugs.com

MONDAY, Sept. 12 – The long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as Advil, Motrin and Aleve may slightly increase the risk for developing kidney cancer, Harvard researchers report. Millions of people use these drugs regularly for pain and they have been associated with reducing the risk of some cancers, the researchers added. "NSAIDs have been associated with a reduced risk of several types of cancer, including colorectal, breast and prostate," said lead researcher Eunyoung Cho, an assistant professor of medicine at Brigham and Women's Hospital and Harvard Medical School. "Our study raises a contradicting possibility that non-aspirin NSAIDs may elevate the risk of certain types of cancer." "If our studies are confirmed, risks and benefits should be considered in deciding whether to use analgesics, especially for long duration," she added. The report was ... Read more

Related support groups: Ibuprofen, Naproxen, Meloxicam, Diclofenac, Advil, Voltaren, Aleve, Mobic, Motrin, Indomethacin, Renal Cell Carcinoma, Etodolac, Toradol, Nabumetone, Flector, Naprosyn, Arthrotec, Relafen, Ketorolac, Ketoprofen

Agent Orange Linked to Kidney Cancer: Study

Posted 15 May 2011 by Drugs.com

SATURDAY, May 14 – There appears to be a link between Agent Orange and kidney cancer in U.S. veterans exposed to the herbicide in Vietnam, a new study suggests. Researchers at the Veterans Affairs Medical Center in Shreveport, La. examined the records of 297 patients diagnosed with kidney cancer between 1987 and 2009. Thirteen of the patients, aged 39 to 63 when they were diagnosed, said they had been exposed to Agent Orange. Documented exposure to the herbicide and pathology reports were available for 10 of the patients. The researchers reviewed these patients' age at diagnosis, tumor size, side of lesion, pathology and survival. Nine of the 10 patients had clear-cell cancers, which typically have worse outcomes than papillary tumors, which appeared in one patient. One patient had both clear-cell and papillary cancers. During the average follow-up of 54 months, four patients developed ... Read more

Related support groups: Renal Cell Carcinoma

Fewer Cancer Patients May Be Depressed Than Thought

Posted 20 Jan 2011 by Drugs.com

THURSDAY, Jan. 20 – The rate of depression among cancer patients may be lower than previously believed, a new study indicates. An international team of researchers analyzed 94 studies involving more than 14,000 patients and found that about one-sixth of cancer patients suffer depression and about one-third have a more widely defined mood disorder. Only modest rates of depression and anxiety occurred in cancer patients in the first five years after diagnosis, which suggests that depression is not inevitable in these patients, the researchers said. Only when it was combined with other mood disorders was depression common, occurring in 30 percent of hospitalized cancer patients. The study is published online Jan. 19 in The Lancet Oncology. Rates of depression and anxiety were not significantly different between patients receiving palliative care (care designed to ease pain and increase ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Renal Cell Carcinoma, Basal Cell Carcinoma, Brain Tumor, Breast Cancer, Metastatic, Non-Small Cell Lung Cancer, Melanoma, Skin Cancer, Pancreatic Cancer, Ovarian Cancer, Endometrial Cancer, Osteosarcoma, Cervical Cancer, Breast Cancer - Adjuvant, Small Cell Lung Cancer, Melanoma - Metastatic

1 in 5 Cancer Survivors Suffers Chronic Pain, Study Finds

Posted 20 Jan 2011 by Drugs.com

WEDNESDAY, Jan. 19 – More than 40 percent of cancer survivors experience pain, and the risk is highest among black and female patients, finds a new study. Researchers at the University of Michigan Health System surveyed nearly 200 U.S. cancer survivors and found that 43 percent had experienced pain since their diagnosis, and 20 percent suffered chronic cancer-related pain at least two years later. Among white patients, the most significant source of pain was cancer surgery (53.8 percent), and among black patients the greatest source of pain was cancer treatment (46.2 percent), according to the report. In addition, the study found that compared to men, women had more pain, more pain flare-ups, more disability due to pain and were more depressed because of pain. The authors also noted that black patients were more likely to report greater severity of pain and more pain-related ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Renal Cell Carcinoma, Basal Cell Carcinoma, Brain Tumor, Breast Cancer, Metastatic, Non-Small Cell Lung Cancer, Melanoma, Skin Cancer, Pancreatic Cancer, Ovarian Cancer, Endometrial Cancer, Osteosarcoma, Breast Cancer - Adjuvant, Cervical Cancer, Small Cell Lung Cancer, Stomach Cancer

Demand for Radiation Therapy Predicted to Exceed Supply

Posted 21 Oct 2010 by Drugs.com

THURSDAY, Oct. 21 – Over the next decade, the growth in demand for radiation therapy in the United States will be 10 times greater than the increase in new radiation oncologists, a difference that could affect cancer patients' access to treatment, according to a new study. Between 2010 and 2020, the number of patients requiring radiation therapy will increase 22 percent but the number of full-time radiation oncologists entering the workforce will increase just 2 percent, said researchers at the University of Texas M.D. Anderson Cancer Center in Houston and colleagues. They based their predictions on projections that this year 3,943 radiation oncologists will treat an estimated 470,000 patients in the United States. The large increase in demand for radiation therapy will be partly due to growing numbers of older adults and minorities, groups in which certain types of cancers are more ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Renal Cell Carcinoma, Basal Cell Carcinoma, Brain Tumor, Breast Cancer, Metastatic, Non-Small Cell Lung Cancer, Melanoma, Skin Cancer, Pancreatic Cancer, Ovarian Cancer, Endometrial Cancer, Osteosarcoma, Breast Cancer - Adjuvant, Cervical Cancer, Small Cell Lung Cancer, Stomach Cancer

Cancer Patients' Secondary Symptoms Need Attention: Study

Posted 11 Oct 2010 by Drugs.com

MONDAY, Oct. 11 – Many cancer patients with pain or depression also experience physical symptoms, such as fatigue, dry mouth and nausea, that can cause disability, a new study shows. Doctors need to recognize and treat these symptoms in order to improve quality of life for cancer patients, said Dr. Kurt Kroenke, of the Richard Roudebush VA Medical Center, Indiana University, and Regenstrief Institute Inc. in Indianapolis, and colleagues. They analyzed data from 405 cancer patients who had either pain or depression and found that all the patients had at least one of 22 physical symptoms examined in the study. More than half of patients reported 15 of the 22 symptoms. The most common symptoms were fatigue (97.5 percent), difficulty sleeping (about 79 percent), pain in limbs or joints (78 percent), back pain (nearly 75 percent) and memory problems (72 percent). The patients also reported ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Renal Cell Carcinoma, Basal Cell Carcinoma, Brain Tumor, Breast Cancer, Metastatic, Non-Small Cell Lung Cancer, Melanoma, Skin Cancer, Pancreatic Cancer, Ovarian Cancer, Endometrial Cancer, Osteosarcoma, Breast Cancer - Adjuvant, Cervical Cancer, Small Cell Lung Cancer, Stomach Cancer

Many Docs Deliver Cancer Diagnosis Badly: Study

Posted 7 Jul 2010 by Drugs.com

WEDNESDAY, July 7 – One patient found out he had cancer by reading his radiology report. Another got the news when her neurologist called to say he had arranged for her to see a neurosurgeon. When she asked why, the doctor told her she had a brain tumor and hung up. A third learned she had breast cancer listening to her answering machine with her grandson sitting on her lap. A new study about how people learn of cancer diagnoses finds that many doctors have poor communication skills and often leave patients stranded with devastating information about a deadly illness, sometimes in a public setting. One-third of the cancer patients in the U.S. National Cancer Institute study recalled being told on the phone, in an emergency room, radiology department or other public hospital setting that they had cancer, most often leukemia, lymphoma or brain tumors. "It's really dismaying to think that ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Renal Cell Carcinoma, Basal Cell Carcinoma, Brain Tumor, Breast Cancer, Metastatic, Non-Small Cell Lung Cancer, Melanoma, Skin Cancer, Pancreatic Cancer, Ovarian Cancer, Endometrial Cancer, Osteosarcoma, Cervical Cancer, Breast Cancer - Adjuvant, Small Cell Lung Cancer, Bladder Cancer

Cost-Conscious Cancer Survivors Skip Care

Posted 14 Jun 2010 by Drugs.com

MONDAY, June 14 – Millions of Americans with a history of cancer, particularly people under age 65, are delaying or skimping on medical care because of worries about the cost of treatment, a new study suggests. The finding raises troubling questions about the long-term survival and quality of life of the 12 million adults in the United States whose lives have been forever changed by a diagnosis of cancer. "I think it's concerning because we recognize that cancer survivors have many medical needs that persist for years after their diagnosis and treatment," said study lead author Kathryn E. Weaver, an assistant professor in the Department of Social Sciences & Health Policy at Wake Forest University Baptist Medical Center in Winston-Salem, N.C. The report was published online June 14 in Cancer, a journal of the American Cancer Society. Cost concerns have posed a threat to cancer ... Read more

Related support groups: Cancer, Breast Cancer, Prostate Cancer, Lung Cancer, Colorectal Cancer, Renal Cell Carcinoma, Basal Cell Carcinoma, Brain Tumor, Breast Cancer, Metastatic, Non-Small Cell Lung Cancer, Melanoma, Skin Cancer, Pancreatic Cancer, Ovarian Cancer, Endometrial Cancer, Osteosarcoma, Breast Cancer - Adjuvant, Cervical Cancer, Small Cell Lung Cancer, Stomach Cancer

Kidney Removal May Be Ill-Advised for Some Elderly

Posted 10 May 2010 by Drugs.com

MONDAY, May 10 – Removing a kidney does not seem to extend the life of elderly people with kidney cancer that has not spread, a new study finds. Instead, it suggests, people with such cancer should undergo more conservative treatments that preserve the non-cancerous parts of their kidneys. Kidney cancer cases have increased over the past 10 years, especially among older people, and doctors are trying to figure out the best way to treat what they call localized cancer in this age group. In the new study, Dr. Steve Campbell of the Cleveland Clinic and his colleagues examined the medical records of 537 people who were at least 75 years old and had localized kidney tumors. About 20 percent of them were simply observed, 53 percent had surgery that spared their kidney and 27 percent had their kidney removed. In the next four years, 28 percent of the overall group died, but just 4 percent of ... Read more

Related support groups: Renal Cell Carcinoma

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