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Cholesterol Drugs Might Boost Kidney Cancer Survival

Posted 7 May 2013 by Drugs.com

TUESDAY, May 7 – Cholesterol-lowering statin drugs that are taken by millions of Americans might also improve survival from a type of kidney cancer called renal cell carcinoma, a new study suggests. Statins – drugs such as Crestor, Lipitor, Pravachol and Zocor – have anti-inflammatory and cell self-destruction properties, and previous research has shown that these drugs may lower the risk of developing some types of cancer. The new research, presented Tuesday at the annual meeting of the American Urological Association in San Diego, suggests that the drugs might fight kidney cancer. "Given that one in four Americans over 45 years of age take a statin and renal cell carcinoma occurs most often in men ages 50 to 70, it may be prudent to prospectively evaluate if statins protect against [cancer] progression," study author Dr. Scott Eggener, an associate professor of urologic oncology at ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Renal Cell Carcinoma, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

High-Dose Statins Linked to Acute Kidney Damage

Posted 20 Mar 2013 by Drugs.com

TUESDAY, March 19 – People who take high doses of popular cholesterol-lowering drugs called statins may be more likely to develop kidney problems, a new study suggests. Specifically, those participants who took higher doses of statins were 34 percent more likely to be hospitalized for acute kidney injury during the first 120 days of treatment, compared to their counterparts who were taking lower doses. This risk remained elevated two years after starting treatment. The findings appeared online March 19 in the journal BMJ. Statins are widely prescribed to lower blood cholesterol levels, and can be very effective. They do, however, confer their share of risks, most notably liver damage and muscle pain or weakness. Doctors currently recommend that people take a liver enzyme test before or shortly after they begin taking statins. The issue of kidney damage as seen in the current study, ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Altoprev, Fluvastatin, Baycol, Pitavastatin, Altocor, Cerivastatin

Niacin Won't Help, May Harm Heart Patients: Study

Posted 10 Mar 2013 by Drugs.com

SATURDAY, March 9 – Combining the vitamin niacin with a cholesterol-lowering statin drug appears to offer patients no benefit and may also increase side effects, a new study indicates. It's a disappointing result from the largest-ever study of niacin for heart patients, which involved almost 26,000 people. In the study, patients who added the B-vitamin to the statin drug Zocor saw no added benefit in terms of reductions in heart-related death, non-fatal heart attack, stroke, or the need for angioplasty or bypass surgeries. The study also found that people taking niacin had more incidents of bleeding and/or infections than those who were taking an inactive placebo, according to a team reporting Saturday at the annual meeting of the American College of Cardiology, in San Francisco. "We are disappointed that these results did not show benefits for our patients," study lead author Jane ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Niacin, Zocor, Niaspan, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Slo-Niacin, Niaspan ER, Lescol, Lescol XL, Mevacor, Pitavastatin, Altoprev

TV Ads for Statins May Drive Overtreatment

Posted 8 Mar 2013 by Drugs.com

FRIDAY, March 8 – Television ads for cholesterol-lowering statin drugs may lead to overdiagnosis of high cholesterol and overtreatment with the drugs, according to a new study. The research found that patients' visits with doctors to ask about statins advertised on TV often lead to prescriptions for the drugs. The ads tell viewers about the health risks of high cholesterol and encourage them to seek medical advice, tests and appropriate treatment. The researchers wanted to assess the effect of this direct-to-consumer advertising. The study was published online March 7 in the Journal of General Internal Medicine. It examined how often more than 106,000 American adults were exposed to such ads between 2001 and 2007. Researchers also looked at whether these adults reported being diagnosed with high cholesterol, whether they had taken a statin in the previous year and their risk factors ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Niacin-Statin Combo May Cause Side Effects for Heart Patients

Posted 26 Feb 2013 by Drugs.com

TUESDAY, Feb. 26 – Combining the vitamin niacin with a cholesterol-lowering statin drug appears to raise side effects in heart patients, a new study indicates. Muscle, skin and gastrointestinal problems were among the side effects that caused one-quarter of patients to stop treatment in a study looking at whether the use of niacin in combination with a statin might reduce heart disease risk. Niacin has long been used to boost levels of "good" HDL cholesterol and decrease levels of "bad" LDL cholesterol and triglycerides (fats) in the blood in people at risk for heart disease and stroke. However, niacin also causes a number of side effects, including flushing of the skin. A drug called laropiprant can reduce the incidence of flushing in people taking niacin. This new study included nearly 26,000 patients with narrowing of the arteries. They received either 2 grams of extended-release ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Niacin, Zocor, Niaspan, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Slo-Niacin, Niaspan ER, Lescol, Lescol XL, Mevacor, Altoprev

Lifestyle Affects Outcome of Peripheral Artery Procedure: Study

Posted 26 Dec 2012 by Drugs.com

WEDNESDAY, Dec. 26 – Patients with blocked leg arteries are less likely to suffer complications after a procedure to open their arteries if they quit smoking and take aspirin and cholesterol-lowering statins, a new study indicates. However, too few patients take such steps to relieve leg pain and cramping associated with peripheral artery disease, also known as PAD, according to the researchers. The new study of more than 1,300 patients found that only about 47 percent of them did not smoke and were taking aspirin and a statin – drugs that can reduce blood clots and improve blood flow – when they were admitted to hospital for a peripheral vascular intervention, such as angioplasty, which is performed to open blocked leg arteries and improve blood flow. When they were discharged from hospital, 71 percent of the patients were taking aspirin and a statin and either did not smoke or ... Read more

Related support groups: Aspirin, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Ecotrin, Pravachol, Peripheral Arterial Disease, Bayer Aspirin, Lescol, Lescol XL, Bufferin, Low Dose ASA, Mevacor

Statins Plus Exercise Best at Lowering Cholesterol, Study Finds

Posted 27 Nov 2012 by Drugs.com

TUESDAY, Nov. 27 – People who exercise along with taking statins to lower their high cholesterol levels can dramatically reduce their risk of dying, a large new study suggests. "The reduction in death is independent; whatever statins do is independent of what exercise does," said lead researcher Peter Kokkinos, a professor in the cardiology department at the Veterans Affairs Medical Center in Washington, D.C. "When you combine the two, you get even better results," he said. "If you are taking statins, your mortality is about 35 percent lower versus not taking statins, but if you exercise, your mortality level decreases as your fitness level increases to the point where you can reach a 70 percent reduction in mortality." Kokkinos is talking about regular moderate exercise – not vigorous workouts. "Thirty minutes a day of brisk walking – not a whole lot," he said. Statin drugs include ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Cardiovascular Risk Reduction, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol

Statins May Cut Risk of Death From Cancer, Study Suggests

Posted 7 Nov 2012 by Drugs.com

WEDNESDAY, Nov. 7 – A large study of Danish cancer patients suggests that people taking cholesterol-lowering medications known as statins have a lower risk of premature death from cancer. The research, published Nov. 7 in the New England Journal of Medicine, found that statin use at the time of cancer diagnosis reduced the risk of dying from cancer-related causes by up to 15 percent. "That doesn't sound like that much, but chemotherapy only offers about a 15 percent to 20 percent reduction in the risk of dying," said Dr. Stig Bojesen, an author of the study and staff specialist in the department of clinical biochemistry at Copenhagen University Hospital, in Herlev, Denmark. Previous studies of statins such as Lipitor and Crestor have not shown that the drugs significantly affect overall cancer risk. But some research has suggested that statins may have a role in treating particular ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Altoprev, Fluvastatin, Baycol, Pitavastatin, Altocor, Cerivastatin

New Drug May Help Those Who Can't Take Statins

Posted 5 Nov 2012 by Drugs.com

MONDAY, Nov. 5 – An experimental drug may help patients who can't tolerate statins lower their cholesterol, a new Australian study suggests. The 12-week, phase 2 clinical trial was conducted at 33 international sites and included adults who suffered muscle problems when taking statins, a class of cholesterol-lowering drugs that includes Crestor and Lipitor. They received injections of a placebo or different doses of AMG145, which is a human monoclonal antibody. Human monoclonal antibodies are naturally occurring human antibodies that are genetically altered in a laboratory, cloned in large numbers and introduced into the patient to target disease sites. The patients who received AMG145 had 41 percent to 63 percent reductions in "bad" (LDL) cholesterol and did not experience significant muscle-related side effects, said study leader Dr. David Sullivan, of the Royal Prince Alfred ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Cholesterol Levels Dropping in U.S. Adults, Mostly From Statin Use

Posted 17 Oct 2012 by Drugs.com

TUESDAY, Oct. 16 – When it comes to coronary artery disease in the United States, there's good news and bad news. The good news? Average levels of the worst forms of cholesterol are dropping among U.S. adults. The bad news? Americans are achieving those better numbers not so much by changing their diet or ramping up their exercise, but largely by taking statins: cholesterol-lowering medications. A comprehensive look at how Americans are faring in the battle against coronary artery disease shows that over about 22 years, total cholesterol and LDL (low-density lipoprotein cholesterol, often called "bad" cholesterol) have declined. But the percentage of adults taking anti-cholesterol medications has climbed as well. In addition to looking at the average levels of cholesterol and factors associated with increased risk of heart disease, the researchers noted whether participants were taking ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, High Cholesterol - Familial Heterozygous, Red Yeast Rice, Livalo, Pravachol, High Cholesterol - Familial Homozygous, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin

Statins Tied to Reduced Glaucoma Risk

Posted 2 Oct 2012 by Drugs.com

TUESDAY, Oct. 2 – Researchers may have discovered yet another potential use for the widely used cholesterol-lowering drugs known as statins. In a new study, older people with high cholesterol who had taken statins for two years had an 8 percent reduced risk of developing open-angle glaucoma, the most common form of the eye disease. "That's a big deal," said Dr. Mark Fromer, an ophthalmologist at Lenox Hill Hospital in New York City, and eye surgeon director for the New York Rangers hockey team. "We're talking 3 million people [in the United States] who have glaucoma and half those people don't know it." Fromer was not involved with the study, which appears in the October issue of Ophthalmology. Glaucoma, which often affects people over 60, can lead to blindness. People at higher risk include those with a family member with glaucoma, blacks and older Hispanics, according to the Glaucoma ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Glaucoma, Pravastatin, Atorvastatin, Zocor, Lovastatin, Glaucoma (Open Angle), Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Altoprev, Fluvastatin, Baycol, Pitavastatin

Statin Use Tied to Possible Boost in Cataract Risk

Posted 26 Aug 2012 by Drugs.com

FRIDAY, Aug. 24 – The millions of adults who currently use prescription statins to control their cholesterol levels may be inadvertently increasing their risk for developing age-related cataracts, new research suggests. The bump in cataract risk linked to statin use appears comparable to the elevated risk already known to exist among people with type 2 diabetes, the study team observed. That said, the study authors cautioned that more research is needed before being able to definitively say there is a cause-and-effect relationship between statins and cataract risk. "The bottom line is that there appears to be an increased risk among people taking statins as far as getting cataracts," said study lead author Elizabeth Irving, research chairwoman in the School of Optometry and Vision Science at the University of Waterloo in Ontario, Canada. "That was actually a surprise, because most of ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Cataract, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

Statins Won't Hurt, Might Even Help, Your Pancreas: Study

Posted 21 Aug 2012 by Drugs.com

TUESDAY, Aug. 21 – Statins don't raise the risk of pancreatitis, a painful and potentially life-threatening inflammation, a new review finds. Putting to rest concerns raised by previous research, this new study finds cholesterol-lowering drugs such as Lipitor (atorvastatin) and Zocor (simvastatin) may actually help ward off pancreatitis. The pooled analysis of 21 published and unpublished randomized, controlled trials – the gold standard of medical research – found that people taking statins were at 18 percent to 23 percent reduced chance of developing pancreatitis. Researchers also looked at a class of drugs called fibrates, which doctors prescribe for people with high triglycerides, another type of blood fat. Their analysis found a slight, but statistically insignificant, increase of developing pancreatitis from fibrates. "Statins seem to carry a previously unrecognized benefit of ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Lescol, Lescol XL, Mevacor, Altoprev, Fluvastatin, Baycol, Pitavastatin, Altocor, Cerivastatin

Statins' Heart Benefits Outweigh Diabetes Risk: Study

Posted 9 Aug 2012 by Drugs.com

THURSDAY, Aug. 9 – The cardiac benefits of statins outweigh any increased chances for developing diabetes, even among those who run the highest risk of developing the blood sugar disease, Harvard researchers report. The concern that these cholesterol-lowering drugs, which include the widely prescribed medications Lipitor, Crestor and Zocor, increased the risk for diabetes prompted the U.S. Food and Drug Administration to require labeling that warns users of the risk. "Earlier this year, concern was raised that patients taking statins had an increased risk of developing diabetes, and on that basis many patients stopped taking their medications," explained lead researcher Dr. Paul Ridker, director of the Center for Cardiovascular Disease Prevention at Brigham and Women's Hospital, in Boston. "Unfortunately, little if any data was available at that time to address not only the risks, but ... Read more

Related support groups: High Cholesterol, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Pravachol, Cardiovascular Risk Reduction, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol

Are Statins Less Helpful for Women?

Posted 25 Jun 2012 by Drugs.com

MONDAY, June 25 – The cholesterol-lowering drugs known as statins may be less effective for preventing death and recurrent strokes in women than in men, a new study suggests. A review of 11 trials found that statins such as Lipitor and Crestor prevent recurrent heart attacks in men and women, but it showed no benefit for women in terms of second stroke or death from all causes. However, experts who weren't involved with the study said it was flawed – women comprised only a fraction of participants, for example – and they contend the drugs are life-savers for both sexes. The report was published June 25 in the Archives of Internal Medicine. For the study, researchers led by Dr. Jose Gutierrez, of the vascular neurology program at the Neurological Institute of Columbia University Medical Center in New York City, pooled data on more than 43,000 participants from studies published prior ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Red Yeast Rice, Livalo, Ischemic Stroke - Prophylaxis, Pravachol, Lescol, Lescol XL, Mevacor, Fluvastatin, Altoprev, Pitavastatin, Baycol, Cerivastatin

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