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Can Statins Prevent Parkinson's Disease?

Posted 12 Mar 2012 by Drugs.com

MONDAY, March 12 – People taking popular cholesterol-lowering drugs called statins may have a slightly lower risk than others of developing Parkinson's disease, new research suggests. This effect may be even more pronounced among people younger than 60, according to the study published in the March issue of Archives of Neurology. However, the risk reduction was modest and may have been due to chance, the authors said, noting that more research is warranted, especially because statins can cause adverse side effects. "There is no clear verdict," said Dr. Stuart Isaacson, director of the Parkinson's Disease and Movement Disorders Center of Boca Raton, who was not involved in the study. "Right now we don't have any good evidence that there is anything we can do to reduce the risk of developing Parkinson's disease, but research is ongoing," added Isaacson, also an associate professor of ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Parkinson's Disease, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Baycol, Fluvastatin, Altoprev, Pitavastatin, Cerivastatin

FDA Medwatch Alert: Statins and HIV or Hepatitis C Drugs: Drug Safety Communication - Interaction Increases Risk of Muscle Injury

Posted 2 Mar 2012 by Drugs.com

ISSUE: FDA notified healthcare professionals  of updates to the prescribing information concerning interactions between  protease inhibitors and certain statin  drugs. Protease inhibitors and statins taken together may raise the blood levels of statins and increase the risk for muscle injury (myopathy). The most serious form of myopathy, called rhabdomyolysis, can damage the kidneys and lead to kidney failure, which can be fatal. BACKGROUND: Statins are a class of prescription drugs used together with diet and exercise to reduce blood levels of low-density lipoprotein (LDL) cholesterol (“bad cholesterol”). HIV protease inhibitors are a class of prescription anti-viral drugs used to treat HIV. HCV protease inhibitors are a class of prescription anti-viral drugs used to treat hepatitis C infection. RECOMMENDATION: Healthcare professionals should follow the recommendations in the  pr ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Incivek, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Victrelis, Kaletra, Telaprevir, Norvir, Lescol, Reyataz, Lexiva, Prezista

FDA Medwatch Alert: Statin Drugs - Drug Safety Communication: Class Labeling Change

Posted 29 Feb 2012 by Drugs.com

ISSUE: FDA has approved important safety label changes for the class of cholesterol-lowering drugs known as statins. The changes include removal of routine monitoring of liver enzymes from drug labels. Information about the potential for generally non-serious and reversible cognitive side effects and reports of increased blood sugar and glycosylated hemoglobin (HbA1c) levels has been added to the statin labels. The lovastatin label has been extensively updated with new contraindications and dose limitations when it is taken with certain medicines that can increase the risk for muscle injury. Read the FDA Drug Safety Communication for more information.   BACKGROUND: Statins are a class of prescription drugs used together with diet and exercise to reduce blood levels of low-density lipoprotein (LDL) cholesterol (“bad cholesterol”). Marketed as single-ingredient products, including Lipitor ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Vytorin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Simcor, Lescol, Lescol XL, Advicor, Mevacor, Altoprev, Pitavastatin, Baycol

FDA Adds Safety Warnings to Statins

Posted 28 Feb 2012 by Drugs.com

TUESDAY, Feb. 28 – The popular cholesterol-lowering drugs called statins will now come with revised labels warning of a slight increased risk of elevated blood sugar levels, which could lead to type 2 diabetes, as well as a warning on rare cases of confusion and memory loss, U.S. drug regulators said Tuesday. But the U.S. Food and Drug Administration, which made the announcement, and health-care professionals all stressed that the heart-protective benefits of statins – which include drugs such as Crestor, Lipitor, Pravachol and Zocor – far outweigh the risks spelled out on the new labels. "We want health-care professionals and patients to have the most current information on the risks of statins, but also to assure them that these medications continue to provide an important health benefit of lowering cholesterol," Dr. Mary Parks, director of the FDA's Division of Metabolism and ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Vytorin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Simcor, Lescol, Lescol XL, Advicor, Mevacor, Altoprev, Pitavastatin, Baycol

It's 'Buyer Beware' When Getting Statins Off the Internet

Posted 2 Feb 2012 by Drugs.com

THURSDAY, Feb. 2 – Be wary of buying the cholesterol-lowering drugs known as statins on the Internet, British researchers say. Common statins such as Lipitor, Crestor or Zocor may not be the same as advertised and sites often don't include warnings about side effects or even require a prescription, the researchers noted. "A potential purchaser of statins in the U.K., where one can only legally receive them on a doctor's prescription, searching the web for product, is likely to encounter sites from a wide geographical base and of generally poor quality," said lead researcher David Brown, from the School of Pharmacy and Biomedical Sciences at the University of Portsmouth. "Potentially, customers who obtain statins in this way, without their doctor's prescription, may not be aware of potential side effects and may put themselves in harm's way," he added. The report was published Feb. 2 in ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Pitavastatin, Baycol, Altoprev, Fluvastatin, Cerivastatin, Altocor

Statins Equally Effective in Women and Men

Posted 30 Jan 2012 by Drugs.com

MONDAY, Jan. 30 – Cholesterol-lowering drugs known as statins are equally effective in men and women, a new study finds. For both males and females, these drugs lowered the risk of a heart attack by about 20 percent, the researchers say. Previously, some thought that statins, which include Lipitor, Lovastatin and Crestor, benefited women less than men. "Statin therapy should be used to treat all appropriate patients, regardless of gender," said lead researcher Dr. William Kostis, of the cardiology division at Massachusetts General Hospital in Boston. "Despite prior concerns in the literature, the benefits of statin therapy pertain to both women and men," he added. The report was published in the Jan. 30 online edition of the Journal of the American College of Cardiology. Cardiovascular disease remains the leading cause of death among women and men in the United States. Statins are ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Pitavastatin, Baycol, Altoprev, Fluvastatin, Cerivastatin, Altocor

Statins May Stave Off Liver Cancer in People With Hepatitis B

Posted 26 Jan 2012 by Drugs.com

THURSDAY, Jan. 26 – Popular cholesterol-lowering statins may also lower risk for liver cancer among people with hepatitis B, a new study shows. Hepatitis B, an inflammation of the liver due to the hepatitis B virus, is one of the main causes of liver cancer. This is not the first time that statins have shown promise in reducing risk for cancer. Other studies have hinted that these drugs may play a role in preventing certain types of cancer, including breast cancer. In the new study of more than 33,000 individuals with hepatitis B followed from 1997 to 2008, those who took a statin were less likely to develop liver cancer, when compared to participants who were not prescribed statins. What's more, the longer a person took statins, the greater the liver-cancer risk reduction. Study participants were prescribed the statins to treat high cholesterol levels. Overall, 1,021 people developed ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Hepatitis B, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Baycol, Fluvastatin, Altoprev, Pitavastatin, Cerivastatin

Study Hints That Statins Might Fight Breast Cancer

Posted 19 Jan 2012 by Drugs.com

THURSDAY, Jan. 19 – Amid hints that statins – cholesterol-lowering drugs – might also play a role in preventing or treating certain types of cancer, new research sheds some light on how these drugs may help stop breast cancer in its tracks among certain women. The p53 tumor suppressor gene stops the uncontrolled growth of cancer cells, but some women with breast cancer have mutant forms of this gene. In the new study, when the mutant p53 cells were treated in the laboratory with statins, the cells stopped their erratic growth, and even died in some cases. It seems that the mutated p53 genes may activate the same pathway that the statins inhibit – the mevalonate pathway, the study suggests. The mevalonate pathway is important in the body's production of cholesterol. In the study, the effects of the statin drugs were erased when the mevalonate pathway was reactivated, supporting the ... Read more

Related support groups: Breast Cancer, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Baycol, Fluvastatin, Altoprev, Pitavastatin, Cerivastatin

Statins Cost Four Times More in U.S. Than in U.K.

Posted 13 Jan 2012 by Drugs.com

FRIDAY, Jan. 13 – Widely used cholesterol-lowering statin drugs cost about 400 percent more in the United States than in the United Kingdom, a new study shows. Prescription drug costs are a major issue in the ongoing debate about health costs in both the United States and the U.K., noted the researchers at the Boston University School of Medicine Boston Collaborative Drug Surveillance Program. For this study, they compared 2005 data from 280,000 people aged 55 to 64 in both countries and found that statins were prescribed to nearly 33 percent of those in the United States and more than 25 percent of those in the U.K. In the United States, the estimated annual cost of statins ranged from a high of $1,428 for simvastatin to a low of $314 for lovastatin. The annual cost of statins in the U.K. varied from a high of $500 for atorvastatin to a low of $164 for simvastatin. The total estimated ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Pitavastatin, Baycol, Altoprev, Fluvastatin, Cerivastatin, Altocor

Statins May Boost Diabetes Risk in Older Women

Posted 9 Jan 2012 by Drugs.com

MONDAY, Jan. 9 – Statin medications used by women after menopause appear to increase their risk of developing diabetes, according to a large, new study. The research echoes findings of other studies linking the cholesterol-lowering drugs with an increased diabetes risk in men and women. Statins include drugs such as Lipitor, Lescol and Mevacor. "We found statins increased the risk of diabetes about 48 percent after adjusting for different risk factors such as family history of diabetes, body mass index and [physical] activity," said Dr. Yunsheng Ma, associate professor of medicine and an epidemiologist at the University of Massachusetts Medical School in Worcester, Mass. "It's a moderate risk," he said. However, the study found an association, not a cause and effect. The authors stressed that the findings – published online Jan. 9 in the Archives of Internal Medicine – are not a ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Pitavastatin, Baycol, Altoprev, Fluvastatin, Cerivastatin, Altocor

Poor Lifestyles Harming U.S. Heart Health: Report

Posted 15 Dec 2011 by Drugs.com

THURSDAY, Dec. 15 – Americans' heart health is in a woeful state, says this year's report card from the American Heart Association. And it's largely because people just aren't taking care of themselves. In the past three or so decades, women have upped their calorie consumption by 22 percent and men by 10 percent, with carbohydrates and sugar-sweetened beverages both major sources of unneeded calories. The inevitable result is that more than two-thirds of U.S. adults and about one-third of children are over the ideal body weight, the extra layers of fat putting a major strain on Americans' hearts. The trend is particularly concerning in children. Today, about 20 percent of U.S. kids are obese, compared with just 4 percent 30 years ago. Neither adults nor children are exercising enough and about 21 percent of men and 18 percent of women still smoke. About one-fifth of high school ... Read more

Related support groups: High Blood Pressure, Hypertension, Heart Disease, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Prevention of Cardiovascular Disease, Lescol, Lescol XL, Mevacor, Baycol, Pitavastatin

Could Statins Help Those Hospitalized With Flu?

Posted 14 Dec 2011 by Drugs.com

WEDNESDAY, Dec. 14 – Statins, the drugs that can dramatically lower cholesterol levels, may one day also prove useful in combating serious cases of the flu. A preliminary study in the Journal of Infectious Diseases finds that patients hospitalized with influenza were less likely to die if they were taking a statin, compared with their peers who weren't taking one of the drugs. The effect held even after adjusting for heart disease. But it's far too soon to consider adding statins to the existing anti-flu armamentarium, the authors stated. "At this point, statins should not become the standard of care for people hospitalized with the flu," cautioned study co-author Dr. Ann Thomas, a public health physician with the Oregon Public Health Division in Portland. "We would like to see more studies, [and] I think it would be worthwhile to do these studies." Right now, preventive vaccinations ... Read more

Related support groups: Influenza, Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Baycol, Fluvastatin, Altoprev, Pitavastatin, Cerivastatin

Cholesterol-Lowering Drugs Safe for Long-Term Use, Study Finds

Posted 23 Nov 2011 by Drugs.com

TUESDAY, Nov. 22 – British researchers have good news for anyone taking the cholesterol-lowering medications known as statins: These drugs are effective and safe, even when used for long periods of time, they say. The 11-year study found that simvastatin (brand name Zocor) reduced the risk of cardiovascular disease by almost one-quarter. In addition, the researchers found no increase in illness or deaths from cancer or other non-vascular causes. "All those at increased vascular risk should start taking statins early and continue taking them long term," said the study's lead author, Dr. Richard Bulbulia, a consultant vascular surgeon and research fellow in the clinical trial service unit at the University of Oxford in England. "This will maximize the reductions in heart attacks, strokes and other vascular diseases, and is safe," said Bulbulia, who added that the study's findings should ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Pitavastatin, Baycol, Altoprev, Fluvastatin, Cerivastatin, Altocor

Statins Don't Raise Risk of Brain Bleeds After Stroke: Study

Posted 13 Sep 2011 by Drugs.com

TUESDAY, Sept. 13 – Statins, a widely prescribed class of drugs used to lower cholesterol, are not linked to an increased chance of brain bleeds in people who've had strokes, new research finds. Statins are commonly prescribed to people who've had an ischemic stroke, caused by blocked blood flow to the brain, to reduce the risk of another stroke. But two previous reviews raised concerns that statins might also raise the risk of bleeding in the brain. "We found no evidence that such patients are at higher risk for cerebral bleeding than individuals who do not receive statins," the authors wrote. "Physicians should continue to adhere to current treatment guidelines recommending statin therapy for most patients with a history of ischemic stroke." The study is published online in the Sept. 12 issue of the Archives of Neurology Researchers in Canada analyzed data on nearly 18,000 patients ... Read more

Related support groups: Lipitor, Simvastatin, Crestor, Pravastatin, Atorvastatin, Zocor, Lovastatin, Rosuvastatin, Livalo, Red Yeast Rice, Pravachol, Lescol, Lescol XL, Mevacor, Pitavastatin, Baycol, Altoprev, Fluvastatin, Cerivastatin, Altocor

Mainstay Meds Often Cut Off Accidentally After Hospital Stay

Posted 23 Aug 2011 by Drugs.com

TUESDAY, Aug. 23 – Many patients who are hospitalized fail to receive their regular medications for chronic conditions during their stay and often fail to restart them when they're discharged, researchers say. Patients treated in the intensive care unit (ICU) are even less likely to resume their regular medication schedule after discharge, probably because there are so many "transitions of care" to different units within the hospital and so many different care teams involved, the study found. "Sometimes we do a pretty good job of taking care of people in the hospital, but we don't do a great job of making the transition back to the community," said Dr. Chaim Bell, lead author of a study published in the Aug. 24/31 issue of the Journal of the American Medical Association. "That can lead to whole host of problems." Unintended discontinuation of vital medications can lead to another ... Read more

Related support groups: GERD, Asthma, Levothyroxine, Synthroid, Hypothyroidism, High Cholesterol, Lipitor, Simvastatin, Crestor, Underactive Thyroid, Pravastatin, Atorvastatin, Levoxyl, Zocor, Lovastatin, Levothroid, Rosuvastatin, Eltroxin, Livalo, Red Yeast Rice

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