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Patient's Pulmonary Valve May Substitute for Donor Aortic Valve
Posted 4 Aug 2010 by Drugs.com
TUESDAY, Aug. 3 – Heart patients who need a new aortic valve are more likely to survive and have a better quality of life if a valve from their own pulmonary artery is used, instead of an aortic valve from a dead donor, new research has found. The aortic valve connects the left ventricle of the heart with the aorta, which is the body's main artery. The pulmonary valve connects the heart to the pulmonary artery, which carries blood from the heart to the lungs. In this study, 108 patients had their malfunctioning aortic valve replaced with their own pulmonary valve (autograft). Their pulmonary valve was then replaced with a pulmonary valve from a dead donor. Another 108 patients had their aortic valve replaced with an aortic valve from a dead donor (homograft). After 10 years, four patients in the autograft group and 15 patients in the homograft group had died. This means that patients ... Read more
Related support groups: Prosthetic Heart Valves -- Tissue Valves
'Decellularized' Heart Valve Approved
Posted 7 Feb 2008 by Drugs.com
THURSDAY, Feb. 7 – The U.S. Food and Drug Administration has approved the first replacement heart valve from donated human tissue, in which the tissue's cells have been removed. Removing the tissue's cells and cellular debris is designed to lower the risk of an immune response from the body and subsequent tissue rejection, the FDA said in a statement. Cyrolife Inc's CyroValve SynerGraft pulmonary valve is designed for patients who need a replacement for a pulmonary valve because of disease, malformation or malfunction. The pulmonary valve directs blood flow from the heart's right ventricle to the lungs. Clinical studies compared results of 342 of the SynerGraft valves to 1,246 traditional valves. The FDA said it found that the new valves performed at least as well as the traditional ones. More information The FDA has more about this approval. Read more
Related support groups: Prosthetic Heart Valves -- Tissue Valves