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Statins May Help Prevent Enlarged Prostate: Study

Posted 21 May 2012 by Drugs.com

MONDAY, May 21 – Statin drugs commonly used to lower cholesterol levels may also slow the unhealthy growth of the prostate in men with elevated blood levels of prostate-specific antigen, a new study finds. Prostate-specific antigen, or PSA, levels are often elevated due to cancer or other conditions involving the prostate, explained researchers from Duke University Medical Center in Durham, N.C. The study authors noted that their findings are significant because an enlarged prostate affects up to 90 percent of men older than 70 years and can lead to bladder or kidney damage. Many of these men may already be taking a statin, which include cholesterol-lowering drugs such as Crestor, Lipitor, Pravachol or Zocor. "Given that prostate enlargement is an important health problem in the United States and elsewhere, and will be a larger problem as the population ages, it's important to ... Read more

Related support groups: Lipitor, Simvastatin, Benign Prostatic Hyperplasia (BPH), Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Benefits of Widespread Statin Use Outweigh Risks: Study

Posted 17 May 2012 by Drugs.com

THURSDAY, May 17 – Statins – commonly used cholesterol-lowering drugs – can significantly lower the risk for heart disease in people with no history of vascular disease, according to a new study. Researchers from the University of Oxford in England found the medication reduced the risk of major heart-related problems, such as hearts attacks and strokes, in men and women of all ages with heart disease – as well as those with no previous history of the condition – by about 20 percent. The benefits of widespread statin use outweigh any known side effects, said the study's authors, led by Colin Baigent, a professor in the clinical trial service unit and epidemiological studies unit at Oxford. The researchers said their findings should prompt a review of national and international guidelines on these drugs. Current U.S. and European guidelines restrict statin use to people with at least ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Statins May Help Prevent Irregular Heartbeat in Elderly

Posted 9 May 2012 by Drugs.com

WEDNESDAY, May 9 – The widely used class of cholesterol-lowering medications known as statins may help elderly patients with high blood pressure avoid developing atrial fibrillation, a heart rhythm abnormality tied to stroke. "Our study found that statin therapy in elderly patients with hypertension reduces the risk of new-onset atrial fibrillation," said Dr. Chen-Ying Hung, lead author of a study scheduled for presentation Wednesday at the Heart Rhythm Society's annual meeting in Boston. But the findings are extremely preliminary and don't provide enough evidence to support this particular use of statins, such as Lipitor (atorvastatin) and Zocor (simvastatin) just yet, said the study authors and outside experts alike. "We still need further studies to confirm this relationship before we can suggest statin use in [this population]," said Hung, a fellow at the Cardiovascular Center at ... Read more

Related support groups: Atrial Fibrillation, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Rate of Statin-Linked Muscle Woes Unclear, Study Suggests

Posted 27 Apr 2012 by Drugs.com

FRIDAY, April 27 – It's been long known that people on high doses of statins, cholesterol-lowering medications taken by millions of Americans, are at risk for a rare yet serious muscle condition. However, new research suggests that the frequency of the condition, called rhabdomyolysis, is a bit less clear due to confusion with the codes health professionals use to classify and report such problems. Statins include such bestselling drugs as Crestor, Lipitor, Pravachol and Zocor. Muscle ailments have long been cited as a rare but possible side effect of statin use, particularly at higher doses. In the new study, University of Washington researchers evaluated the use of the diagnostic code for "statin-related rhabdomyolysis," a serious condition involving achy muscles that is sometimes accompanied by kidney problems. The code was introduced in 2006 as a way of tracking how many cases of ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Rheumatoid Arthritis Patients Who Quit Statins May Face Raised Death Risk

Posted 28 Mar 2012 by Drugs.com

WEDNESDAY, March 28 – People suffering from rheumatoid arthritis who stop taking their cholesterol-lowering drugs may raise their risk of dying, a new study finds. In fact, those who stopped taking statins raised their chances of dying from cardiovascular disease by 60 percent and dying from any cause by 79 percent during the course of the study, the Canadian researchers reported. Since rheumatoid arthritis is associated with an increased risk of cardiovascular disease, patients often are prescribed statins such as Lipitor (atorvastatin) or Crestor (rosuvastatin) to lower their cholesterol. "Doctor knows best," said Dr. Richard Furie, chief of the division of rheumatology at North Shore-LIJ Health System in Lake Success, N.Y. "Whatever medicines your doctor puts you on, take them all." "We know that in inflammatory diseases such as rheumatoid arthritis, cardiovascular events are a ... Read more

Related support groups: Rheumatoid Arthritis, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Showing Patients Images of Their Clogged Arteries a Powerful Wake-Up Call

Posted 25 Mar 2012 by Drugs.com

SATURDAY, March 24 – Showing patients with clogged arteries evidence of their condition makes them more likely to stick with treatments such as weight loss and cholesterol-lowering statins, two related studies found. Coronary artery disease is the most common type of heart disease in Americans, but many patients fail to adhere to therapies that can treat or prevent heart disease. For example, patient compliance with statin therapy has been reported to be as low as 20 percent to 50 percent, the researchers said. The two studies included patients who underwent coronary artery calcium scoring with cardiac CT, a test that takes clear, detailed pictures of the heart. Patients with the most severe coronary artery disease who saw images of their heart were 2.5 times more likely to take statins as directed, and more than three times more likely to lose weight as those whose scans showed little ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Coronary Artery Disease (CAD), Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Statin Alternative Looks Promising in Early Trials

Posted 21 Mar 2012 by Drugs.com

WEDNESDAY, March 21 – A new anti-cholesterol drug appears safe and effective in people already taking statins such as Lipitor, making it a potential addition to statin therapy or an alternative, a preliminary new study suggests. Two single-dose trials in healthy volunteers and a multiple-dose trial in a group with high cholesterol showed that the drug, known as a monoclonal antibody, reduced low-density lipoprotein (LDL, or "bad") cholesterol levels an average of 40 percent. The injectable drug was also well-tolerated by all participants, with headache the most commonly reported side effect. The drug works by attacking a destructive enzyme in the liver, keeping LDL cholesterol from spilling into the bloodstream, according to the report published in the March 22 issue of the New England Journal of Medicine. "It was entirely safe, as best they could tell, and LDL levels plummeted within ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Could Statins Help Prevent Pneumonia?

Posted 19 Mar 2012 by Drugs.com

MONDAY, March 19 – Statin drugs, which are used to lower cholesterol, might reduce a bit the risk of developing pneumonia, a new study suggests. Researchers analyzed data from a large international study that looked at the efficacy of rosuvastatin (Crestor) in preventing heart disease. The trial included almost 18,000 adults aged 50 or older who had no history of heart disease or diabetes. Participants were randomly selected to receive Crestor or an inactive placebo. "These data from a major randomized trial support the hypothesis that statin treatment may be associated with a modest protective effect against some infections," said lead researcher Dr. Victor Novack, head of the Clinical Research Center at Soroka University Medical Center in Israel. "We consider this analysis to be an additional step toward a definite trial that will specifically investigate the statin effect on ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pneumonia, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Can Statins Prevent Parkinson's Disease?

Posted 12 Mar 2012 by Drugs.com

MONDAY, March 12 – People taking popular cholesterol-lowering drugs called statins may have a slightly lower risk than others of developing Parkinson's disease, new research suggests. This effect may be even more pronounced among people younger than 60, according to the study published in the March issue of Archives of Neurology. However, the risk reduction was modest and may have been due to chance, the authors said, noting that more research is warranted, especially because statins can cause adverse side effects. "There is no clear verdict," said Dr. Stuart Isaacson, director of the Parkinson's Disease and Movement Disorders Center of Boca Raton, who was not involved in the study. "Right now we don't have any good evidence that there is anything we can do to reduce the risk of developing Parkinson's disease, but research is ongoing," added Isaacson, also an associate professor of ... Read more

Related support groups: Lipitor, Simvastatin, Parkinson's Disease, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

FDA Medwatch Alert: Statins and HIV or Hepatitis C Drugs: Drug Safety Communication - Interaction Increases Risk of Muscle Injury

Posted 2 Mar 2012 by Drugs.com

ISSUE: FDA notified healthcare professionals  of updates to the prescribing information concerning interactions between  protease inhibitors and certain statin  drugs. Protease inhibitors and statins taken together may raise the blood levels of statins and increase the risk for muscle injury (myopathy). The most serious form of myopathy, called rhabdomyolysis, can damage the kidneys and lead to kidney failure, which can be fatal. BACKGROUND: Statins are a class of prescription drugs used together with diet and exercise to reduce blood levels of low-density lipoprotein (LDL) cholesterol (“bad cholesterol”). HIV protease inhibitors are a class of prescription anti-viral drugs used to treat HIV. HCV protease inhibitors are a class of prescription anti-viral drugs used to treat hepatitis C infection. RECOMMENDATION: Healthcare professionals should follow the recommendations in the  pr ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Incivek, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Victrelis, Norvir, Kaletra, Telaprevir, Boceprevir, Ritonavir, Lescol, Reyataz

FDA Medwatch Alert: Statin Drugs - Drug Safety Communication: Class Labeling Change

Posted 29 Feb 2012 by Drugs.com

ISSUE: FDA has approved important safety label changes for the class of cholesterol-lowering drugs known as statins. The changes include removal of routine monitoring of liver enzymes from drug labels. Information about the potential for generally non-serious and reversible cognitive side effects and reports of increased blood sugar and glycosylated hemoglobin (HbA1c) levels has been added to the statin labels. The lovastatin label has been extensively updated with new contraindications and dose limitations when it is taken with certain medicines that can increase the risk for muscle injury. Read the FDA Drug Safety Communication for more information.   BACKGROUND: Statins are a class of prescription drugs used together with diet and exercise to reduce blood levels of low-density lipoprotein (LDL) cholesterol (“bad cholesterol”). Marketed as single-ingredient products, including Lipitor ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Vytorin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Simcor, Lescol, Lescol XL, Advicor, Mevacor, Pitavastatin, Baycol, Fluvastatin

FDA Adds Safety Warnings to Statins

Posted 28 Feb 2012 by Drugs.com

TUESDAY, Feb. 28 – The popular cholesterol-lowering drugs called statins will now come with revised labels warning of a slight increased risk of elevated blood sugar levels, which could lead to type 2 diabetes, as well as a warning on rare cases of confusion and memory loss, U.S. drug regulators said Tuesday. But the U.S. Food and Drug Administration, which made the announcement, and health-care professionals all stressed that the heart-protective benefits of statins – which include drugs such as Crestor, Lipitor, Pravachol and Zocor – far outweigh the risks spelled out on the new labels. "We want health-care professionals and patients to have the most current information on the risks of statins, but also to assure them that these medications continue to provide an important health benefit of lowering cholesterol," Dr. Mary Parks, director of the FDA's Division of Metabolism and ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Vytorin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Simcor, Lescol, Lescol XL, Advicor, Mevacor, Pitavastatin, Baycol, Fluvastatin

It's 'Buyer Beware' When Getting Statins Off the Internet

Posted 2 Feb 2012 by Drugs.com

THURSDAY, Feb. 2 – Be wary of buying the cholesterol-lowering drugs known as statins on the Internet, British researchers say. Common statins such as Lipitor, Crestor or Zocor may not be the same as advertised and sites often don't include warnings about side effects or even require a prescription, the researchers noted. "A potential purchaser of statins in the U.K., where one can only legally receive them on a doctor's prescription, searching the web for product, is likely to encounter sites from a wide geographical base and of generally poor quality," said lead researcher David Brown, from the School of Pharmacy and Biomedical Sciences at the University of Portsmouth. "Potentially, customers who obtain statins in this way, without their doctor's prescription, may not be aware of potential side effects and may put themselves in harm's way," he added. The report was published Feb. 2 in ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Altoprev, Fluvastatin, Baycol, Pitavastatin, Cerivastatin, Altocor

Statins Equally Effective in Women and Men

Posted 30 Jan 2012 by Drugs.com

MONDAY, Jan. 30 – Cholesterol-lowering drugs known as statins are equally effective in men and women, a new study finds. For both males and females, these drugs lowered the risk of a heart attack by about 20 percent, the researchers say. Previously, some thought that statins, which include Lipitor, Lovastatin and Crestor, benefited women less than men. "Statin therapy should be used to treat all appropriate patients, regardless of gender," said lead researcher Dr. William Kostis, of the cardiology division at Massachusetts General Hospital in Boston. "Despite prior concerns in the literature, the benefits of statin therapy pertain to both women and men," he added. The report was published in the Jan. 30 online edition of the Journal of the American College of Cardiology. Cardiovascular disease remains the leading cause of death among women and men in the United States. Statins are ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Altoprev, Fluvastatin, Baycol, Pitavastatin, Cerivastatin, Altocor

Statins May Stave Off Liver Cancer in People With Hepatitis B

Posted 26 Jan 2012 by Drugs.com

THURSDAY, Jan. 26 – Popular cholesterol-lowering statins may also lower risk for liver cancer among people with hepatitis B, a new study shows. Hepatitis B, an inflammation of the liver due to the hepatitis B virus, is one of the main causes of liver cancer. This is not the first time that statins have shown promise in reducing risk for cancer. Other studies have hinted that these drugs may play a role in preventing certain types of cancer, including breast cancer. In the new study of more than 33,000 individuals with hepatitis B followed from 1997 to 2008, those who took a statin were less likely to develop liver cancer, when compared to participants who were not prescribed statins. What's more, the longer a person took statins, the greater the liver-cancer risk reduction. Study participants were prescribed the statins to treat high cholesterol levels. Overall, 1,021 people developed ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Hepatitis B, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

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